BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Head and neck cancer AND MTOR, FRAP2, FRAP1, 2475, ENSG00000198793, P42345, RAPT1, RAFT1, FRAP, FLJ44809 AND Treatment
617 results:

  • 1. Augmented ERO1α upon mtorC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11.
    Wang Z; Zong H; Liu W; Lin W; Sun A; Ding Z; Chen X; Wan X; Liu Y; Hu Z; Zhang H; Li H; Liu Y; Li D; Zhang S; Zha X
    J Exp Clin Cancer Res; 2024 Apr; 43(1):112. PubMed ID: 38610018
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. PQR309, a dual PI3K/mtor inhibitor, synergizes with gemcitabine by impairing the GSK-3β and STAT3/HSP60 signaling pathways to treat nasopharyngeal carcinoma.
    Cao J; Zeng K; Chen Q; Yang T; Lu F; Lin C; Zhan J; Ma W; Zhou T; Huang Y; Luo F; Zhao H
    Cell Death Dis; 2024 Mar; 15(3):237. PubMed ID: 38555280
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Metformin in Esophageal Carcinoma: Exploring Molecular Mechanisms and Therapeutic Insights.
    Papadakos SP; Argyrou A; Lekakis V; Arvanitakis K; Kalisperati P; Stergiou IE; Konstantinidis I; Schizas D; Koufakis T; Germanidis G; Theocharis S
    Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474224
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. PHA-665752's Antigrowth and Proapoptotic Effects on HSC-3 Human Oral cancer Cells.
    Yadav AK; Wang S; Shin YM; Jang BC
    Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474118
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Differential modulation of PI3K/Akt/mtor activity by EGFR inhibitors: A rationale for co-targeting EGFR and PI3K in cisplatin-resistant HNSCC.
    Liao J; Yang Z; Azarbarzin S; Cullen KJ; Dan H
    Head Neck; 2024 May; 46(5):1126-1135. PubMed ID: 38429897
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Different Impacts of DNA-PK and mtor Kinase Inhibitors in Combination with Ionizing Radiation on HNSCC and Normal Tissue Cells.
    Klieber N; Hildebrand LS; Faulhaber E; Symank J; Häck N; Härtl A; Fietkau R; Distel LV
    Cells; 2024 Feb; 13(4):. PubMed ID: 38391917
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Imaging as an early biomarker to predict sensitivity to everolimus for progressive NF2-related vestibular schwannoma.
    Nghiemphu PL; Vitte J; Dombi E; Nguyen T; Wagle N; Ishiyama A; Sepahdari AR; Cachia D; Widemann BC; Brackmann DE; Doherty JK; Kalamarides M; Giovannini M
    J Neurooncol; 2024 Apr; 167(2):339-348. PubMed ID: 38372904
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Artesunate-loaded solid lipid nanoparticles resist esophageal squamous cell carcinoma by inducing Ferroptosis through inhibiting the AKT/mtor signaling.
    Xia Y; Tang Y; Huang Z; Ke N; Zheng Y; Zhuang W; Zhang Y; Yin X; Tu M; Chen J; Wang Y; Huang Y
    Cell Signal; 2024 May; 117():111108. PubMed ID: 38369266
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Deep response to a combination of mtor inhibitor temsirolimus and dual immunotherapy of nivolumab/ipilimumab in poorly differentiated thyroid carcinoma with
    Oh Y; Park JH; Djunadi TA; Shah Z; Chung LI; Chae YK
    Front Endocrinol (Lausanne); 2024; 15():1304188. PubMed ID: 38356955
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. GLP-1 receptor agonist liraglutide inhibits the proliferation and migration of thyroid cancer cells.
    Zhang X; Zhang L; Wang B; Zhang X; Gu L; Guo K; Zhang X; Zhou Z
    Cell Mol Biol (Noisy-le-grand); 2023 Dec; 69(14):221-225. PubMed ID: 38279433
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma.
    Hanna GJ; Dharanesswaran H; Giobbie-Hurder A; Harran JJ; Liao Z; Pai L; Tchekmedyian V; Ruiz ES; Waldman AH; Schmults CD; Riella LV; Lizotte P; Paweletz CP; Chandraker AK; Murakami N; Silk AW
    J Clin Oncol; 2024 Mar; 42(9):1021-1030. PubMed ID: 38252908
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Evolutionary dynamics of tipifarnib in HRAS mutated head and neck squamous cell carcinoma.
    Jagadeeshan S; Suryamohan K; Shin N; Mathukkada S; Boyko A; Melikhova D; Tsareva A; Yunusova L; Pravdivtseva E; Stupichev D; Shaposhnikov K; Peterson A; Bednyagin L; Shugaev-Mendosa E; Kessler L; Burrows F; Ho AL; Agrawal N; Pearson AT; Izumchenko E; Cole G; Elkabets M; Rosenberg AJ
    Oral Oncol; 2024 Feb; 149():106688. PubMed ID: 38219706
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Network pharmacology, molecular docking and experimental study of CEP in nasopharyngeal carcinoma.
    Yang J; Qin L; Zhou S; Li J; Tu Y; Mo M; Liu X; Huang J; Qin X; Jiao A; Wei W; Yang P
    J Ethnopharmacol; 2024 Apr; 323():117667. PubMed ID: 38159821
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Phase I Study of mtorC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mtor/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
    Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
    Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The effects of HPV oncoproteins on host communication networks: Therapeutic connotations.
    Skelin J; Luk HY; Butorac D; Boon SS; Tomaić V
    J Med Virol; 2023 Dec; 95(12):e29315. PubMed ID: 38115222
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
    Wang Y; Mang X; Li D; Wang Z; Chen Y; Cai Z; Tan F
    Redox Biol; 2024 Feb; 69():102991. PubMed ID: 38103343
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Autophagy indicators in oral squamous cell carcinoma.
    Pangarkar M; Wagh U; Pathak A
    Pathology; 2024 Feb; 56(1):59-64. PubMed ID: 37981514
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Enhancing nasopharyngeal carcinoma cell radiosensitivity by suppressing AKT/mtor via CENP-N knockdown.
    Wu LZ; Zou Y; Wang BR; Ni HF; Kong YG; Hua QQ; Chen SM
    J Transl Med; 2023 Nov; 21(1):792. PubMed ID: 37940975
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. head and neck cancer stem cell maintenance relies on mtor signaling, specifically involving the mechanistic target of rapamycin complexes 1 and 2 (mtorC1 and mtorC2).
    Almeida LO; Silva LC; Emerick C; Amorim Dos Santos J; Castilho RM; Squarize CH
    Arch Oral Biol; 2024 Jan; 157():105840. PubMed ID: 37939517
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin.
    Xin Y; Jiang Q; Liu C; Qiu J
    Aging (Albany NY); 2023 Nov; 15(21):12225-12250. PubMed ID: 37925175
    [TBL] [Abstract] [Full Text] [Related]  


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