BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25
327 results:

  • 1. Tiam1 regulates proliferation, invasion, and differentiation in neuroblastoma through the Tiam1/rac1 signaling pathway.
    Li X; Liu B; Wang X; Zhuang Y; Gao T; Sun N
    Neoplasma; 2024 Feb; 71(1):37-47. PubMed ID: 38506031
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Unique vulnerability of rac1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints.
    Cannon AC; Budagyan K; Uribe-Alvarez C; Kurimchak AM; Araiza-Olivera D; Cai KQ; Peri S; Zhou Y; Duncan JS; Chernoff J
    Oncogene; 2024 Mar; 43(10):729-743. PubMed ID: 38243078
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Taxifolin inhibits melanoma proliferation/migration impeding USP18/rac1/JNK/β-catenin oncogenic signaling.
    Xu L; Zhang L; Zhang S; Yang J; Zhu A; Sun J; Kalvakolanu DV; Cong X; Zhang J; Tang J; Guo B
    Phytomedicine; 2024 Jan; 123():155199. PubMed ID: 37995531
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress.
    Zhou W; Zhao Z; Lin A; Yang JZ; Xu J; Wilder-Romans K; Yang A; Li J; Solanki S; Speth JM; Walker N; Scott AJ; Wang L; Wen B; Andren A; Zhang L; Kothari AU; Yao Y; Peterson ER; Korimerla N; Werner CK; Ullrich A; Liang J; Jacobson J; Palavalasa S; O'Brien AM; Elaimy AL; Ferris SP; Zhao SG; Sarkaria JN; Győrffy B; Zhang S; Al-Holou WN; Umemura Y; Morgan MA; Lawrence TS; Lyssiotis CA; Peters-Golden M; Shah YM; Wahl DR
    Cancer Discov; 2024 Jan; 14(1):158-175. PubMed ID: 37902550
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. PAK1 and Therapy Resistance in Melanoma.
    Kichina JV; Maslov A; Kandel ES
    Cells; 2023 Sep; 12(19):. PubMed ID: 37830586
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a rac1-driven ROS production.
    Magalhaes YT; Forti FL
    Int J Biochem Cell Biol; 2023 Nov; 164():106474. PubMed ID: 37778694
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Upregulation of miR-22 alleviates oxygen-glucose deprivation/reperfusion-induced injury by targeting Tiam1 in SH-SY5Y cells.
    Yin J; Wan Y; Wang J; Xue M
    Acta Biochim Pol; 2023 Sep; 70(3):495-501. PubMed ID: 37672720
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Primary mucosal melanomas of the urogenital tract: a clinical, pathological, and genetic nationwide survey of Danish patients 1990-2019.
    Znaider VK; Mikkelsen LH; Jensen CFS; Sønksen J; Heegaard S
    Scand J Urol; 2023 Aug; 58():52-59. PubMed ID: 37635444
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Integrative multiomics analysis identifies a metastasis-related gene signature and the potential oncogenic role of EZR in breast cancer.
    Xiao G; Cheng F; Yuan J; Lu W; Wang P; Fan H
    Oncol Res; 2022; 30(1):35-51. PubMed ID: 37304008
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. A comprehensive signature based on endoplasmic reticulum stress-related genes in predicting prognosis and immunotherapy response in melanoma.
    Liu L; Yao D; Chen Z; Duan S
    Sci Rep; 2023 May; 13(1):8232. PubMed ID: 37217516
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Sema3C signaling is an alternative activator of the canonical WNT pathway in glioblastoma.
    Hao J; Han X; Huang H; Yu X; Fang J; Zhao J; Prayson RA; Bao S; Yu JS
    Nat Commun; 2023 Apr; 14(1):2262. PubMed ID: 37080989
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Whole-Exome Sequencing and cfDNA Analysis Uncover Genetic Determinants of Melanoma Therapy Response in a Real-World Setting.
    Vanni I; Pastorino L; Tanda ET; Andreotti V; Dalmasso B; Solari N; Mascherini M; Cabiddu F; Guadagno A; Coco S; Allavena E; Bruno W; Pietra G; Croce M; Gangemi R; Piana M; Zoppoli G; Ferrando L; Spagnolo F; Queirolo P; Ghiorzo P
    Int J Mol Sci; 2023 Feb; 24(5):. PubMed ID: 36901733
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Characterisation and outcome of rac1 mutated melanoma.
    Lodde GC; Jansen P; Herbst R; Terheyden P; Utikal J; Pföhler C; Ulrich J; Kreuter A; Mohr P; Gutzmer R; Meier F; Dippel E; Weichenthal M; Sucker A; Placke JM; Zaremba A; Albrecht LJ; Kowall B; Galetzka W; Becker JC; Tasdogan A; Zimmer L; Livingstone E; Hadaschik E; Schadendorf D; Ugurel S; Griewank K
    Eur J Cancer; 2023 Apr; 183():1-10. PubMed ID: 36773463
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on rac1 level and migration of medulloblastoma in vitro.
    Schoen LF; Craveiro RB; Pietsch T; Moritz T; Troeger A; Jordans S; Dilloo D
    J Cell Mol Med; 2022 Dec; 26(23):5832-5845. PubMed ID: 36377725
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Anti‑tumor effects of anti‑epileptic drugs in malignant glioma cells.
    Yagi C; Tatsuoka J; Sano E; Hanashima Y; Ozawa Y; Yoshimura S; Yamamuro S; Sumi K; Hara H; Katayama Y; Yoshino A
    Oncol Rep; 2022 Dec; 48(6):. PubMed ID: 36281939
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. A distinct pattern of growth and rac1 signaling in melanoma brain metastasis cells.
    Stejerean-Todoran I; Gimotty PA; Watters A; Brafford P; Krepler C; Godok T; Li H; Bonilla Del Rio Z; Zieseniss A; Katschinski DM; Sertel SM; Rizzoli SO; Garman B; Nathanson KL; Xu X; Chen Q; Oswald JH; Lotem M; Mills GB; Davies MA; Schön MP; Bogeski I; Herlyn M; Vultur A
    Neuro Oncol; 2023 Apr; 25(4):674-686. PubMed ID: 36054930
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Monensin synergizes with chemotherapy in uveal melanoma through suppressing RhoA.
    Zeng C; Long M; Lu Y
    Immunopharmacol Immunotoxicol; 2023 Feb; 45(1):35-42. PubMed ID: 36043455
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Machine learning approach informs biology of cancer drug response.
    Zhu EY; Dupuy AJ
    BMC Bioinformatics; 2022 May; 23(1):184. PubMed ID: 35581546
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. FMRP ligand circZNF609 destabilizes rac1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma.
    Shang Q; Du H; Wu X; Guo Q; Zhang F; Gong Z; Jiao T; Guo J; Kong Y
    J Exp Clin Cancer Res; 2022 May; 41(1):170. PubMed ID: 35534866
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Elevated non-coding promoter mutations are associated with malignant transformation of melanocytic naevi to melanoma.
    Colebatch AJ; Paver EC; Vergara IA; Thompson JF; Long GV; Wilmott JS; Scolyer RA
    Pathology; 2022 Aug; 54(5):533-540. PubMed ID: 35248370
    [TBL] [Abstract] [Full Text] [Related]  


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