Terms: = Germ cell tumor AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS AND Treatment
22 results:
1. Real-World comprehensive genomic profiling data for diagnostic clarity in pulmonary Large-cell neuroendocrine carcinoma.
Burns L; Tukachinsky H; Raskina K; Huang RSP; Schrock AB; Sands J; Kulke MH; Oxnard GR; Tapan U
Lung Cancer; 2024 Feb; 188():107454. PubMed ID: 38159439
[TBL] [Abstract] [Full Text] [Related]
2. The Unmet Diagnostic and treatment Needs in Large cell Neuroendocrine Carcinoma of the Lung.
Buium C; Negru S; Ionescu DN; Dediu M
Curr Oncol; 2023 Jul; 30(8):7218-7228. PubMed ID: 37623004
[TBL] [Abstract] [Full Text] [Related]
3. Integrative Analysis of a Large Real-World Cohort of Small cell Lung Cancer Identifies Distinct Genetic Subtypes and Insights into Histologic Transformation.
Sivakumar S; Moore JA; Montesion M; Sharaf R; Lin DI; Colón CI; Fleishmann Z; Ebot EM; Newberg JY; Mills JM; Hegde PS; Pan Q; Dowlati A; Frampton GM; Sage J; Lovly CM
Cancer Discov; 2023 Jul; 13(7):1572-1591. PubMed ID: 37062002
[TBL] [Abstract] [Full Text] [Related]
4. Immune Checkpoint Blockade Outcome in Small-cell Lung Cancer and Its Relationship With Retinoblastoma Mutation Status and Function.
Dowlati A; Abbas A; Chan T; Henick B; Wang X; Doshi P; Fu P; Patel J; Kuo F; Chang H; Balli D
JCO Precis Oncol; 2022 Aug; 6():e2200257. PubMed ID: 36044718
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5. HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma.
Sriramareddy SN; Faião-Flores F; Emmons MF; Saha B; Chellappan S; Wyatt C; Smalley I; Licht JD; Durante MA; Harbour JW; Smalley KSM
Cancer Gene Ther; 2022 Dec; 29(12):1840-1846. PubMed ID: 35332245
[TBL] [Abstract] [Full Text] [Related]
6. The protein kinase lkb1 promotes self-renewal and blocks invasiveness in glioblastoma.
Caja L; Dadras MS; Mezheyeuski A; Rodrigues-Junior DM; Liu S; Webb AT; Gomez-Puerto MC; Ten Dijke P; Heldin CH; Moustakas A
J Cell Physiol; 2022 Jan; 237(1):743-762. PubMed ID: 34350982
[TBL] [Abstract] [Full Text] [Related]
7. TTF-1 and c-MYC-defined Phenotypes of Large cell Neuroendocrine Carcinoma and Delta-like Protein 3 Expression for treatment Selection.
Miyagawa-Hayashino A; Okada S; Takeda-Miyata N; Takashima Y; Yamada T; Takemura Y; Uchino J; Inoue M; Takayama K; Konishi E
Appl Immunohistochem Mol Morphol; 2021 Apr; 29(4):313-320. PubMed ID: 33031101
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8. A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma.
Vashisht Gopal YN; Gammon S; Prasad R; Knighton B; Pisaneschi F; Roszik J; Feng N; Johnson S; Pramanik S; Sudderth J; Sui D; Hudgens C; Fischer GM; Deng W; Reuben A; Peng W; Wang J; McQuade JL; Tetzlaff MT; Di Francesco ME; Marszalek J; Piwnica-Worms D; DeBerardinis RJ; Davies MA
Clin Cancer Res; 2019 Nov; 25(21):6429-6442. PubMed ID: 31439581
[TBL] [Abstract] [Full Text] [Related]
9. Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma.
Afzal MZ; Mercado RR; Shirai K
J Immunother Cancer; 2018 Jul; 6(1):64. PubMed ID: 29966520
[TBL] [Abstract] [Full Text] [Related]
10. Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.
