Terms: = Head and neck cancer AND PTEN, MMAC1, 5728, MGC11227, PTEN1, MHAM, P60484, BZS, ENSG00000171862 AND Treatment
235 results:
1. Deep response to a combination of mTOR inhibitor temsirolimus and dual immunotherapy of nivolumab/ipilimumab in poorly differentiated thyroid carcinoma with
Oh Y; Park JH; Djunadi TA; Shah Z; Chung LI; Chae YK
Front Endocrinol (Lausanne); 2024; 15():1304188. PubMed ID: 38356955
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2. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
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3. head and neck cancer stem cell maintenance relies on mTOR signaling, specifically involving the mechanistic target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2).
Almeida LO; Silva LC; Emerick C; Amorim Dos Santos J; Castilho RM; Squarize CH
Arch Oral Biol; 2024 Jan; 157():105840. PubMed ID: 37939517
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4. USP10 suppresses ABCG2-induced malignant characteristics of doxorubicin-resistant thyroid cancer by inhibiting PI3K/AKT pathway.
Sun J; Xiang Q; Ding D; Yan N
J Bioenerg Biomembr; 2023 Dec; 55(6):457-466. PubMed ID: 37919637
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5. Anaplastic thyroid cancer:Improved understanding of what remains a deadly disease.
Cleere EF; Prunty S; O'Neill JP
Surgeon; 2024 Feb; 22(1):e48-e53. PubMed ID: 37866980
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6. Bergenin Inhibits Tumor Growth and Overcomes Radioresistance by Targeting Aerobic Glycolysis.
Li X; Xie L; Zhou L; Gan Y; Han S; Zhou Y; Qing X; Li W
Am J Chin Med; 2023; 51(7):1905-1925. PubMed ID: 37646142
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7. Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis.
Brown M; Leon A; Kedzierska K; Moore C; Belnoue-Davis HL; Flach S; Lydon JP; DeMayo FJ; Lewis A; Bosse T; Tomlinson I; Church DN
EMBO Mol Med; 2023 Oct; 15(10):e17094. PubMed ID: 37589076
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8. MicroRNA-199a-3p suppresses the invasion and metastasis of nasopharyngeal carcinoma through SCD1/pten/AKT signaling pathway.
Hu W; Wang Y; Zhang Q; Luo Q; Huang N; Chen R; Tang X; Li X; Luo H
Cell Signal; 2023 Oct; 110():110833. PubMed ID: 37543098
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9. p-mTOR, p-ERK and pten Expression in Tumor Biopsies and Organoids as Predictive Biomarkers for Patients with HPV Negative head and neck cancer.
de Kort WWB; de Ruiter EJ; Haakma WE; Driehuis E; Devriese LA; van Es RJJ; Willems SM
Head Neck Pathol; 2023 Sep; 17(3):697-707. PubMed ID: 37486536
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10. Detecting undetectable - epidemiology, etiology, and diagnosis of carcinoma of unknown primary - systematic review.
Ostojewska J; Wieczorek I; Pachciński O; Zdziennicki W; Burdan F
Folia Med Cracov; 2023 Apr; 63(1):19-37. PubMed ID: 37406274
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11. Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
Wu Z; Wu C; Shi J; Huang Z; Lu S; Tan Y; You R; Hai L; Huang J; Guo S; Gao Y; Jin Z; Tao X; You L; Wu J
J Ethnopharmacol; 2023 Oct; 315():116702. PubMed ID: 37257705
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12. Tumour microenvironment and aberrant signaling pathways in cisplatin resistance and strategies to overcome in oral cancer.
Biswal S; Panda M; Sahoo RK; Tripathi SK; Biswal BK
Arch Oral Biol; 2023 Jul; 151():105697. PubMed ID: 37079976
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13. Molecular profiling and target actionability for precision medicine in neuroendocrine neoplasms: real-world data.
Boilève A; Faron M; Fodil-Cherif S; Bayle A; Lamartina L; Planchard D; Tselikas L; Kanaan C; Scoazec JY; Ducreux M; Italiano A; Baudin E; Hadoux J
Eur J Cancer; 2023 Jun; 186():122-132. PubMed ID: 37062210
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14. Loss of CDKN2A/B is a Molecular Marker of High-grade Histology and is Associated with Aggressive Behavior in Acinic Cell Carcinoma.
Dogan S; Xu B; Rana S; Chen H; Ghossein RA; Berger MF; Ho AL; Katabi N
Mod Pathol; 2023 Jul; 36(7):100150. PubMed ID: 36841437
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15. Survival rate prediction of nasopharyngeal carcinoma patients based on MRI and gene expression using a deep neural network.
Zhang Q; Wu G; Yang Q; Dai G; Li T; Chen P; Li J; Huang W
Cancer Sci; 2023 Apr; 114(4):1596-1605. PubMed ID: 36541519
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16. PICT-1 regulates p53 splicing and sensitivity of medullary thyroid carcinoma cells to everolimus.
Bareli Y; Shimon I; Tobar A; Rubinfeld H
J Neuroendocrinol; 2022 Oct; 34(10):e13187. PubMed ID: 36306198
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17. An integrative approach toward identification and analysis of therapeutic targets involved in HPV pathogenesis with a focus on carcinomas.
Gupta AK; Kumar M
Cancer Biomark; 2023; 36(1):31-52. PubMed ID: 36245368
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18. Long-term treatment of cancer-prone germline pten mutant mice with low-dose rapamycin extends lifespan and delays tumour development.
Tibarewal P; Rathbone V; Constantinou G; Pearce W; Adil M; Varyova Z; Folkes L; Hampson A; Classen GAE; Alves A; Carvalho S; Scudamore CL; Vanhaesebroeck B
J Pathol; 2022 Dec; 258(4):382-394. PubMed ID: 36073856
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19. Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance.
Cheng HY; Hsieh CH; Lin PH; Chen YT; Hsu DS; Tai SK; Chu PY; Yang MH
J Immunother Cancer; 2022 Aug; 10(8):. PubMed ID: 36002186
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20. EIF4A3-induced circFIP1L1 represses miR-1253 and promotes radiosensitivity of nasopharyngeal carcinoma.
Zhou X; Yuan G; Wu Y; Yan S; Jiang Q; Tang S
Cell Mol Life Sci; 2022 Jun; 79(7):357. PubMed ID: 35680727
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