Terms: = Germ cell tumor AND PTPN11, CFC, Q06124, 5781, ENSG00000179295, SHP2, MGC14433, SHP-2, BPTP3, PTP-1D, SH-PTP3, NS1, SH-PTP2, PTP2C
183 results:
1. The Oncolytic Activity of Zika Viral Therapy in Human Neuroblastoma In Vivo Models Confers a Major Survival Advantage in a CD24-dependent Manner.
Mazar J; Brooks JK; Peloquin M; Rosario R; Sutton E; Longo M; Drehner D; Westmoreland TJ
Cancer Res Commun; 2024 Jan; 4(1):65-80. PubMed ID: 38214542
[TBL] [Abstract] [Full Text] [Related]
2. shp2 Inhibition with TNO155 Increases Efficacy and Overcomes Resistance of ALK Inhibitors in Neuroblastoma.
Valencia-Sama I; Kee L; Christopher G; Ohh M; Layeghifard M; Shlien A; Hayes MN; Irwin MS
Cancer Res Commun; 2023 Dec; 3(12):2608-2622. PubMed ID: 38032104
[TBL] [Abstract] [Full Text] [Related]
3. LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines.
Wei X; Pan S; Wang Z; Chen J; Lu L; Cao Q; Song S; Zhang H; Liu X; Qu X; Lin X; Xu H
Cell Death Dis; 2023 Oct; 14(10):684. PubMed ID: 37845206
[TBL] [Abstract] [Full Text] [Related]
4. Exogenous recombinant N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) inhibits progression of B16F10 cutaneous melanomas and modulates cell signaling.
Bhattacharyya S; O-Sullivan I; Tu J; Chen Z; Tobacman JK
Biochim Biophys Acta Mol Basis Dis; 2024 Jan; 1870(1):166913. PubMed ID: 37813168
[TBL] [Abstract] [Full Text] [Related]
5. Dysregulated ceramides metabolism via ptpn11 exposes a metabolic vulnerability to breast cancer metastasis.
Qiao S; Wang T; Wang H
Med Oncol; 2023 Sep; 40(11):310. PubMed ID: 37773553
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6. ptpn11 variant may be a prognostic indicator of IDH-wildtype glioblastoma in a comprehensive genomic profiling cohort.
Otani R; Ikegami M; Yamada R; Yajima H; Kawamura S; Shimizu S; Tanaka S; Takayanagi S; Takami H; Yamaguchi T
J Neurooncol; 2023 Aug; 164(1):221-229. PubMed ID: 37552362
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7. Resveratrol Enhances Temozolomide Efficacy in Glioblastoma cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
Wu M; Song D; Li H; Ahmad N; Xu H; Yang X; Wang Q; Cheng X; Deng S; Shu X
Int J Mol Sci; 2023 May; 24(11):. PubMed ID: 37298405
[TBL] [Abstract] [Full Text] [Related]
8. RNA-Sequencing Combined With Genome-Wide Allele-Specific Expression Patterning Identifies ZNF44 Variants as a Potential New Driver Gene for Pediatric Neuroblastoma.
Sun L; Li X; Tu L; Stucky A; Huang C; Chen X; Cai J; Li SC
Cancer Control; 2023; 30():10732748231175017. PubMed ID: 37161925
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9. Mapping the landscape of genetic dependencies in chordoma.
Sharifnia T; Wawer MJ; Goodale A; Lee Y; Kazachkova M; Dempster JM; Muller S; Levy J; Freed DM; Sommer J; Kalfon J; Vazquez F; Hahn WC; Root DE; Clemons PA; Schreiber SL
Nat Commun; 2023 Apr; 14(1):1933. PubMed ID: 37024492
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10. Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in ptpn11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes.
Hoffmann L; Coras R; Kobow K; López-Rivera JA; Lal D; Leu C; Najm I; Nürnberg P; Herms J; Harter PN; Bien CG; Kalbhenn T; Müller M; Pieper T; Hartlieb T; Kudernatsch M; Hamer H; Brandner S; Rössler K; Blümcke I; Jabari S
Acta Neuropathol; 2023 Jun; 145(6):815-827. PubMed ID: 36973520
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11. tumor cell-Autonomous shp2 Contributes to Immune Suppression in Metastatic Breast Cancer.
Chen H; Cresswell GM; Libring S; Ayers MG; Miao J; Zhang ZY; Solorio L; Ratliff TL; Wendt MK
Cancer Res Commun; 2022 Oct; 2(10):1104-1118. PubMed ID: 36969745
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12. Whole-exome sequencing reveals genetic variants in low-risk and high-risk neuroblastoma.
