BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND SETD2, ENSG00000181555, 29072
38 results:

  • 1. Clinical and Genomic Predictors of Adverse Events in Newly Diagnosed Glioblastoma.
    Lim-Fat MJ; Iorgulescu JB; Rahman R; Bhave V; Muzikansky A; Woodward E; Whorral S; Allen M; Touat M; Li X; Xy G; Patel J; Gerstner ER; Kalpathy-Cramer J; Youssef G; Chukwueke U; McFaline-Figueroa JR; Nayak L; Lee EQ; Reardon DA; Beroukhim R; Huang RY; Bi WL; Ligon KL; Wen PY
    Clin Cancer Res; 2024 Apr; 30(7):1327-1337. PubMed ID: 38252427
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
    Hadad S; Gupta R; Oberheim Bush NA; Taylor JW; Villanueva-Meyer JE; Young JS; Wu J; Ravindranathan A; Zhang Y; Warrier G; McCoy L; Shai A; Pekmezci M; Perry A; Bollen AW; Phillips JJ; Braunstein SE; Raleigh DR; Theodosopoulos P; Aghi MK; Chang EF; Hervey-Jumper SL; Costello JF; de Groot J; Butowski NA; Clarke JL; Chang SM; Berger MS; Molinaro AM; Solomon DA
    Acta Neuropathol; 2023 Dec; 147(1):3. PubMed ID: 38079020
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Association of the Genomic Profile of Medullary Thyroid Carcinoma with tumor Characteristics and Clinical Outcomes in an International Multicenter Study.
    Xu B; Viswanathan K; Ahadi MS; Ahmadi S; Alzumaili B; Bani MA; Baudin E; Behrman DB; Capelletti M; Chau NG; Chiarucci F; Chou A; Clifton-Bligh R; Coluccelli S; de Biase D; De Leo A; Dogan S; Fagin JA; Fuchs TL; Glover AR; Hadoux J; Lacroix L; Lamartina L; Lubin DJ; Luxford C; Magliocca K; Maloberti T; Mohanty AS; Najdawi F; Nigam A; Papachristos AJ; Repaci A; Robinson B; Scoazec JY; Shi Q; Sidhu S; Solaroli E; Sywak M; Tuttle RM; Untch B; Barletta JA; Al Ghuzlan A; Gill AJ; Ghossein R; Tallini G; Ganly I
    Thyroid; 2024 Feb; 34(2):167-176. PubMed ID: 37842841
    [No Abstract]    [Full Text] [Related]  

