BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Head and neck cancer AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1
33 results:

  • 1. NUMA1 modulates apoptosis of esophageal squamous cell carcinoma cells through regulating ASK1-JNK signaling pathway.
    Yin S; Zhao S; Li J; Liu K; Ma X; Zhang Z; Wang R; Tian J; Liu F; Song Y; Song M; Zhao R; Yang R; Lee MH; Dong Z
    Cell Mol Life Sci; 2023 Jul; 80(8):211. PubMed ID: 37462735
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. TERT promoter mutations in head and neck squamous cell carcinoma: A systematic review and meta-analysis on prevalence and prognostic significance.
    Boscolo-Rizzo P; Tirelli G; Polesel J; Sia E; Phillips V; Borsetto D; De Rossi A; Giunco S
    Oral Oncol; 2023 May; 140():106398. PubMed ID: 37075587
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Driving role of head and neck cancer cell secretome on the invasion of stromal fibroblasts: Mechanistic insights by phosphoproteomics.
    Prieto-Fernandez L; Villaronga MLA; Hermida-Prado F; Hijazi M; Montoro-Jimenez I; Pevida M; Llames S; Rodrigo JP; Cutillas P; Calvo F; Garcia-Pedrero JM; Alvarez-Teijeiro S
    Biomed Pharmacother; 2023 Feb; 158():114176. PubMed ID: 36916400
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Hsa_circ_0081069 facilitates tongue squamous cell carcinoma progression by modulating map2k4 expression via miR-634.
    Pan C; Su Z; Xie H; Ning Y; Li S; Xiao H
    Odontology; 2023 Apr; 111(2):474-486. PubMed ID: 36181561
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Combined high energy of extracorporeal shock wave and 5-FU effectively suppressed the proliferation and growth of tongue squamous cell carcinoma.
    Chang CL; Chen KH; Sung PH; Chiang JY; Huang CR; Chen HH; Yip HK
    Biomed Pharmacother; 2021 Oct; 142():112036. PubMed ID: 34411913
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Single nucleotide polymorphisms within NFKBIA are associated with nasopharyngeal carcinoma susceptibility in Chinese Han population.
    Zhang H; Deng S; Zhang J; Zhu G; Zhou J; Ye W; Wang Q; Wang Y; Zou B; Zhang P; Zhang S; Lang J; Lu S
    Cytokine; 2021 Feb; 138():155356. PubMed ID: 33160813
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. microRNA-124-3p inhibits tumourigenesis by targeting mitogen-activated protein kinase 4 in papillary thyroid carcinoma.
    Sun Y; Zhang L; Zhang S
    Cell Biochem Funct; 2020 Dec; 38(8):1017-1024. PubMed ID: 32495394
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating map2k4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
    Liu Y; Jiang Q; Liu X; Lin X; Tang Z; Liu C; Zhou J; Zhao M; Li X; Cheng Z; Li L; Xie Y; Liu Z; Fang W
    EBioMedicine; 2019 Oct; 48():386-404. PubMed ID: 31594754
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Protein kinase p38α signaling in dendritic cells regulates colon inflammation and tumorigenesis.
    Zheng T; Zhang B; Chen C; Ma J; Meng D; Huang J; Hu R; Liu X; Otsu K; Liu AC; Li H; Yin Z; Huang G
    Proc Natl Acad Sci U S A; 2018 Dec; 115(52):E12313-E12322. PubMed ID: 30541887
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. mkk4 activates non-canonical NFκB signaling by promoting NFκB2-p100 processing.
    Kim JS; Kim EJ; Kim HS; Kurie JM; Ahn YH
    Biochem Biophys Res Commun; 2017 Sep; 491(2):337-342. PubMed ID: 28733031
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. MicroRNA-802 plays a tumour suppressive role in tongue squamous cell carcinoma through directly targeting map2k4.
    Wu X; Gong Z; Sun L; Ma L; Wang Q
    Cell Prolif; 2017 Jun; 50(3):. PubMed ID: 28319306
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Porphyromonas gingivalis activates NFκB and MAPK pathways in human oral epithelial cells.
    Groeger S; Jarzina F; Domann E; Meyle J
    BMC Immunol; 2017 Jan; 18(1):1. PubMed ID: 28056810
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Increased acute mortality with chemoradiotherapy for locally advanced head and neck cancer in patients ≥70years.
    Strom TJ; Naghavi AO; Trotti AM; Russell J; Kish JA; McCaffrey J; Otto KJ; Harrison LB; Caudell JJ
    J Geriatr Oncol; 2017 Jan; 8(1):50-55. PubMed ID: 27720129
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. [Association between mkk4 promoter-1304T/G polymorphism and genetic susceptibility in sporadic nasopharyngeal carcinoma].
    Lu M; Kong Q; Xu X; Lu H; Lu Z; Shi K; Xu B; Guo R
    Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2016 Feb; 30(4):287-90. PubMed ID: 27373035
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression.
    Aherne ST; Smyth P; Freeley M; Smith L; Spillane C; O'Leary J; Sheils O
    Int J Mol Med; 2016 Aug; 38(2):433-45. PubMed ID: 27353001
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Genetic variants in epidermal growth factor receptor pathway genes and risk of esophageal squamous cell carcinoma and gastric cancer in a Chinese population.
    Li WQ; Hu N; Wang Z; Yu K; Su H; Wang L; Wang C; Chanock SJ; Burdett L; Ding T; Qiao YL; Fan JH; Wang Y; Xu Y; Giffen C; Xiong X; Murphy G; Tucker MA; Dawsey SM; Freedman ND; Abnet CC; Goldstein AM; Taylor PR
    PLoS One; 2013; 8(7):e68999. PubMed ID: 23874846
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Restoring KLF5 in esophageal squamous cell cancer cells activates the JNK pathway leading to apoptosis and reduced cell survival.
    Tarapore RS; Yang Y; Katz JP
    Neoplasia; 2013 May; 15(5):472-80. PubMed ID: 23633919
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. [Protein microarray analysis on changes in protein phosphorylation in recurrent nasopharyngeal carcinoma].
    Su HF; Zhang XB; Fang M; He QC; Li WF; Wu SX
    Zhonghua Yi Xue Za Zhi; 2011 Dec; 91(45):3219-22. PubMed ID: 22333108
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. [The relationship between expression of mitogen-activated protein kinase kinase 4 and metastasis in oral squamous cell carcinoma].
    Jiang N; Wu J; Qing H; Cao Y; Yang Y
    Hua Xi Kou Qiang Yi Xue Za Zhi; 2011 Oct; 29(5):555-8. PubMed ID: 22165133
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression.
    Ahn YH; Yang Y; Gibbons DL; Creighton CJ; Yang F; Wistuba II; Lin W; Thilaganathan N; Alvarez CA; Roybal J; Goldsmith EJ; Tournier C; Kurie JM
    Mol Cell Biol; 2011 Nov; 31(21):4270-85. PubMed ID: 21896780
    [TBL] [Abstract] [Full Text] [Related]  


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