BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND TOP2A, TOP2, TP2A
65 results:

  • 1. The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma.
    Shirai Y; Ueno T; Kojima S; Ikeuchi H; Kitada R; Koyama T; Takahashi F; Takahashi K; Ichimura K; Yoshida A; Sugino H; Mano H; Narita Y; Takahashi M; Kohsaka S
    J Neurooncol; 2024 Mar; 167(1):75-88. PubMed ID: 38363490
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Exploring the anti-glioma mechanism of the active components of Cortex Periplocae based on network pharmacology and iTRAQ proteomics in vitro.
    Huan J; You CP; Lu YC; Che FY
    Adv Clin Exp Med; 2023 Nov; 32(11):1279-1290. PubMed ID: 37901992
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Identification and verification of potential biomarkers in sertoli cell-only syndrome via bioinformatics analysis.
    Jiang Y; Yang X; Li L; Lv X; Wang R; Zhang H; Liu R
    Sci Rep; 2023 Jul; 13(1):12164. PubMed ID: 37500704
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Expression of microRNAs and their target genes in melanomas originating from gynecologic sites.
    DiVincenzo MJ; Angell CD; Suarez-Kelly LP; Ren C; Barricklow Z; Moufawad M; Fadda P; Yu L; Backes FJ; Ring K; Mills A; Slingluff C; Chung C; Gru AA; Carson WE
    PLoS One; 2023; 18(6):e0285804. PubMed ID: 37384650
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Targeted sequencing of cancer-related genes reveals a recurrent top2a variant which affects DNA binding and coincides with global transcriptional changes in glioblastoma.
    Gielniewski B; Poleszak K; Roura AJ; Szadkowska P; Jacek K; Krol SK; Guzik R; Wiechecka P; Maleszewska M; Kaza B; Marchel A; Czernicki T; Koziarski A; Zielinski G; Styk A; Kawecki M; Szczylik C; Czepko R; Banach M; Kaspera W; Szopa W; Bujko M; Czapski B; Zabek M; Iżycka-Świeszewska E; Kloc W; Nauman P; Cieslewicz J; Grajkowska W; Morosini N; Noushmehr H; Wojtas B; Kaminska B
    Int J Cancer; 2023 Sep; 153(5):1003-1015. PubMed ID: 37338006
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. An
    Özbek M; Toy HI; Oktay Y; Karakülah G; Suner A; Pavlopoulou A
    PeerJ; 2023; 11():e15096. PubMed ID: 36945359
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability.
    Luo Z; Xin D; Liao Y; Berry K; Ogurek S; Zhang F; Zhang L; Zhao C; Rao R; Dong X; Li H; Yu J; Lin Y; Huang G; Xu L; Xin M; Nishinakamura R; Yu J; Kool M; Pfister SM; Roussel MF; Zhou W; Weiss WA; Andreassen P; Lu QR
    Nat Commun; 2023 Feb; 14(1):762. PubMed ID: 36765089
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. top2a Expression in Pheochromocytoma and Abdominal Paraganglioma: a Marker of Poor Clinical Outcome?
    Solhusløkk Höse K; Stenman A; Svahn F; Larsson C; Juhlin CC
    Endocr Pathol; 2023 Mar; 34(1):129-141. PubMed ID: 36656469
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Glioma Subtypes Based on the Activity Changes of Immunologic and Hallmark Gene Sets in Cancer.
    Chen S
    Front Endocrinol (Lausanne); 2022; 13():879233. PubMed ID: 35774141
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Knockdown of NUSAP1 inhibits cell proliferation and invasion through downregulation of top2a in human glioblastoma.
    Hu Y; Xue Z; Qiu C; Feng Z; Qi Q; Wang J; Jin W; Zhong Z; Liu X; Li W; Zhang Q; Huang B; Chen A; Wang J; Yang N; Zhou W
    Cell Cycle; 2022 Sep; 21(17):1842-1855. PubMed ID: 35532155
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. PTEN loss drives resistance to the neddylation inhibitor MLN4924 in glioblastoma and can be overcome with top2a inhibitors.
    Ferdosi SR; Taylor B; Lee M; Tang N; Peng S; Bybee R; Reid G; Hartman L; Garcia-Mansfield K; Sharma R; Pirrotte P; Ma J; Parisian AD; Furnari F; Dhruv HD; Berens ME
    Neuro Oncol; 2022 Nov; 24(11):1857-1868. PubMed ID: 35305088
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. DNA topoisomerase II alpha promotes the metastatic characteristics of glioma cells by transcriptionally activating β-catenin.
    Liu Y; Ma J; Song JS; Zhou HY; Li JH; Luo C; Geng X; Zhao HX
    Bioengineered; 2022 Feb; 13(2):2207-2216. PubMed ID: 35012441
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. KMT2A-MAML2 rearrangement emerged and regressed during neuroblastoma therapy without leukemia after 12.8-year follow-up.
    Felix CA; Slater DJ; Davenport JW; Yu X; Gregory BD; Li MM; Rappaport EF; Cheung NV
    Pediatr Blood Cancer; 2022 Jan; 69(1):e29344. PubMed ID: 34550633
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Transcriptome analysis revealed CENPF associated with glioma prognosis.
    Zhang M; Zhang Q; Bai J; Zhao Z; Zhang J
    Math Biosci Eng; 2021 Mar; 18(3):2077-2096. PubMed ID: 33892537
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Analysis of intraoperative human brain tissue transcriptome reveals putative risk genes and altered molecular pathways in glioma-related seizures.
    Feyissa AM; Carrano A; Wang X; Allen M; Ertekin-Taner N; Dickson DW; Jentoft ME; Rosenfeld SS; Tatum WO; Ritaccio AL; Guerrero-Cázares H; Quiñones-Hinojosa A
    Epilepsy Res; 2021 Jul; 173():106618. PubMed ID: 33765507
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Circ‑top2a acts as a ceRNA for miR‑346 and contributes to glioma progression via the modulation of sushi domain‑containing 2.
    Sang J; Li X; Lv L; Zhang C; Zhang X; Li G
    Mol Med Rep; 2021 Apr; 23(4):. PubMed ID: 33537815
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Comparative analysis of transcriptomic profile, histology, and IDH mutation for classification of gliomas.
    Tran PMH; Tran LKH; Nechtman J; Dos Santos B; Purohit S; Satter KB; Dun B; Kolhe R; Sharma S; Bollag R; She JX
    Sci Rep; 2020 Nov; 10(1):20651. PubMed ID: 33244057
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Bioinformatics analysis of multi-omics data identifying molecular biomarker candidates and epigenetically regulatory targets associated with retinoblastoma.
    Zeng Y; He T; Liu J; Li Z; Xie F; Chen C; Xing Y
    Medicine (Baltimore); 2020 Nov; 99(47):e23314. PubMed ID: 33217867
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Identification of Differentially Expressed Genes and Signaling Pathways in Glioma by Integrated Bioinformatics Analysis.
    Xu C; Su W; Jiang X
    J Craniofac Surg; 2020; 31(8):2360-2363. PubMed ID: 33136891
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Gene regulation network analysis reveals core genes associated with survival in glioblastoma multiforme.
    Jiang L; Zhong M; Chen T; Zhu X; Yang H; Lv K
    J Cell Mol Med; 2020 Sep; 24(17):10075-10087. PubMed ID: 32696617
    [TBL] [Abstract] [Full Text] [Related]  


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