Terms: = Germ cell tumor AND PTPN11, CFC, Q06124, 5781, ENSG00000179295, SHP2, MGC14433, SHP-2, BPTP3, PTP-1D, SH-PTP3, NS1, SH-PTP2, PTP2C AND Treatment
51 results:
1. The Oncolytic Activity of Zika Viral Therapy in Human Neuroblastoma In Vivo Models Confers a Major Survival Advantage in a CD24-dependent Manner.
Mazar J; Brooks JK; Peloquin M; Rosario R; Sutton E; Longo M; Drehner D; Westmoreland TJ
Cancer Res Commun; 2024 Jan; 4(1):65-80. PubMed ID: 38214542
[TBL] [Abstract] [Full Text] [Related]
2. shp2 Inhibition with TNO155 Increases Efficacy and Overcomes Resistance of ALK Inhibitors in Neuroblastoma.
Valencia-Sama I; Kee L; Christopher G; Ohh M; Layeghifard M; Shlien A; Hayes MN; Irwin MS
Cancer Res Commun; 2023 Dec; 3(12):2608-2622. PubMed ID: 38032104
[TBL] [Abstract] [Full Text] [Related]
3. Exogenous recombinant N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) inhibits progression of B16F10 cutaneous melanomas and modulates cell signaling.
Bhattacharyya S; O-Sullivan I; Tu J; Chen Z; Tobacman JK
Biochim Biophys Acta Mol Basis Dis; 2024 Jan; 1870(1):166913. PubMed ID: 37813168
[TBL] [Abstract] [Full Text] [Related]
4. Resveratrol Enhances Temozolomide Efficacy in Glioblastoma cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
Wu M; Song D; Li H; Ahmad N; Xu H; Yang X; Wang Q; Cheng X; Deng S; Shu X
Int J Mol Sci; 2023 May; 24(11):. PubMed ID: 37298405
[TBL] [Abstract] [Full Text] [Related]
5. tumor cell-Autonomous shp2 Contributes to Immune Suppression in Metastatic Breast Cancer.
Chen H; Cresswell GM; Libring S; Ayers MG; Miao J; Zhang ZY; Solorio L; Ratliff TL; Wendt MK
Cancer Res Commun; 2022 Oct; 2(10):1104-1118. PubMed ID: 36969745
[TBL] [Abstract] [Full Text] [Related]
6. Lateralized overgrowth with vascular malformation caused by a somatic ptpn11 pathogenic variant: Another piece added to the puzzle of mosaic RASopathies.
Mussa A; Turchiano A; Cardaropoli S; Coppo P; Pantaleo A; Bagnulo R; Ranieri C; Iacoviello M; Garganese A; Stella A; Vallero SG; Bertin D; Santoro F; Carli D; Ferrero GB; Resta N
Genes Chromosomes Cancer; 2022 Nov; 61(11):689-695. PubMed ID: 35778969
[TBL] [Abstract] [Full Text] [Related]
7. Genomic data from NSCLC tumors reveals correlation between shp-2 activity and PD-L1 expression and suggests synergy in combining shp-2 and PD-1/PD-L1 inhibitors.
Toral KJ; Wuenschel MA; Black EP
PLoS One; 2021; 16(8):e0256416. PubMed ID: 34437586
[TBL] [Abstract] [Full Text] [Related]
8. Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling.
Dardis C; Donner D; Sanai N; Xiu J; Mittal S; Michelhaugh SK; Pandey M; Kesari S; Heimberger AB; Gatalica Z; Korn MW; Sumrall AL; Phuphanich S
BMC Neurol; 2021 Jun; 21(1):231. PubMed ID: 34162346
[TBL] [Abstract] [Full Text] [Related]
9. Spinal cord glioblastoma multiforme in a patient with Noonan syndrome: A clinical report.
Khan A; Soliman MAR; Ghannam MM; Jowdy PK; Hess R; Recker MJ; Reynolds RM
Clin Neurol Neurosurg; 2021 Aug; 207():106725. PubMed ID: 34153779
[TBL] [Abstract] [Full Text] [Related]
