Terms: = Germ cell tumor AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
83 results:
1. Taxifolin inhibits melanoma proliferation/migration impeding USP18/rac1/JNK/β-catenin oncogenic signaling.
Xu L; Zhang L; Zhang S; Yang J; Zhu A; Sun J; Kalvakolanu DV; Cong X; Zhang J; Tang J; Guo B
Phytomedicine; 2024 Jan; 123():155199. PubMed ID: 37995531
[TBL] [Abstract] [Full Text] [Related]
2. GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress.
Zhou W; Zhao Z; Lin A; Yang JZ; Xu J; Wilder-Romans K; Yang A; Li J; Solanki S; Speth JM; Walker N; Scott AJ; Wang L; Wen B; Andren A; Zhang L; Kothari AU; Yao Y; Peterson ER; Korimerla N; Werner CK; Ullrich A; Liang J; Jacobson J; Palavalasa S; O'Brien AM; Elaimy AL; Ferris SP; Zhao SG; Sarkaria JN; Győrffy B; Zhang S; Al-Holou WN; Umemura Y; Morgan MA; Lawrence TS; Lyssiotis CA; Peters-Golden M; Shah YM; Wahl DR
Cancer Discov; 2024 Jan; 14(1):158-175. PubMed ID: 37902550
[TBL] [Abstract] [Full Text] [Related]
3. ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a rac1-driven ROS production.
Magalhaes YT; Forti FL
Int J Biochem Cell Biol; 2023 Nov; 164():106474. PubMed ID: 37778694
[TBL] [Abstract] [Full Text] [Related]
4. Primary mucosal melanomas of the urogenital tract: a clinical, pathological, and genetic nationwide survey of Danish patients 1990-2019.
Znaider VK; Mikkelsen LH; Jensen CFS; Sønksen J; Heegaard S
Scand J Urol; 2023 Aug; 58():52-59. PubMed ID: 37635444
[TBL] [Abstract] [Full Text] [Related]
5. A comprehensive signature based on endoplasmic reticulum stress-related genes in predicting prognosis and immunotherapy response in melanoma.
Liu L; Yao D; Chen Z; Duan S
Sci Rep; 2023 May; 13(1):8232. PubMed ID: 37217516
[TBL] [Abstract] [Full Text] [Related]
6. Whole-Exome Sequencing and cfDNA Analysis Uncover Genetic Determinants of Melanoma Therapy Response in a Real-World Setting.
Vanni I; Pastorino L; Tanda ET; Andreotti V; Dalmasso B; Solari N; Mascherini M; Cabiddu F; Guadagno A; Coco S; Allavena E; Bruno W; Pietra G; Croce M; Gangemi R; Piana M; Zoppoli G; Ferrando L; Spagnolo F; Queirolo P; Ghiorzo P
Int J Mol Sci; 2023 Feb; 24(5):. PubMed ID: 36901733
[TBL] [Abstract] [Full Text] [Related]
7. Characterisation and outcome of rac1 mutated melanoma.
Lodde GC; Jansen P; Herbst R; Terheyden P; Utikal J; Pföhler C; Ulrich J; Kreuter A; Mohr P; Gutzmer R; Meier F; Dippel E; Weichenthal M; Sucker A; Placke JM; Zaremba A; Albrecht LJ; Kowall B; Galetzka W; Becker JC; Tasdogan A; Zimmer L; Livingstone E; Hadaschik E; Schadendorf D; Ugurel S; Griewank K
Eur J Cancer; 2023 Apr; 183():1-10. PubMed ID: 36773463
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8. The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on rac1 level and migration of medulloblastoma in vitro.
Schoen LF; Craveiro RB; Pietsch T; Moritz T; Troeger A; Jordans S; Dilloo D
J Cell Mol Med; 2022 Dec; 26(23):5832-5845. PubMed ID: 36377725
[TBL] [Abstract] [Full Text] [Related]
9. Anti‑tumor effects of anti‑epileptic drugs in malignant glioma cells.
Yagi C; Tatsuoka J; Sano E; Hanashima Y; Ozawa Y; Yoshimura S; Yamamuro S; Sumi K; Hara H; Katayama Y; Yoshino A
Oncol Rep; 2022 Dec; 48(6):. PubMed ID: 36281939
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10. A distinct pattern of growth and rac1 signaling in melanoma brain metastasis cells.
