BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND TP53, TRP53, 7157, ENSG00000141510, P04637, LFS1, P53 AND Clinical Outcome
128 results:

  • 1. Presumed Pathogenic germ Line and Somatic Variants in African American Thyroid Cancer.
    Hurst ZA; Liyanarachchi S; Brock P; He H; Nabhan F; Veloski C; Toland AE; Ringel MD; Jhiang SM
    Thyroid; 2024 Mar; 34(3):378-387. PubMed ID: 38062767
    [No Abstract]    [Full Text] [Related]  

  • 2. Whole-exome sequencing reveals mutational profiles of anorectal and gynecological melanoma.
    Sun W; Liu K; Zhou H; Zhao F; Dong Y; Xu Y; Kong Y; Wang M; Cheng X; Chen Y
    Med Oncol; 2023 Oct; 40(11):330. PubMed ID: 37831226
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.
    Kolodziejczak AS; Guerrini-Rousseau L; Planchon JM; Ecker J; Selt F; Mynarek M; Obrecht D; Sill M; Autry RJ; Stutheit-Zhao E; Hirsch S; Amouyal E; Dufour C; Ayrault O; Torrejon J; Waszak SM; Ramaswamy V; Pentikainen V; Demir HA; Clifford SC; Schwalbe EC; Massimi L; Snuderl M; Galbraith K; Karajannis MA; Hill K; Li BK; Walsh M; White CL; Redmond S; Loizos L; Jakob M; Kordes UR; Schmid I; Hauer J; Blattmann C; Filippidou M; Piccolo G; Scheurlen W; Farrag A; Grund K; Sutter C; Pietsch T; Frank S; Schewe DM; Malkin D; Ben-Arush M; Sehested A; Wong TT; Wu KS; Liu YL; Carceller F; Mueller S; Stoller S; Taylor MD; Tabori U; Bouffet E; Kool M; Sahm F; von Deimling A; Korshunov A; von Hoff K; Kratz CP; Sturm D; Jones DTW; Rutkowski S; van Tilburg CM; Witt O; Bougeard G; Pajtler KW; Pfister SM; Bourdeaut F; Milde T
    Neuro Oncol; 2023 Dec; 25(12):2273-2286. PubMed ID: 37379234
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. lncRNA TRHDE-AS1 Correlated with Genomic Landscape and clinical outcome in Glioma.
    Xie J; Lin Y; Li Y; Fang A; Li X; Wang S; Li W
    Genes (Basel); 2023 May; 14(5):. PubMed ID: 37239411
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker outcomes from PNOC003.
    Kline C; Jain P; Kilburn L; Bonner ER; Gupta N; Crawford JR; Banerjee A; Packer RJ; Villanueva-Meyer J; Luks T; Zhang Y; Kambhampati M; Zhang J; Yadavilli S; Zhang B; Gaonkar KS; Rokita JL; Kraya A; Kuhn J; Liang W; Byron S; Berens M; Molinaro A; Prados M; Resnick A; Waszak SM; Nazarian J; Mueller S
    Clin Cancer Res; 2022 Sep; 28(18):3965-3978. PubMed ID: 35852795
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Primary mediastinal germ cell tumor and clonally related and unique hematologic neoplasms with i(12p) and tp53 mutation: A report of two cases.
    Fang H; Toruner GA; Tang Z; Tang G; Weissferdt A; Tashakori M; El Hussein S; Thakral B; Quesada AE; Wang W; Patel KP; Garcia-Manero G; Medeiros LJ; Bueso-Ramos CE; Jelloul FZ
    Ann Diagn Pathol; 2022 Aug; 59():151951. PubMed ID: 35489185
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Chromosome 3p25.3 Gain Is Associated With Cisplatin Resistance and Is an Independent Predictor of Poor outcome in Male Malignant germ cell tumors.
    Timmerman DM; Eleveld TF; Sriram S; Dorssers LCJ; Gillis AJM; Schmidtova S; Kalavska K; van de Werken HJG; Oing C; Honecker F; Mego M; Looijenga LHJ
    J Clin Oncol; 2022 Sep; 40(26):3077-3087. PubMed ID: 35442716
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Can a signature molecular-profile define disparate survival in BRAF-positive Gliosarcoma and identify novel targets for therapeutic intervention?
    Gandhi P; Khare R; Garg N; Mishra J
    J Cancer Res Ther; 2022; 18(1):224-230. PubMed ID: 35381788
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent tp53 mutations and recurrent monosomy 13.
    Pratt D; Abdullaev Z; Papanicolau-Sengos A; Ketchum C; Panneer Selvam P; Chung HJ; Lee I; Raffeld M; Gilbert MR; Armstrong TS; Pytel P; Borys E; Klonoski JM; McCord M; Horbinski C; Brat D; Perry A; Solomon D; Eberhart C; Giannini C; Quezado M; Aldape K
    Acta Neuropathol; 2022 Mar; 143(3):403-414. PubMed ID: 35103816
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