10. Proteogenomic and metabolomic characterization of human glioblastoma.
Wang LB; Karpova A; Gritsenko MA; Kyle JE; Cao S; Li Y; Rykunov D; Colaprico A; Rothstein JH; Hong R; Stathias V; Cornwell M; Petralia F; Wu Y; Reva B; Krug K; Pugliese P; Kawaler E; Olsen LK; Liang WW; Song X; Dou Y; Wendl MC; Caravan W; Liu W; Cui Zhou D; Ji J; Tsai CF; Petyuk VA; Moon J; Ma W; Chu RK; Weitz KK; Moore RJ; Monroe ME; Zhao R; Yang X; Yoo S; Krek A; Demopoulos A; Zhu H; Wyczalkowski MA; McMichael JF; Henderson BL; Lindgren CM; Boekweg H; Lu S; Baral J; Yao L; Stratton KG; Bramer LM; Zink E; Couvillion SP; Bloodsworth KJ; Satpathy S; Sieh W; Boca SM; Schürer S; Chen F; Wiznerowicz M; Ketchum KA; Boja ES; Kinsinger CR; Robles AI; Hiltke T; Thiagarajan M; Nesvizhskii AI; Zhang B; Mani DR; Ceccarelli M; Chen XS; Cottingham SL; Li QK; Kim AH; Fenyö D; Ruggles KV; Rodriguez H; Mesri M; Payne SH; Resnick AC; Wang P; Smith RD; Iavarone A; Chheda MG; Barnholtz-Sloan JS; Rodland KD; Liu T; Ding L;
Cancer Cell; 2021 Apr; 39(4):509-528.e20. PubMed ID: 33577785
[TBL] [Abstract] [Full Text] [Related]
11. Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.
Hou Y; Sun B; Liu W; Yu B; Shi Q; Luo F; Bai Y; Feng H
Theranostics; 2021; 11(2):555-566. PubMed ID: 33391492
[TBL] [Abstract] [Full Text] [Related]
12.
Valencia-Sama I; Ladumor Y; Kee L; Adderley T; Christopher G; Robinson CM; Kano Y; Ohh M; Irwin MS
Cancer Res; 2020 Aug; 80(16):3413-3423. PubMed ID: 32586982
[TBL] [Abstract] [Full Text] [Related]
13. Comprehensive Genomic Analysis of Noonan Syndrome and Acute Myeloid Leukemia in Adults: A Review and Future Directions.
Alhumaid MS; Dasouki MJ; Ahmed SO; AbalKhail H; Hagos S; Wakil S; Hashmi SK
Acta Haematol; 2020; 143(6):583-593. PubMed ID: 32541138
[TBL] [Abstract] [Full Text] [Related]
14. Newcastle Disease Virus (NDV) Oncolytic Activity in Human Glioma tumors Is Dependent on CDKN2A-Type I IFN Gene Cluster Codeletion.
García-Romero N; Palacín-Aliana I; Esteban-Rubio S; Madurga R; Rius-Rocabert S; Carrión-Navarro J; Presa J; Cuadrado-Castano S; Sánchez-Gómez P; García-Sastre A; Nistal-Villan E; Ayuso-Sacido A
Cells; 2020 Jun; 9(6):. PubMed ID: 32516884
[TBL] [Abstract] [Full Text] [Related]
15. The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade.
Okoye IS; Xu L; Walker J; Elahi S
Cancer Immunol Immunother; 2020 Aug; 69(8):1423-1436. PubMed ID: 32246174
[TBL] [Abstract] [Full Text] [Related]
16. Targeting PDGFRα-activated glioblastoma through specific inhibition of shp-2-mediated signaling.
Sang Y; Hou Y; Cheng R; Zheng L; Alvarez AA; Hu B; Cheng SY; Zhang W; Li Y; Feng H
Neuro Oncol; 2019 Nov; 21(11):1423-1435. PubMed ID: 31232447
[TBL] [Abstract] [Full Text] [Related]
17. Zika virus NS5 protein inhibits cell growth and invasion of glioma.
Li H; Hu Y; Huang J; Feng Y; Zhang Z; Zhong K; Chen Y; Wang Z; Huang C; Yang H; Tong A
Biochem Biophys Res Commun; 2019 Aug; 516(2):515-520. PubMed ID: 31230744
[TBL] [Abstract] [Full Text] [Related]
18. Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma.
Zhao J; Chen AX; Gartrell RD; Silverman AM; Aparicio L; Chu T; Bordbar D; Shan D; Samanamud J; Mahajan A; Filip I; Orenbuch R; Goetz M; Yamaguchi JT; Cloney M; Horbinski C; Lukas RV; Raizer J; Rae AI; Yuan J; Canoll P; Bruce JN; Saenger YM; Sims P; Iwamoto FM; Sonabend AM; Rabadan R
Nat Med; 2019 Mar; 25(3):462-469. PubMed ID: 30742119
[TBL] [Abstract] [Full Text] [Related]
19. Is Resection of Primary Midgut Neuroendocrine tumors in Patients with Unresectable Metastatic Liver Disease Justified? A Systematic Review and Meta-Analysis.
Tsilimigras DI; Ntanasis-Stathopoulos I; Kostakis ID; Moris D; Schizas D; Cloyd JM; Pawlik TM
J Gastrointest Surg; 2019 May; 23(5):1044-1054. PubMed ID: 30671800
[TBL] [Abstract] [Full Text] [Related]
20. Trametinib for progressive pediatric low-grade gliomas.
Kondyli M; Larouche V; Saint-Martin C; Ellezam B; Pouliot L; Sinnett D; Legault G; Crevier L; Weil A; Farmer JP; Jabado N; Perreault S
J Neurooncol; 2018 Nov; 140(2):435-444. PubMed ID: 30097824
[TBL] [Abstract] [Full Text] [Related]
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