BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND TOP2A, TOP2, TP2A AND Treatment
23 results:

  • 1. The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma.
    Shirai Y; Ueno T; Kojima S; Ikeuchi H; Kitada R; Koyama T; Takahashi F; Takahashi K; Ichimura K; Yoshida A; Sugino H; Mano H; Narita Y; Takahashi M; Kohsaka S
    J Neurooncol; 2024 Mar; 167(1):75-88. PubMed ID: 38363490
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Knockdown of NUSAP1 inhibits cell proliferation and invasion through downregulation of top2a in human glioblastoma.
    Hu Y; Xue Z; Qiu C; Feng Z; Qi Q; Wang J; Jin W; Zhong Z; Liu X; Li W; Zhang Q; Huang B; Chen A; Wang J; Yang N; Zhou W
    Cell Cycle; 2022 Sep; 21(17):1842-1855. PubMed ID: 35532155
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. PTEN loss drives resistance to the neddylation inhibitor MLN4924 in glioblastoma and can be overcome with top2a inhibitors.
    Ferdosi SR; Taylor B; Lee M; Tang N; Peng S; Bybee R; Reid G; Hartman L; Garcia-Mansfield K; Sharma R; Pirrotte P; Ma J; Parisian AD; Furnari F; Dhruv HD; Berens ME
    Neuro Oncol; 2022 Nov; 24(11):1857-1868. PubMed ID: 35305088
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Multivariate analysis reveals differentially expressed genes among distinct subtypes of diffuse astrocytic gliomas: diagnostic implications.
    González-García N; Nieto-Librero AB; Vital AL; Tao HJ; González-Tablas M; Otero Á; Galindo-Villardón P; Orfao A; Tabernero MD
    Sci Rep; 2020 Jul; 10(1):11270. PubMed ID: 32647207
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Ribosomal protein S11 influences glioma response to top2 poisons.
    Awah CU; Chen L; Bansal M; Mahajan A; Winter J; Lad M; Warnke L; Gonzalez-Buendia E; Park C; Zhang D; Feldstein E; Yu D; Zannikou M; Balyasnikova IV; Martuscello R; Konerman S; Győrffy B; Burdett KB; Scholtens DM; Stupp R; Ahmed A; Hsu P; Sonabend AM
    Oncogene; 2020 Jul; 39(27):5068-5081. PubMed ID: 32528131
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Screening and identification of key biomarkers for retinoblastoma: Evidence from bioinformatics analysis.
    Huang J; Zhang L; Li Z; Lu X
    Medicine (Baltimore); 2020 May; 99(20):e19952. PubMed ID: 32443297
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Screening for genes and subnetworks associated with atypical teratoid/rhabdoid tumors using bioinformatics analysis.
    Li G; Wang Y; Cai L; Zhou L
    Int J Neurosci; 2021 Apr; 131(4):319-326. PubMed ID: 32202192
    [No Abstract]    [Full Text] [Related]  

  • 8. Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine tumors.
    Scott AT; Weitz M; Breheny PJ; Ear PH; Darbro B; Brown BJ; Braun TA; Li G; Umesalma S; Kaemmer CA; Maharjan CK; Quelle DE; Bellizzi AM; Chandrasekharan C; Dillon JS; O'Dorisio TM; Howe JR
    Clin Cancer Res; 2020 Apr; 26(8):2011-2021. PubMed ID: 31937620
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Inhibition of DNA-PK potentiates the synergistic effect of NK314 and etoposide combination on human glioblastoma cells.
    Kopa P; Macieja A; Gulbas I; Pastwa E; Poplawski T
    Mol Biol Rep; 2020 Jan; 47(1):67-76. PubMed ID: 31583565
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Identification of potential core genes and miRNAs in testicular seminoma via bioinformatics analysis.
    Wang K; Chen Y; Zhao Z; Feng M; Zhang S
    Mol Med Rep; 2019 Nov; 20(5):4013-4022. PubMed ID: 31545448
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Identification of Potential Biomarkers in Glioblastoma through Bioinformatic Analysis and Evaluating Their Prognostic Value.
    Zhou Y; Yang L; Zhang X; Chen R; Chen X; Tang W; Zhang M
    Biomed Res Int; 2019; 2019():6581576. PubMed ID: 31119182
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Identification of Driver Genes and Key Pathways of Ependymoma.
    Zhong S; Yan Q; Ge J; Dou G; Xu H; Zhao G
    Turk Neurosurg; 2024; 34(2):184-195. PubMed ID: 30649797
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. 3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
    Li W; Liu J; Fu W; Zheng X; Ren L; Liu S; Wang J; Ji T; Du G
    J Exp Clin Cancer Res; 2018 Jul; 37(1):132. PubMed ID: 29970196
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Rethinking medulloblastoma from a targeted therapeutics perspective.
    Hashimoto Y; Penas-Prado M; Zhou S; Wei J; Khatua S; Hodges TR; Sanai N; Xiu J; Gatalica Z; Kim L; Kesari S; Rao G; Spetzler D; Heimberger A
    J Neurooncol; 2018 Sep; 139(3):713-720. PubMed ID: 29869738
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Overexpression of TIMP-1 and Sensitivity to Topoisomerase Inhibitors in Glioblastoma cell Lines.
    Aaberg-Jessen C; Fogh L; Sørensen MD; Halle B; Brünner N; Kristensen BW
    Pathol Oncol Res; 2019 Jan; 25(1):59-69. PubMed ID: 28963609
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Quantitative Proteomic Profiling of Tachyplesin I Targets in U251 Gliomaspheres.
    Li X; Dai J; Tang Y; Li L; Jin G
    Mar Drugs; 2017 Jan; 15(1):. PubMed ID: 28106765
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Clinical analysis of spinal stereotactic radiosurgery in the treatment of neurogenic tumors.
    Shin DW; Sohn MJ; Kim HS; Lee DJ; Jeon SR; Hwang YJ; Jho EH
    J Neurosurg Spine; 2015 Oct; 23(4):429-37. PubMed ID: 26140405
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Protein expression of BIRC5, TK1, and top2a in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection.
    Kolberg M; Høland M; Lind GE; Ågesen TH; Skotheim RI; Hall KS; Mandahl N; Smeland S; Mertens F; Davidson B; Lothe RA
    Mol Oncol; 2015 Jun; 9(6):1129-39. PubMed ID: 25769404
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma.
    Sonabend AM; Carminucci AS; Amendolara B; Bansal M; Leung R; Lei L; Realubit R; Li H; Karan C; Yun J; Showers C; Rothcock R; O J; Califano A; Canoll P; Bruce JN
    Neuro Oncol; 2014 Sep; 16(9):1210-9. PubMed ID: 24637229
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The microarray gene profiling analysis of glioblastoma cancer cells reveals genes affected by FAK inhibitor Y15 and combination of Y15 and temozolomide.
    Huang G; Ho B; Conroy J; Liu S; Qiang H; Golubovskaya V
    Anticancer Agents Med Chem; 2014 Jan; 14(1):9-17. PubMed ID: 23387973
    [TBL] [Abstract] [Full Text] [Related]  


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