Stejerean-Todoran I; Gimotty PA; Watters A; Brafford P; Krepler C; Godok T; Li H; Bonilla Del Rio Z; Zieseniss A; Katschinski DM; Sertel SM; Rizzoli SO; Garman B; Nathanson KL; Xu X; Chen Q; Oswald JH; Lotem M; Mills GB; Davies MA; Schön MP; Bogeski I; Herlyn M; Vultur A
Neuro Oncol; 2023 Apr; 25(4):674-686. PubMed ID: 36054930
[TBL] [Abstract] [Full Text] [Related]
11. Monensin synergizes with chemotherapy in uveal melanoma through suppressing RhoA.
Zeng C; Long M; Lu Y
Immunopharmacol Immunotoxicol; 2023 Feb; 45(1):35-42. PubMed ID: 36043455
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12. FMRP ligand circZNF609 destabilizes rac1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma.
Shang Q; Du H; Wu X; Guo Q; Zhang F; Gong Z; Jiao T; Guo J; Kong Y
J Exp Clin Cancer Res; 2022 May; 41(1):170. PubMed ID: 35534866
[TBL] [Abstract] [Full Text] [Related]
13. Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer.
Celus W; Oliveira AI; Rivis S; Van Acker HH; Landeloos E; Serneels J; Cafarello ST; Van Herck Y; Mastrantonio R; Köhler A; Garg AD; Flamand V; Tamagnone L; Marine JC; Di Matteo M; Costa BM; Bechter O; Mazzone M
Cancer Immunol Res; 2022 Jan; 10(1):126-141. PubMed ID: 34815265
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14. Network pharmacological mechanism of Cinobufotalin against glioma.
Li C; Guo H; Wang C; Zhan W; Tan Q; Xie C; Sharma A; Sharma HS; Chen L; Zhang Z
Prog Brain Res; 2021; 265():119-137. PubMed ID: 34560920
[TBL] [Abstract] [Full Text] [Related]
15. Fermitin family member 2 promotes melanoma progression by enhancing the binding of p-α-Pix to rac1 to activate the MAPK pathway.
Huang S; Deng W; Wang P; Yan Y; Xie C; Cao X; Chen M; Zhang C; Shi D; Dong Y; Cheng P; Xu H; Zhu W; Hu Z; Tang B; Zhu J
Oncogene; 2021 Sep; 40(37):5626-5638. PubMed ID: 34321603
[TBL] [Abstract] [Full Text] [Related]
16. A new synthetic antitumor naphthoquinone induces ROS-mediated apoptosis with activation of the JNK and p38 signaling pathways.
de Almeida PDO; Dos Santos Barbosa Jobim G; Dos Santos Ferreira CC; Rocha Bernardes L; Dias RB; Schlaepfer Sales CB; Valverde LF; Rocha CAG; Soares MBP; Bezerra DP; de Carvalho da Silva F; Cardoso MFDC; Ferreira VF; Brito LF; Pires de Sousa L; de Vasconcellos MC; Lima ES
Chem Biol Interact; 2021 Jul; 343():109444. PubMed ID: 33939975
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17. Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma.
Afanasyeva EA; Gartlgruber M; Ryl T; Decaesteker B; Denecker G; Mönke G; Toprak UH; Florez A; Torkov A; Dreidax D; Herrmann C; Okonechnikov K; Ek S; Sharma AK; Sagulenko V; Speleman F; Henrich KO; Westermann F
Life Sci Alliance; 2021 May; 4(5):. PubMed ID: 33658318
[TBL] [Abstract] [Full Text] [Related]
18. Glioma-Derived TSP2 Promotes Excitatory Synapse Formation and Results in Hyperexcitability in the Peritumoral Cortex of Glioma.
Wang YH; Huang TL; Chen X; Yu SX; Li W; Chen T; Li Y; Kuang YQ; Shu HF
J Neuropathol Exp Neurol; 2021 Jan; 80(2):137-149. PubMed ID: 33382873
[TBL] [Abstract] [Full Text] [Related]
19. Sphingosine‑1‑phosphate analogue FTY720 exhibits a potent anti‑proliferative effect on glioblastoma cells.
Kolodziej MA; Al Barim B; Nagl J; Weigand MA; Uhl E; Uhle F; Di Fazio P; Schwarm FP; Stein M
Int J Oncol; 2020 Oct; 57(4):1039-1046. PubMed ID: 32945397
[TBL] [Abstract] [Full Text] [Related]
20. Natural History of Growing Sporadic Vestibular Schwannomas: An Argument for Continued Observation Despite Documented Growth in Select Cases.
Marinelli JP; Lees KA; Lohse CM; Driscoll CLW; Neff BA; Link MJ; Van Gompel JJ; Carlson ML
Otol Neurotol; 2020 Oct; 41(9):e1149-e1153. PubMed ID: 32925859
[TBL] [Abstract] [Full Text] [Related]
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