BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND SMO, Q99835, 6608, ENSG00000128602, SMOH, Gx
167 results:

  • 1. [En1 promotes cell proliferation and migration via Hedgehog signaling pathway in esophageal squamous cell carcinoma].
    Zhao N; Gong TY; Wei ZC; Cong J; Liu ZH; Chen HY
    Zhonghua Zhong Liu Za Zhi; 2024 Feb; 46(2):99-107. PubMed ID: 38418183
    [No Abstract]    [Full Text] [Related]  

  • 2. Arsenic Trioxide inhibits Activation of Hedgehog Pathway in Human Neuroblastoma cell Line SK-N-BE(2) Independent of Itraconazole.
    Liu X; Wang Z; Xiong X; Li C; Wu Y; Su M; Yang S; Zeng M; Weng W; Huang K; Zhou D; Fang J; Xu L; Li P; Zhu Y; Qiu K; Ma Y; Lei J; Li Y
    Anticancer Agents Med Chem; 2023; 23(20):2217-2224. PubMed ID: 37888819
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant smoothened and GLI into Glioma Primary Cilia.
    Shi P; Tian J; Mallinger JC; Ling D; Deleyrolle LP; McIntyre JC; Caspary T; Breunig JJ; Sarkisian MR
    Cells; 2023 Sep; 12(19):. PubMed ID: 37830570
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Intraventricular SHH inhibition proves efficient in SHH medulloblastoma mouse model and prevents systemic side effects.
    Kresbach C; Holst L; Schoof M; Leven T; Göbel C; Neyazi S; Tischendorf J; Loose C; Wrzeszcz A; Yorgan T; Rutkowski S; Schüller U
    Neuro Oncol; 2024 Apr; 26(4):609-622. PubMed ID: 37767814
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Assessing the genetic risk of nodular melanoma using a candidate gene approach.
    Stark MS; Sturm RA; Pan Y; Smit DJ; Kommajosyula V; Lee KJ; Jagirdar K; McLean C; Duffy DL; Soyer HP; Mar VJ
    Br J Dermatol; 2024 Jan; 190(2):199-206. PubMed ID: 37766469
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. smo-CRISPR-mediated apoptosis in CD133-targeted cancer stem cells and tumor growth inhibition.
    Pandey S; Lee M; Lim J; Park S; Choung YH; Kim JE; Garg P; Chung JH
    J Control Release; 2023 May; 357():94-108. PubMed ID: 36931470
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. The Hedgehog/GLI signaling pathway activates transcription of Slug (Snail2) in melanoma cells.
    Horák P; Kreisingerová K; Réda J; Ondrušová L; Balko J; Vachtenheim J; Žáková P; Vachtenheim J
    Oncol Rep; 2023 Apr; 49(4):. PubMed ID: 36866769
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. circRNA-smo upregulates CEP85 to promote proliferation and migration of glioblastoma via sponging miR-326.
    Wu B; Xia L; Zhang S; Jin K; Li L; Sun C; Xia T; Chen G
    Histol Histopathol; 2023 Nov; 38(11):1307-1319. PubMed ID: 36718820
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than 2 subgroups.
    Tonn S; Korshunov A; Obrecht D; Sill M; Spohn M; von Hoff K; Milde T; Pietsch T; Goschzik T; Bison B; Juhnke BO; Struve N; Sturm D; Sahm F; Bockmayr M; Friedrich C; von Bueren AO; Gerber NU; Benesch M; Jones DTW; Kool M; Wefers AK; Schüller U; Pfister SM; Rutkowski S; Mynarek M
    Neuro Oncol; 2023 Aug; 25(8):1518-1529. PubMed ID: 36715306
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth.
    Cleveland AH; Malawsky D; Churiwal M; Rodriguez C; Reed F; Schniederjan M; Velazquez Vega JE; Davis I; Gershon TR
    Acta Neuropathol Commun; 2023 Jan; 11(1):8. PubMed ID: 36635771
