BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND TET2, Q6N021, MGC125715, KIAA1546, FLJ20032, ENSG00000168769, 54790
45 results:

  • 1. NSUN5/tet2-directed chromatin-associated RNA modification of 5-methylcytosine to 5-hydroxymethylcytosine governs glioma immune evasion.
    Wu R; Sun C; Chen X; Yang R; Luan Y; Zhao X; Yu P; Luo R; Hou Y; Tian R; Bian S; Li Y; Dong Y; Liu Q; Dai W; Fan Z; Yan R; Pan B; Feng S; Wu J; Chen F; Yang C; Wang H; Dai H; Shu M
    Proc Natl Acad Sci U S A; 2024 Apr; 121(14):e2321611121. PubMed ID: 38547058
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Characterization of a Preclinical In Vitro Model Derived from a SMARCA4-Mutated Sinonasal Teratocarcinosarcoma.
    Lorenzo-Guerra SL; Codina-Martínez H; Suárez-Fernández L; Cabal VN; García-Marín R; Riobello C; Vivanco B; Blanco-Lorenzo V; Sánchez-Fernández P; López F; Llorente JL; Hermsen MA
    Cells; 2023 Dec; 13(1):. PubMed ID: 38201285
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Functional tet2 gene polymorphisms increase the risk of neuroblastoma in Chinese children.
    Lin L; Wang B; Zhang X; Deng C; Zhou C; Zhu J; Wu H; He J
    IUBMB Life; 2024 Apr; 76(4):200-211. PubMed ID: 38014648
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.
    Homan CC; Drazer MW; Yu K; Lawrence DM; Feng J; Arriola-Martinez L; Pozsgai MJ; McNeely KE; Ha T; Venugopal P; Arts P; King-Smith SL; Cheah J; Armstrong M; Wang P; Bödör C; Cantor AB; Cazzola M; Degelman E; DiNardo CD; Duployez N; Favier R; Fröhling S; Rio-Machin A; Klco JM; Krämer A; Kurokawa M; Lee J; Malcovati L; Morgan NV; Natsoulis G; Owen C; Patel KP; Preudhomme C; Raslova H; Rienhoff H; Ripperger T; Schulte R; Tawana K; Velloso E; Yan B; Kim E; Sood R; Hsu AP; Holland SM; Phillips K; Poplawski NK; Babic M; Wei AH; Forsyth C; Mar Fan H; Lewis ID; Cooney J; Susman R; Fox LC; Blombery P; Singhal D; Hiwase D; Phipson B; Schreiber AW; Hahn CN; Scott HS; Liu P; Godley LA; Brown AL;
    Blood Adv; 2023 Oct; 7(20):6092-6107. PubMed ID: 37406166
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. MiR-10b-5p Impairs tet2-Mediated Inhibition of PD-L1 Transcription Thus Promoting Immune Evasion and tumor Progression in Glioblastoma.
    Du W; Chen D; Wei K; Yu D; Gan Z; Xu G; Yao G
    Tohoku J Exp Med; 2023 Jul; 260(3):205-214. PubMed ID: 37019647
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers.
    Gunn K; Myllykoski M; Cao JZ; Ahmed M; Huang B; Rouaisnel B; Diplas BH; Levitt MM; Looper R; Doench JG; Ligon KL; Kornblum HI; McBrayer SK; Yan H; Duy C; Godley LA; Koivunen P; Losman JA
    Cancer Discov; 2023 Jun; 13(6):1478-1497. PubMed ID: 36847506
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Whole-exome sequencing reveals genetic variants in low-risk and high-risk neuroblastoma.
    Altun Z; Yuan H; Baran B; Aktaş S; Sönmez EE; Küçük C; Olgun N
    Gene; 2023 Apr; 860():147233. PubMed ID: 36736507
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Vitamin C boosts DNA demethylation in tet2 germline mutation carriers.
    Taira A; Palin K; Kuosmanen A; Välimäki N; Kuittinen O; Kuismin O; Kaasinen E; Rajamäki K; Aaltonen LA
    Clin Epigenetics; 2023 Jan; 15(1):7. PubMed ID: 36639817
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. germline genetic biomarkers to stratify patients for personalized radiation treatment.
    Deichaite I; Hopper A; Krockenberger L; Sears TJ; Sutton L; Ray X; Sharabi A; Navon A; Sanghvi P; Carter H; Moiseenko V
    J Transl Med; 2022 Aug; 20(1):360. PubMed ID: 35962345
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.