Altun Z; Yuan H; Baran B; Aktaş S; Sönmez EE; Küçük C; Olgun N
Gene; 2023 Apr; 860():147233. PubMed ID: 36736507
[TBL] [Abstract] [Full Text] [Related]
13. ptpn11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma.
Polubothu S; Bender N; Muthiah S; Zecchin D; Demetriou C; Martin SB; Malhotra S; Travnickova J; Zeng Z; Böhm M; Barbarot S; Cottrell C; Davies O; Baselga E; Burrows NP; Carmignac V; Diaz JS; Fink C; Haenssle HA; Happle R; Harland M; Majerowski J; Vabres P; Vincent M; Newton-Bishop JA; Bishop DT; Siegel D; Patton EE; Topf M; Rajan N; Drolet B; Kinsler VA
J Invest Dermatol; 2023 Jun; 143(6):1042-1051.e3. PubMed ID: 36566878
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14. Pan-tumor landscape of fibroblast growth factor receptor 1-4 genomic alterations.
Murugesan K; Necchi A; Burn TC; Gjoerup O; Greenstein R; Krook M; López JA; Montesion M; Nimeiri H; Parikh AR; Roychowdhury S; Schwemmers S; Silverman IM; Vogel A
ESMO Open; 2022 Dec; 7(6):100641. PubMed ID: 36462464
[TBL] [Abstract] [Full Text] [Related]
15. Fibrous dysplasia in cardio-facio-cutaneous syndrome: A case report and review of literature.
Dong X; Png NCY; Fortier MV; Lim JY; Wong KPL; Choo JTL; Tan EC; Jamuar SS
Am J Med Genet A; 2022 Sep; 188(9):2732-2737. PubMed ID: 35801299
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16. Lateralized overgrowth with vascular malformation caused by a somatic ptpn11 pathogenic variant: Another piece added to the puzzle of mosaic RASopathies.
Mussa A; Turchiano A; Cardaropoli S; Coppo P; Pantaleo A; Bagnulo R; Ranieri C; Iacoviello M; Garganese A; Stella A; Vallero SG; Bertin D; Santoro F; Carli D; Ferrero GB; Resta N
Genes Chromosomes Cancer; 2022 Nov; 61(11):689-695. PubMed ID: 35778969
[TBL] [Abstract] [Full Text] [Related]
17. H3K27M-Altered Diffuse Midline Gliomas Among Adult Patients: A Systematic Review of Clinical Features and Survival Analysis.
Bin-Alamer O; Jimenez AE; Azad TD; Bettegowda C; Mukherjee D
World Neurosurg; 2022 Sep; 165():e251-e264. PubMed ID: 35697228
[TBL] [Abstract] [Full Text] [Related]
18. Design, synthesis and biological evaluation of novel triazoloquinazolinone and imidazoquinazolinone derivatives as allosteric inhibitors of shp2 phosphatase.
Ye W; Liu Y; Ren Q; Liao T; Chen Y; Chen D; Wang S; Yao L; Jia Y; Zhao C; Zhou Z
J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1495-1513. PubMed ID: 35635145
[TBL] [Abstract] [Full Text] [Related]
19. Thoracic low grade glial neoplasm with concurrent H3 K27M and ptpn11 mutations.
Argenziano MG; Furnari JL; Miller ML; Sun Y; Banu MA; Neira JA; Snuderl M; Bruce JN; Welch M; McCormick P; Canoll P
Acta Neuropathol Commun; 2022 Apr; 10(1):64. PubMed ID: 35484611
[TBL] [Abstract] [Full Text] [Related]
20. ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma.
Arrieta VA; Chen AX; Kane JR; Kang SJ; Kassab C; Dmello C; Zhao J; Burdett KB; Upadhyayula PS; Lee-Chang C; Shilati J; Jaishankar D; Chen L; Gould A; Zhang D; Yuan J; Zhao W; Ling X; Burks JK; Laffleur B; Amidei C; Bruce JN; Lukas RV; Yamaguchi JT; Cieremans D; Rothschild G; Basu U; McCord M; Brat DJ; Zhang H; Cooper LAD; Zhang B; Sims P; Cloughesy TF; Prins R; Canoll P; Stupp R; Heimberger AB; Horbinski C; Iwamoto FM; Rabadan R; Sonabend AM
Nat Cancer; 2021 Dec; 2(12):1372-1386. PubMed ID: 35121903
[TBL] [Abstract] [Full Text] [Related]
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