  • 4. setd2 controls m6A modification of transcriptome and regulates the molecular oncogenesis of glioma.
    Kumari S; Singh M; Kumar S; Muthuswamy S
    Med Oncol; 2023 Jul; 40(9):249. PubMed ID: 37490181
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Integrated Genomic and Clinicopathologic Approach Distinguishes Pancreatic Grade 3 Neuroendocrine tumor From Neuroendocrine Carcinoma and Identifies a Subset With Molecular Overlap.
    Umetsu SE; Kakar S; Basturk O; Kim GE; Chatterjee D; Wen KW; Hale G; Shafizadeh N; Cho SJ; Whitman J; Gill RM; Jones KD; Navale P; Bergsland E; Klimstra D; Joseph NM
    Mod Pathol; 2023 Mar; 36(3):100065. PubMed ID: 36788102
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Individualized combination therapies based on whole-exome sequencing displayed significant clinical benefits in a glioblastoma patient with secondary osteosarcoma: case report and genetic characterization.
    Yi GZ; Zhu TC; Que TS; Li ZY; Huang GL
    BMC Neurol; 2022 Oct; 22(1):390. PubMed ID: 36271359
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes.
    Bai J; Shi J; Zhang Y; Li C; Xiong Y; Koka H; Wang D; Zhang T; Song L; Luo W; Zhu B; Hicks B; Hutchinson A; Kirk E; Troester MA; Li M; Shen Y; Ma T; Wang J; Liu X; Wang S; Gui S; McMaster ML; Chanock SJ; Parry DM; Goldstein AM; Yang XR
    Clin Cancer Res; 2023 Jan; 29(1):261-270. PubMed ID: 36260525
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Oncohistone interactome profiling uncovers contrasting oncogenic mechanisms and identifies potential therapeutic targets in high grade glioma.
    Siddaway R; Canty L; Pajovic S; Milos S; Coyaud E; Sbergio SG; Vadivel Anguraj AK; Lubanszky E; Yun HY; Portante A; Carette S; Zhang C; Moran MF; Raught B; Campos EI; Hawkins C
    Acta Neuropathol; 2022 Nov; 144(5):1027-1048. PubMed ID: 36070144
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. setd2 Palmitoylation Mediated by ZDHHC16 in Epidermal Growth Factor Receptor-Mutated Glioblastoma Promotes Ionizing Radiation-Induced DNA Damage.
    Fan X; Sun S; Yang H; Ma H; Zhao C; Niu W; Fan J; Fang Z; Chen X
    Int J Radiat Oncol Biol Phys; 2022 Jul; 113(3):648-660. PubMed ID: 35192890
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms.
    Venizelos A; Elvebakken H; Perren A; Nikolaienko O; Deng W; Lothe IMB; Couvelard A; Hjortland GO; Sundlöv A; Svensson J; Garresori H; Kersten C; Hofsli E; Detlefsen S; Krogh M; Sorbye H; Knappskog S
    Endocr Relat Cancer; 2021 Nov; 29(1):1-14. PubMed ID: 34647903
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Pro-inflammatory and proliferative microglia drive progression of glioblastoma.
    Liu H; Sun Y; Zhang Q; Jin W; Gordon RE; Zhang Y; Wang J; Sun C; Wang ZJ; Qi X; Zhang J; Huang B; Gui Q; Yuan H; Chen L; Ma X; Fang C; Liu YQ; Yu X; Feng S
    Cell Rep; 2021 Sep; 36(11):109718. PubMed ID: 34525361
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Sweat-gland carcinoma with neuroendocrine differentiation (SCAND): a clinicopathologic study of 13 cases with genetic analysis.
    Goto K; Kukita Y; Honma K; Ohike N; Komori T; Ishida Y; Ishikawa M; Nakatsuka T; Fumita S; Nakagawa K; Okabayashi A; Iwahashi Y; Tanino T; Kikuchi K; Kawahara Y; Hishima T; Uehara J; Oishi T; Isei T
    Mod Pathol; 2022 Jan; 35(1):33-43. PubMed ID: 34518631
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Histone Mark Profiling in Pediatric Astrocytomas Reveals Prognostic Significance of H3K9 Trimethylation and Histone Methyltransferase SUV39H1.
    Klonou A; Korkolopoulou P; Gargalionis AN; Kanakoglou DS; Katifelis H; Gazouli M; Chlamydas S; Mitsios A; Kalamatianos T; Stranjalis G; Themistocleous MS; Papavassiliou KA; Sgouros S; Papavassiliou AG; Piperi C
    Neurotherapeutics; 2021 Jul; 18(3):2073-2090. PubMed ID: 34296393
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells.
    Huang TY; Piunti A; Qi J; Morgan M; Bartom E; Shilatifard A; Saratsis AM
    Acta Neuropathol Commun; 2020 Dec; 8(1):219. PubMed ID: 33287886
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Histone Lysine-to-Methionine Mutation as Anticancer Drug Target.
    Yang J; Qiu Q; Chen L
    Adv Exp Med Biol; 2021; 1283():85-96. PubMed ID: 33155140
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Histone H3G34 Mutation in Brain and Bone tumors.
    Qiu L; Han J
    Adv Exp Med Biol; 2021; 1283():63-71. PubMed ID: 33155138
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.
    Jain SU; Khazaei S; Marchione DM; Lundgren SM; Wang X; Weinberg DN; Deshmukh S; Juretic N; Lu C; Allis CD; Garcia BA; Jabado N; Lewis PW
    Proc Natl Acad Sci U S A; 2020 Nov; 117(44):27354-27364. PubMed ID: 33067396
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Chromosome 3p loss of heterozygosity and reduced expression of H3K36me3 correlate with longer relapse-free survival in sacral conventional chordoma.
    Zhu GG; Ramirez D; Chen W; Lu C; Wang L; Frosina D; Jungbluth A; Ntiamoah P; Nafa K; Boland PJ; Hameed MR
    Hum Pathol; 2020 Oct; 104():73-83. PubMed ID: 32795465
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma.
    Liu SJ; Magill ST; Vasudevan HN; Hilz S; Villanueva-Meyer JE; Lastella S; Daggubati V; Spatz J; Choudhury A; Orr BA; Demaree B; Seo K; Ferris SP; Abate AR; Oberheim Bush NA; Bollen AW; McDermott MW; Costello JF; Raleigh DR
    Cell Rep; 2020 Feb; 30(5):1300-1309.e5. PubMed ID: 32023450
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Specific Genomic Alterations in High-Grade Pulmonary Neuroendocrine Tumours with Carcinoid Morphology.
    Cros J; Théou-Anton N; Gounant V; Nicolle R; Reyes C; Humez S; Hescot S; Thomas de Montpréville V; Guyétant S; Scoazec JY; Guyard A; de Mestier L; Brosseau S; Mordant P; Castier Y; Gentien D; Ruszniewski P; Zalcman G; Couvelard A; Cazes A
    Neuroendocrinology; 2021; 111(1-2):158-169. PubMed ID: 32015233
    [TBL] [Abstract] [Full Text] [Related]  


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