BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND SMO, Q99835, 6608, ENSG00000128602, SMOH, Gx AND Prognosis
26 results:

  • 1. [En1 promotes cell proliferation and migration via Hedgehog signaling pathway in esophageal squamous cell carcinoma].
    Zhao N; Gong TY; Wei ZC; Cong J; Liu ZH; Chen HY
    Zhonghua Zhong Liu Za Zhi; 2024 Feb; 46(2):99-107. PubMed ID: 38418183
    [No Abstract]    [Full Text] [Related]  

  • 2. [Medulloblastoma].
    Kanemura Y
    No Shinkei Geka; 2022 Jan; 50(1):73-90. PubMed ID: 35169088
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. GLI-1 polymorphisms of Hedgehog pathway as novel risk and prognostic biomarkers in melanoma patients.
    Dunjic M; Lukic N; Djordjevic B; Uzelac B; Ostojic N; Supic G
    Melanoma Res; 2022 Feb; 32(1):11-17. PubMed ID: 34939981
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. G-protein-coupled receptors as therapeutic targets for glioblastoma.
    Byrne KF; Pal A; Curtin JF; Stephens JC; Kinsella GK
    Drug Discov Today; 2021 Dec; 26(12):2858-2870. PubMed ID: 34271165
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Identification of Clinical Relevant Molecular Subtypes of Pheochromocytoma.
    Saddozai UAK; Wang F; Akbar MU; Zhang L; An Y; Zhu W; Xie L; Li Y; Ji X; Guo X
    Front Endocrinol (Lausanne); 2021; 12():605797. PubMed ID: 34234737
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile.
    Malawsky DS; Weir SJ; Ocasio JK; Babcock B; Dismuke T; Cleveland AH; Donson AM; Vibhakar R; Wilhelmsen K; Gershon TR
    Commun Biol; 2021 May; 4(1):616. PubMed ID: 34021242
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma.
    Pietrobono S; Gaudio E; Gagliardi S; Zitani M; Carrassa L; Migliorini F; Petricci E; Manetti F; Makukhin N; Bond AG; Paradise BD; Ciulli A; Fernandez-Zapico ME; Bertoni F; Stecca B
    Oncogene; 2021 Jun; 40(22):3799-3814. PubMed ID: 33958721
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Integrated molecular analysis of adult sonic hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator.
    Korshunov A; Okonechnikov K; Stichel D; Ryzhova M; Schrimpf D; Sahm F; Sievers P; Absalyamova O; Zheludkova O; Golanov A; Jones DTW; Pfister SM; von Deimling A; Kool M
    Neuro Oncol; 2021 Sep; 23(9):1576-1585. PubMed ID: 33589929
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Genetic landscape and ligand-dependent activation of sonic hedgehog-Gli1 signaling in chordomas: a novel therapeutic target.
    Yang C; Yong L; Liang C; Li Y; Ma Y; Wei F; Jiang L; Zhou H; He G; Pan X; Hai B; Wu J; Xu Y; Liu Z; Liu X
    Oncogene; 2020 Jun; 39(24):4711-4727. PubMed ID: 32404987
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. smoothened Promotes Glioblastoma Radiation Resistance Via Activating USP3-Mediated Claspin Deubiquitination.
    Tu Y; Chen Z; Zhao P; Sun G; Bao Z; Chao H; Fan L; Li C; You Y; Qu Y; Chen Y; Ji J
    Clin Cancer Res; 2020 Apr; 26(7):1749-1762. PubMed ID: 31900278
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. GX15-070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma.
    Cournoyer S; Addioui A; Belounis A; Beaunoyer M; Nyalendo C; Le Gall R; Teira P; Haddad E; Vassal G; Sartelet H
    BMC Cancer; 2019 Oct; 19(1):1018. PubMed ID: 31664947
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Principles of tumorigenesis and emerging molecular drivers of SHH-activated medulloblastomas.
    Menyhárt O; Győrffy B
    Ann Clin Transl Neurol; 2019 May; 6(5):990-1005. PubMed ID: 31139698
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Molecular characterization of medulloblastomas with extensive nodularity (MBEN).
    Korshunov A; Sahm F; Stichel D; Schrimpf D; Ryzhova M; Zheludkova O; Golanov A; Lichter P; Jones DTW; von Deimling A; Pfister SM; Kool M
    Acta Neuropathol; 2018 Aug; 136(2):303-313. PubMed ID: 29569031
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Association of expression of the hedgehog signal with Merkel cell polyomavirus infection and prognosis of Merkel cell carcinoma.
    Kuromi T; Matsushita M; Iwasaki T; Nonaka D; Kuwamoto S; Nagata K; Kato M; Akizuki G; Kitamura Y; Hayashi K
    Hum Pathol; 2017 Nov; 69():8-14. PubMed ID: 28551328
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Negative prognostic effect of low nuclear GLI1 expression in glioblastomas.
    Kim Y; Do IG; Hong M; Suh YL
    J Neurooncol; 2017 May; 133(1):69-76. PubMed ID: 28417299
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. smoothened is a poor prognosis factor and a potential therapeutic target in glioma.
    Tu Y; Niu M; Xie P; Yue C; Liu N; Qi Z; Gao S; Liu H; Shi Q; Yu R; Liu X
    Sci Rep; 2017 Feb; 7():42630. PubMed ID: 28195165
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy.
    Paret C; Theruvath J; Russo A; Kron B; El Malki K; Lehmann N; Wingerter A; Neu MA; Gerhold-Ay A; Wagner W; Sommer C; Pietsch T; Seidmann L; Faber J
    Oncotarget; 2016 Dec; 7(50):83378-83391. PubMed ID: 27825128
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma.
    Andrade AF; Borges KS; Suazo VK; Geron L; Corrêa CA; Castro-Gamero AM; de Vasconcelos EJ; de Oliveira RS; Neder L; Yunes JA; Dos Santos Aguiar S; Scrideli CA; Tone LG
    Invest New Drugs; 2017 Feb; 35(1):26-36. PubMed ID: 27785591
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group.
    Vollbrecht C; Werner R; Walter RF; Christoph DC; Heukamp LC; Peifer M; Hirsch B; Burbat L; Mairinger T; Schmid KW; Wohlschlaeger J; Mairinger FD
    Br J Cancer; 2015 Dec; 113(12):1704-11. PubMed ID: 26645239
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by Honokiol in glioblastoma multiforme cells.
    Lai IC; Shih PH; Yao CJ; Yeh CT; Wang-Peng J; Lui TN; Chuang SE; Hu TS; Lai TY; Lai GM
    PLoS One; 2015; 10(3):e0114830. PubMed ID: 25763821
    [TBL] [Abstract] [Full Text] [Related]  


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