    Suwala AK; Stichel D; Schrimpf D; Kloor M; Wefers AK; Reinhardt A; Maas SLN; Kratz CP; Schweizer L; Hasselblatt M; Snuderl M; Abedalthagafi MSJ; Abdullaev Z; Monoranu CM; Bergmann M; Pekrun A; Freyschlag C; Aronica E; Kramm CM; Hinz F; Sievers P; Korshunov A; Kool M; Pfister SM; Sturm D; Jones DTW; Wick W; Unterberg A; Hartmann C; Dodgshun A; Tabori U; Wesseling P; Sahm F; von Deimling A; Reuss DE
    Acta Neuropathol; 2021 Jan; 141(1):85-100. PubMed ID: 33216206
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. p53 and MDM2 expression in primary and metastatic testicular germ cell tumors: Association with clinical outcome.
    Lobo J; Alzamora MA; Guimarães R; Cantante M; Lopes P; Braga I; Maurício J; Jerónimo C; Henrique R
    Andrology; 2020 Sep; 8(5):1233-1242. PubMed ID: 32384200
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Expression of GNAS, tp53, and PTEN Improves the Patient Prognostication in Sonic Hedgehog (SHH) Medulloblastoma Subgroup.
    da Silva LS; Mançano BM; de Paula FE; Dos Reis MB; de Almeida GC; Matsushita M; Junior CA; Evangelista AF; Saggioro F; Serafini LN; Stavale JN; Malheiros SMF; Lima M; Hajj GNM; de Lima MA; Taylor MD; Leal LF; Reis RM
    J Mol Diagn; 2020 Jul; 22(7):957-966. PubMed ID: 32380172
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Ki-67 Index of 55% Distinguishes Two Groups of Bronchopulmonary Pure and Composite Large cell Neuroendocrine Carcinomas with Distinct Prognosis.
    Milione M; Maisonneuve P; Grillo F; Mangogna A; Centonze G; Prinzi N; Pusceddu S; Garzone G; Cattaneo L; Busico A; Bossi P; Spaggiari P; Pellegrinelli A; Del Gobbo A; Ferrero S; Kankava K; Pruneri G; Rolli L; Roca E; Bercich L; Tironi A; Benvenuti MR; Gallazzi MS; Romano R; Berruti A; Pastorino U; Capella C
    Neuroendocrinology; 2021; 111(5):475-489. PubMed ID: 32365350
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Genomic analysis of primary and recurrent gliomas reveals clinical outcome related molecular features.
    Zhang L; Liu Z; Li J; Huang T; Wang Y; Chang L; Zheng W; Ma Y; Chen F; Gong X; Yuan Q; Teaw S; Fang X; Song T; Huo L; Li X; Xia X; Liu Z; Wu J
    Sci Rep; 2019 Nov; 9(1):16058. PubMed ID: 31690770
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. A germline variant of tp53 in paediatric diffuse leptomeningeal glioneuronal tumour.
    Tan GIL; Merchant K; Tan EEK; Low DCY; Ng LP; Seow WT; Low SYY
    Childs Nerv Syst; 2019 Jun; 35(6):1021-1027. PubMed ID: 30937530
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Medulloblastoma, WNT-activated/SHH-activated: clinical impact of molecular analysis and histogenetic evaluation.
    Cambruzzi E
    Childs Nerv Syst; 2018 May; 34(5):809-815. PubMed ID: 29582169
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. p53 expression and subcellular survivin localization improve the diagnosis and prognosis of patients with diffuse astrocytic tumors.
    Faccion RS; Bernardo PS; de Lopes GPF; Bastos LS; Teixeira CL; de Oliveira JA; Fernandes PV; Dubois LG; Chimelli L; Maia RC
    Cell Oncol (Dordr); 2018 Apr; 41(2):141-157. PubMed ID: 29374392
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Expression of p53 protein in high-grade gastroenteropancreatic neuroendocrine carcinoma.
    Ali AS; Grönberg M; Federspiel B; Scoazec JY; Hjortland GO; Grønbæk H; Ladekarl M; Langer SW; Welin S; Vestermark LW; Arola J; Österlund P; Knigge U; Sorbye H; Grimelius L; Janson ET
    PLoS One; 2017; 12(11):e0187667. PubMed ID: 29112960
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. HDAC4 and HDAC6 sustain DNA double strand break repair and stem-like phenotype by promoting radioresistance in glioblastoma cells.
    Marampon F; Megiorni F; Camero S; Crescioli C; McDowell HP; Sferra R; Vetuschi A; Pompili S; Ventura L; De Felice F; Tombolini V; Dominici C; Maggio R; Festuccia C; Gravina GL
    Cancer Lett; 2017 Jul; 397():1-11. PubMed ID: 28342984
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The anti-neoplastic activity of Vandetanib against high-risk medulloblastoma variants is profoundly enhanced by additional PI3K inhibition.
    Craveiro RB; Ehrhardt M; Velz J; Olschewski M; Goetz B; Pietsch T; Dilloo D
    Oncotarget; 2017 Jul; 8(29):46915-46927. PubMed ID: 28159923
    [TBL] [Abstract] [Full Text] [Related]  


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