    Piaggio F; Croce M; Reggiani F; Monti P; Bernardi C; Ambrosio M; Banelli B; Dogrusöz M; Jockers R; Bordo D; Puzone R; Viaggi S; Coviello D; Lanza FB; Bartolucci M; Petretto A; Mosci C; Gangemi R; van der Velden PA; Jager MJ; Pfeffer U; Amaro A
    Eur J Cancer; 2022 Jul; 170():27-41. PubMed ID: 35580369
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Sox2 induces glioblastoma cell stemness and tumor propagation by repressing tet2 and deregulating 5hmC and 5mC DNA modifications.
    Lopez-Bertoni H; Johnson A; Rui Y; Lal B; Sall S; Malloy M; Coulter JB; Lugo-Fagundo M; Shudir S; Khela H; Caputo C; Green JJ; Laterra J
    Signal Transduct Target Ther; 2022 Feb; 7(1):37. PubMed ID: 35136034
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Characterization of the CpG Island Hypermethylated Phenotype Subclass in Primary Melanomas.
    Conway K; Tsai YS; Edmiston SN; Parker JS; Parrish EA; Hao H; Kuan PF; Scott GA; Frank JS; Googe P; Ollila DW; Thomas NE
    J Invest Dermatol; 2022 Jul; 142(7):1869-1881.e10. PubMed ID: 34843679
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Comprehensive landscape and interference of clonal haematopoiesis mutations for liquid biopsy: A Chinese pan-cancer cohort.
    Xu E; Su K; Zhou Y; Gong L; Xuan Y; Liao M; Cao J; Li Y; Lu Y; Zhao Y; Chen F
    J Cell Mol Med; 2021 Nov; 25(21):10279-10290. PubMed ID: 34658138
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Ten-eleven translocation protein 1 modulates medulloblastoma progression.
    Kim H; Kang Y; Li Y; Chen L; Lin L; Johnson ND; Zhu D; Robinson MH; McSwain L; Barwick BG; Yuan X; Liao X; Zhao J; Zhang Z; Shu Q; Chen J; Allen EG; Kenney AM; Castellino RC; Van Meir EG; Conneely KN; Vertino PM; Jin P; Li J
    Genome Biol; 2021 Apr; 22(1):125. PubMed ID: 33926529
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Acute high folic acid treatment in SH-SY5Y cells with and without MTHFR function leads to gene expression changes in epigenetic modifying enzymes, changes in epigenetic marks, and changes in dendritic spine densities.
    Clark DF; Schmelz R; Rogers N; Smith NE; Shorter KR
    PLoS One; 2021; 16(1):e0245005. PubMed ID: 33411826
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Expression and prognostic characteristics of m
    Li X; Meng Y
    J Cell Mol Med; 2021 Feb; 25(3):1383-1393. PubMed ID: 33400376
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Differential expression of DNA methyltransferases and demethylases among the various testicular germ cell tumor subtypes.
    Lobo J; Guimarães R; Miranda-Gonçalves V; Monteiro-Reis S; Cantante M; Antunes L; Braga I; Maurício J; Looijenga LH; Jerónimo C; Henrique R
    Epigenomics; 2020 Sep; 12(18):1579-1592. PubMed ID: 32957806
    [No Abstract]    [Full Text] [Related]  

  • 18. Demethylation Status of Somatic DNA Extracted From Pituitary Neuroendocrine tumors Indicates Proliferative Behavior.
    Szabó B; Németh K; Mészáros K; Szücs N; Czirják S; Reiniger L; Rajnai H; Krencz I; Karászi K; Krokker L; Patócs A; Butz H
    J Clin Endocrinol Metab; 2020 Jun; 105(6):. PubMed ID: 32232382
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma.
    Han B; Meng X; Wu P; Li Z; Li S; Zhang Y; Zha C; Ye Q; Jiang C; Cai J; Jiang T
    Theranostics; 2020; 10(7):3351-3365. PubMed ID: 32194873
    [No Abstract]    [Full Text] [Related]  

  • 20. Clinical Utility of Next-Generation Sequencing in Acute Myeloid Leukemia.
    Yang F; Anekpuritanang T; Press RD
    Mol Diagn Ther; 2020 Feb; 24(1):1-13. PubMed ID: 31848884
    [TBL] [Abstract] [Full Text] [Related]  


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