George J; Walter V; Peifer M; Alexandrov LB; Seidel D; Leenders F; Maas L; Müller C; Dahmen I; Delhomme TM; Ardin M; Leblay N; Byrnes G; Sun R; De Reynies A; McLeer-Florin A; Bosco G; Malchers F; Menon R; Altmüller J; Becker C; Nürnberg P; Achter V; Lang U; Schneider PM; Bogus M; Soloway MG; Wilkerson MD; Cun Y; McKay JD; Moro-Sibilot D; Brambilla CG; Lantuejoul S; Lemaitre N; Soltermann A; Weder W; Tischler V; Brustugun OT; Lund-Iversen M; Helland Å; Solberg S; Ansén S; Wright G; Solomon B; Roz L; Pastorino U; Petersen I; Clement JH; Sänger J; Wolf J; Vingron M; Zander T; Perner S; Travis WD; Haas SA; Olivier M; Foll M; Büttner R; Hayes DN; Brambilla E; Fernandez-Cuesta L; Thomas RK
Nat Commun; 2018 Mar; 9(1):1048. PubMed ID: 29535388
[TBL] [Abstract] [Full Text] [Related]
11. Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy treatment Outcome.
Derks JL; Leblay N; Thunnissen E; van Suylen RJ; den Bakker M; Groen HJM; Smit EF; Damhuis R; van den Broek EC; Charbrier A; Foll M; McKay JD; Fernandez-Cuesta L; Speel EM; Dingemans AC;
Clin Cancer Res; 2018 Jan; 24(1):33-42. PubMed ID: 29066508
[No Abstract] [Full Text] [Related]
12. Neuroblastoma cells undergo transcriptomic alterations upon dissemination into the bone marrow and subsequent tumor progression.
Rifatbegovic F; Frech C; Abbasi MR; Taschner-Mandl S; Weiss T; Schmidt WM; Schmidt I; Ladenstein R; Ambros IM; Ambros PF
Int J Cancer; 2018 Jan; 142(2):297-307. PubMed ID: 28921546
[TBL] [Abstract] [Full Text] [Related]
13. Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma.
Olvedy M; Tisserand JC; Luciani F; Boeckx B; Wouters J; Lopez S; Rambow F; Aibar S; Thienpont B; Barra J; Köhler C; Radaelli E; Tartare-Deckert S; Aerts S; Dubreuil P; van den Oord JJ; Lambrechts D; De Sepulveda P; Marine JC
J Clin Invest; 2017 Jun; 127(6):2310-2325. PubMed ID: 28463229
[TBL] [Abstract] [Full Text] [Related]
14. miRNA-451 inhibits glioma cell proliferation and invasion by downregulating glucose transporter 1.
Guo H; Nan Y; Zhen Y; Zhang Y; Guo L; Yu K; Huang Q; Zhong Y
Tumour Biol; 2016 Oct; 37(10):13751-13761. PubMed ID: 27476171
[TBL] [Abstract] [Full Text] [Related]
15. Valproic acid sensitizes human glioma cells to gefitinib-induced autophagy.
Chang CY; Li JR; Wu CC; Ou YC; Chen WY; Kuan YH; Wang WY; Chen CJ
IUBMB Life; 2015 Nov; 67(11):869-79. PubMed ID: 26488897
[TBL] [Abstract] [Full Text] [Related]
16. Identification of Unique, Heterozygous germline Mutation, stk11 (p.F354L), in a Child with an Encapsulated Follicular Variant of Papillary Thyroid Carcinoma within Six Months of Completing treatment for Neuroblastoma.
Buryk MA; Picarsic JL; Creary SE; Shaw PH; Simons JP; Deutsch M; Monaco SE; Nikiforov YE; Witchel SF
Pediatr Dev Pathol; 2015; 18(4):318-23. PubMed ID: 25751324
[TBL] [Abstract] [Full Text] [Related]
17. Probucol suppresses human glioma cell proliferation in vitro via ROS production and lkb1-AMPK activation.
Jiang YS; Lei JA; Feng F; Liang QM; Wang FR
Acta Pharmacol Sin; 2014 Dec; 35(12):1556-65. PubMed ID: 25399650
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18. AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway.
Petti C; Vegetti C; Molla A; Bersani I; Cleris L; Mustard KJ; Formelli F; Hardie GD; Sensi M; Anichini A
Melanoma Res; 2012 Oct; 22(5):341-50. PubMed ID: 22588166
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19. Alterations of the lkb1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Tajiri M; Wakabayashi N; Tsujino M; Fujii M; Okabe K; Honoki K; Tsujiuchi T
Pathobiology; 2010; 77(4):225-9. PubMed ID: 20616618
[TBL] [Abstract] [Full Text] [Related]
20. In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Ikediobi ON; Reimers M; Durinck S; Blower PE; Futreal AP; Stratton MR; Weinstein JN
Mol Cancer Ther; 2008 Jun; 7(6):1337-46. PubMed ID: 18524847
[TBL] [Abstract] [Full Text] [Related]
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