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449.
    Sloan AE; Nock CJ; Ye X; Buerki R; Chang S; Lesser G; Norden A; Cloughesy T; Olson J; Kerstetter-Fogle A; Rich J; Fisher J; Desideri S; Takebe N; Timmer W; Grossman S; Prados M
    J Neurooncol; 2023 Jan; 161(1):33-43. PubMed ID: 36581779
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Systematic analysis of cilia characteristics and Hedgehog signaling in five immortal cell lines.
    Gómez AE; Christman AK; Van De Weghe JC; Finn M; Doherty D
    PLoS One; 2022; 17(12):e0266433. PubMed ID: 36580465
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli.
    Huang W; Liu H; Tan W; Wang J
    Med Oncol; 2022 Sep; 39(12):188. PubMed ID: 36071246
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog-Dependent tumor Growth.
    Yang F; Rodriguez-Blanco J; Long J; Swiderska-Syn M; Wynn DT; Li B; Shen C; Nayak A; Ban Y; Sun X; Suter RK; McCrea HJ; Capobianco AJ; Ayad NG; Robbins DJ
    Mol Cancer Res; 2022 Nov; 20(11):1598-1610. PubMed ID: 35925047
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Noncanonical activation of GLI signaling in SOX2
    Swiderska-Syn M; Mir-Pedrol J; Oles A; Schleuger O; Salvador AD; Greiner SM; Seward C; Yang F; Babcock BR; Shen C; Wynn DT; Sanchez-Mejias A; Gershon TR; Martin V; McCrea HJ; Lindsey KG; Krieg C; Rodriguez-Blanco J
    Sci Adv; 2022 Jul; 8(29):eabj9138. PubMed ID: 35857834
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Curcumin analogue BDDD-721 exhibits more potent anticancer effects than curcumin on medulloblastoma by targeting Shh/Gli1 signaling pathway.
    Gong W; Zhao W; Liu G; Shi L; Zhao X
    Aging (Albany NY); 2022 Jul; 14(13):5464-5477. PubMed ID: 35802536
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in supratentorial ependymoma.
    de Almeida Magalhães T; Alencastro Veiga Cruzeiro G; Ribeiro de Sousa G; Englinger B; Fernando Peinado Nagano L; Ancliffe M; Rodrigues da Silva K; Jiang L; Gojo J; Cherry Liu Y; Carline B; Kuchibhotla M; Pinto Saggioro F; Kazue Nagahashi Marie S; Mieko Oba-Shinjo S; Andres Yunes J; Gomes de Paula Queiroz R; Alberto Scrideli C; Endersby R; Filbin MG; Silva Borges K; Salic A; Gonzaga Tone L; Valera ET
    Neuro Oncol; 2023 Jan; 25(1):185-198. PubMed ID: 35640920
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Targeting AKT and CK2 represents a novel therapeutic strategy for smo constitutive activation-driven medulloblastoma.
    Yao YL; Wang YX; Yang FC; Wang C; Mao M; Gai QJ; He J; Qin Y; Yao XX; Lan X; Zhu J; Lu HM; Zeng H; Yao XH; Bian XW; Wang Y
    CNS Neurosci Ther; 2022 Jul; 28(7):1033-1044. PubMed ID: 35419951
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Exosomal microRNAs induce tumor-associated macrophages via PPARγ during tumor progression in SHH medulloblastoma.
    Zhu L; Yang Y; Li H; Xu L; You H; Liu Y; Liu Z; Liu X; Zheng D; Bie J; Li J; Song C; Yang B; Luo J; Chang Q
    Cancer Lett; 2022 Jun; 535():215630. PubMed ID: 35304257
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. [Medulloblastoma].
    Kanemura Y
    No Shinkei Geka; 2022 Jan; 50(1):73-90. PubMed ID: 35169088
    [TBL] [Abstract] [Full Text] [Related]  


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