BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND TOP2A, TOP2, TP2A AND Prognosis
21 results:

  • 1. The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma.
    Shirai Y; Ueno T; Kojima S; Ikeuchi H; Kitada R; Koyama T; Takahashi F; Takahashi K; Ichimura K; Yoshida A; Sugino H; Mano H; Narita Y; Takahashi M; Kohsaka S
    J Neurooncol; 2024 Mar; 167(1):75-88. PubMed ID: 38363490
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Targeted sequencing of cancer-related genes reveals a recurrent top2a variant which affects DNA binding and coincides with global transcriptional changes in glioblastoma.
    Gielniewski B; Poleszak K; Roura AJ; Szadkowska P; Jacek K; Krol SK; Guzik R; Wiechecka P; Maleszewska M; Kaza B; Marchel A; Czernicki T; Koziarski A; Zielinski G; Styk A; Kawecki M; Szczylik C; Czepko R; Banach M; Kaspera W; Szopa W; Bujko M; Czapski B; Zabek M; Iżycka-Świeszewska E; Kloc W; Nauman P; Cieslewicz J; Grajkowska W; Morosini N; Noushmehr H; Wojtas B; Kaminska B
    Int J Cancer; 2023 Sep; 153(5):1003-1015. PubMed ID: 37338006
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. An
    Özbek M; Toy HI; Oktay Y; Karakülah G; Suner A; Pavlopoulou A
    PeerJ; 2023; 11():e15096. PubMed ID: 36945359
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability.
    Luo Z; Xin D; Liao Y; Berry K; Ogurek S; Zhang F; Zhang L; Zhao C; Rao R; Dong X; Li H; Yu J; Lin Y; Huang G; Xu L; Xin M; Nishinakamura R; Yu J; Kool M; Pfister SM; Roussel MF; Zhou W; Weiss WA; Andreassen P; Lu QR
    Nat Commun; 2023 Feb; 14(1):762. PubMed ID: 36765089
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Glioma Subtypes Based on the Activity Changes of Immunologic and Hallmark Gene Sets in Cancer.
    Chen S
    Front Endocrinol (Lausanne); 2022; 13():879233. PubMed ID: 35774141
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Transcriptome analysis revealed CENPF associated with glioma prognosis.
    Zhang M; Zhang Q; Bai J; Zhao Z; Zhang J
    Math Biosci Eng; 2021 Mar; 18(3):2077-2096. PubMed ID: 33892537
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Circ‑top2a acts as a ceRNA for miR‑346 and contributes to glioma progression via the modulation of sushi domain‑containing 2.
    Sang J; Li X; Lv L; Zhang C; Zhang X; Li G
    Mol Med Rep; 2021 Apr; 23(4):. PubMed ID: 33537815
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Comparative analysis of transcriptomic profile, histology, and IDH mutation for classification of gliomas.
    Tran PMH; Tran LKH; Nechtman J; Dos Santos B; Purohit S; Satter KB; Dun B; Kolhe R; Sharma S; Bollag R; She JX
    Sci Rep; 2020 Nov; 10(1):20651. PubMed ID: 33244057
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Gene regulation network analysis reveals core genes associated with survival in glioblastoma multiforme.
    Jiang L; Zhong M; Chen T; Zhu X; Yang H; Lv K
    J Cell Mol Med; 2020 Sep; 24(17):10075-10087. PubMed ID: 32696617
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Multivariate analysis reveals differentially expressed genes among distinct subtypes of diffuse astrocytic gliomas: diagnostic implications.
    González-García N; Nieto-Librero AB; Vital AL; Tao HJ; González-Tablas M; Otero Á; Galindo-Villardón P; Orfao A; Tabernero MD
    Sci Rep; 2020 Jul; 10(1):11270. PubMed ID: 32647207
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Screening for genes and subnetworks associated with atypical teratoid/rhabdoid tumors using bioinformatics analysis.
    Li G; Wang Y; Cai L; Zhou L
    Int J Neurosci; 2021 Apr; 131(4):319-326. PubMed ID: 32202192
    [No Abstract]    [Full Text] [Related]  

  • 12. Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine tumors.
    Scott AT; Weitz M; Breheny PJ; Ear PH; Darbro B; Brown BJ; Braun TA; Li G; Umesalma S; Kaemmer CA; Maharjan CK; Quelle DE; Bellizzi AM; Chandrasekharan C; Dillon JS; O'Dorisio TM; Howe JR
    Clin Cancer Res; 2020 Apr; 26(8):2011-2021. PubMed ID: 31937620
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Identification of Potential Biomarkers in Glioblastoma through Bioinformatic Analysis and Evaluating Their Prognostic Value.
    Zhou Y; Yang L; Zhang X; Chen R; Chen X; Tang W; Zhang M
    Biomed Res Int; 2019; 2019():6581576. PubMed ID: 31119182
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Identification of Driver Genes and Key Pathways of Ependymoma.
    Zhong S; Yan Q; Ge J; Dou G; Xu H; Zhao G
    Turk Neurosurg; 2024; 34(2):184-195. PubMed ID: 30649797
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The Inhibition of miR-144-3p on cell Proliferation and Metastasis by Targeting top2a in HCMV-Positive Glioblastoma cells.
    Song J; Ma Q; Hu M; Qian D; Wang B; He N
    Molecules; 2018 Dec; 23(12):. PubMed ID: 30544723
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Overexpression of TIMP-1 and Sensitivity to Topoisomerase Inhibitors in Glioblastoma cell Lines.
    Aaberg-Jessen C; Fogh L; Sørensen MD; Halle B; Brünner N; Kristensen BW
    Pathol Oncol Res; 2019 Jan; 25(1):59-69. PubMed ID: 28963609
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. [Abnormality of top2a expression and its gene copy number variations in neuroblastic tumors].
    Chen JM; Zhou CJ; Ma XL; Guan DD; Yang LY; Yue P; Gong LP
    Zhonghua Bing Li Xue Za Zhi; 2016 Nov; 45(11):748-754. PubMed ID: 27821228
    [No Abstract]    [Full Text] [Related]  

  • 18. Protein expression of BIRC5, TK1, and top2a in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection.
    Kolberg M; Høland M; Lind GE; Ågesen TH; Skotheim RI; Hall KS; Mandahl N; Smeland S; Mertens F; Davidson B; Lothe RA
    Mol Oncol; 2015 Jun; 9(6):1129-39. PubMed ID: 25769404
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a top2a inhibitor.
    Arivazhagan A; Kumar DM; Sagar V; Patric IR; Sridevi S; Thota B; Srividya MR; Prasanna K; Thennarasu K; Mondal N; Hegde AS; Chandramouli BA; Santosh V; Rao MR; Kondaiah P; Somasundaram K
    J Neurooncol; 2012 Apr; 107(2):289-97. PubMed ID: 22102081
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Ependymoma gene expression profiles associated with histological subtype, proliferation, and patient survival.
    Lukashova-v Zangen I; Kneitz S; Monoranu CM; Rutkowski S; Hinkes B; Vince GH; Huang B; Roggendorf W
    Acta Neuropathol; 2007 Mar; 113(3):325-37. PubMed ID: 17265049
    [TBL] [Abstract] [Full Text] [Related]  


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