BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND PTEN, MMAC1, 5728, MGC11227, PTEN1, MHAM, P60484, BZS, ENSG00000171862
1927 results:

  • 1. Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix.
    Bellone S; Jeong K; Halle MK; Krakstad C; McNamara B; Greenman M; Mutlu L; Demirkiran C; Hartwich TMP; Yang-Hartwich Y; Zipponi M; Buza N; Hui P; Raspagliesi F; Lopez S; Paolini B; Milione M; Perrone E; Scambia G; Altwerger G; Ravaggi A; Bignotti E; Huang GS; Andikyan V; Clark M; Ratner E; Azodi M; Schwartz PE; Quick CM; Angioli R; Terranova C; Zaidi S; Nandi S; Alexandrov LB; Siegel ER; Choi J; Schlessinger J; Santin AD
    Proc Natl Acad Sci U S A; 2024 Apr; 121(17):e2321898121. PubMed ID: 38625939
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Targeting Group 3 Medulloblastoma by the Anti-PRUNE-1 and Anti-LSD1/KDM1A Epigenetic Molecules.
    Bibbò F; Asadzadeh F; Boccia A; Sorice C; Bianco O; Saccà CD; Majello B; Donofrio V; Bifano D; De Martino L; Quaglietta L; Cristofano A; Covelli EM; Cinalli G; Ferrucci V; De Antonellis P; Zollo M
    Int J Mol Sci; 2024 Mar; 25(7):. PubMed ID: 38612726
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Combined deletion of MEN1, ATRX and pten triggers development of high-grade pancreatic neuroendocrine tumors in mice.
    Fuentes ME; Lu X; Flores NM; Hausmann S; Mazur PK
    Sci Rep; 2024 Apr; 14(1):8510. PubMed ID: 38609433
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of pten to induce an aggressive glioma phenotype.
    Nuechterlein N; Shelbourn A; Szulzewsky F; Arora S; Casad M; Pattwell S; Merino-Galan L; Sulman E; Arowa S; Alvinez N; Jung M; Brown D; Tang K; Jackson S; Stoica S; Chittaboina P; Banasavadi-Siddegowda YK; Wirsching HG; Stella N; Shapiro L; Paddison P; Patel AP; Gilbert MR; Abdullaev Z; Aldape K; Pratt D; Holland EC; Cimino PJ
    Genes Dev; 2024 Apr; 38(5-6):273-288. PubMed ID: 38589034
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Quantifying intra-tumoral genetic heterogeneity of glioblastoma toward precision medicine using MRI and a data-inclusive machine learning algorithm.
    Wang L; Wang H; D'Angelo F; Curtin L; Sereduk CP; Leon G; Singleton KW; Urcuyo J; Hawkins-Daarud A; Jackson PR; Krishna C; Zimmerman RS; Patra DP; Bendok BR; Smith KA; Nakaji P; Donev K; Baxter LC; Mrugała MM; Ceccarelli M; Iavarone A; Swanson KR; Tran NL; Hu LS; Li J
    PLoS One; 2024; 19(4):e0299267. PubMed ID: 38568950
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Role of Surgery in Metastatic Melanoma and Review of Melanoma Molecular Characteristics.
    Sukniam K; Manaise HK; Popp K; Popp R; Gabriel E
    Cells; 2024 Mar; 13(6):. PubMed ID: 38534309
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Reactivating pten to impair glioma stem cells by inhibiting cytosolic iron-sulfur assembly.
    Yin J; Ge X; Ding F; He L; Song K; Shi Z; Ge Z; Zhang J; Ji J; Wang X; Zhao N; Shu C; Lin F; Wang Q; Zhou Q; Cao Y; Liu W; Ye D; Rich JN; Wang X; You Y; Qian X
    Sci Transl Med; 2024 Mar; 16(739):eadg5553. PubMed ID: 38507470
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Glioblastoma Therapy: Past, Present and Future.
    Obrador E; Moreno-Murciano P; Oriol-Caballo M; López-Blanch R; Pineda B; Gutiérrez-Arroyo JL; Loras A; Gonzalez-Bonet LG; Martinez-Cadenas C; Estrela JM; Marqués-Torrejón MÁ
    Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473776
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The Role of the pten tumor Suppressor Gene and Its Anti-Angiogenic Activity in Melanoma and Other Cancers.
    Maphutha J; Twilley D; Lall N
    Molecules; 2024 Feb; 29(3):. PubMed ID: 38338464
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Molecular signature of stem-like glioma cells (SLGCs) from human glioblastoma and gliosarcoma.
    Zechel C; Loy M; Wegner C; Dahlke E; Soetje B; Baehr L; Leppert J; Ostermaier JJ; Lueg T; Nielsen J; Elßner J; Willeke V; Marzahl S; Tronnier V; Madany Mamlouk A
    PLoS One; 2024; 19(2):e0291368. PubMed ID: 38306361
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Pholiotic acid promotes apoptosis in human metastatic melanoma cells.
    Avola R; Graziano ACE; Madrid A; Clericuzio M; Cardile V; Russo A
    Chem Biol Interact; 2024 Feb; 390():110894. PubMed ID: 38301881
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Extracellular Vesicles Derived from Glioma Stem cells Affect Glycometabolic Reprogramming of Glioma cells Through the miR-10b-5p/pten/PI3K/Akt Pathway.
    Li S; Mao L; Song L; Xia X; Wang Z; Cheng Y; Lai J; Tang X; Chen X
    Stem Cell Rev Rep; 2024 Apr; 20(3):779-796. PubMed ID: 38294721
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. tumor characteristics of dissociated response to immune checkpoint inhibition in advanced melanoma.
    Versluis JM; Hoefsmit EP; Shehwana H; Dimitriadis P; Sanders J; Broeks A; Blank CU
    Cancer Immunol Immunother; 2024 Jan; 73(2):28. PubMed ID: 38280045
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. GlioPredictor: a deep learning model for identification of high-risk adult IDH-mutant glioma towards adjuvant treatment planning.
    Zheng S; Rammohan N; Sita T; Teo PT; Wu Y; Lesniak M; Sachdev S; Thomas TO
    Sci Rep; 2024 Jan; 14(1):2126. PubMed ID: 38267516
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The genomic alterations in glioblastoma influence the levels of CSF metabolites.
    Wang DH; Fujita Y; Dono A; Rodriguez Armendariz AG; Shah M; Putluri N; Pichardo-Rojas PS; Patel CB; Zhu JJ; Huse JT; Parker Kerrigan BC; Lang FF; Esquenazi Y; Ballester LY
    Acta Neuropathol Commun; 2024 Jan; 12(1):13. PubMed ID: 38243318
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. cell-free DNA fragmentomics and second malignant neoplasm risk in patients with pten hamartoma tumor syndrome.
    Liu D; Yehia L; Dhawan A; Ni Y; Eng C
    Cell Rep Med; 2024 Feb; 5(2):101384. PubMed ID: 38242121
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Cooperative function of oncogenic MAPK signaling and the loss of pten for melanoma migration through the formation of lamellipodia.
    Yasuta Y; Kaminaka R; Nagai S; Mouri S; Ishida K; Tanaka A; Zhou Y; Sakurai H; Yokoyama S
    Sci Rep; 2024 Jan; 14(1):1525. PubMed ID: 38233537
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Reliable detection of genetic alterations in cyst fluid DNA for the diagnosis of brain tumors.
    On J; Natsumeda M; Takahashi H; Koyama A; Shibuma S; Shibata N; Watanabe J; Saito S; Kanemaru Y; Tsukamoto Y; Okada M; Ogura R; Eda T; Tada M; Shimizu H; Adachi JI; Mishima K; Nishikawa R; Kakita A; Oishi M
    J Neurooncol; 2024 Jan; 166(2):273-282. PubMed ID: 38227143
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Thiol starvation triggers melanoma state switching in an ATF4 and NRF2-dependent manner.
    Meinert M; Jessen C; Hufnagel A; Kreß JKC; Burnworth M; Däubler T; Gallasch T; Xavier da Silva TN; Dos Santos AF; Ade CP; Schmitz W; Kneitz S; Friedmann Angeli JP; Meierjohann S
    Redox Biol; 2024 Apr; 70():103011. PubMed ID: 38219574
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Investigating the effects of pten mutations on cGAS-STING pathway in glioblastoma tumours.
    Dogan E; Yildirim Z; Akalin T; Ozgiray E; Akinturk N; Aktan C; Solmaz AE; Biceroglu H; Caliskan KE; Ertan Y; Yurtseven T; Kosova B; Bozok V
    J Neurooncol; 2024 Jan; 166(2):283-292. PubMed ID: 38214828
    [TBL] [Abstract] [Full Text] [Related]  


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