BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Head and neck cancer AND PTPN11, CFC, Q06124, 5781, ENSG00000179295, SHP2, MGC14433, SHP-2, BPTP3, PTP-1D, SH-PTP3, NS1, SH-PTP2, PTP2C
51 results:

  • 1. Tyrosine phosphatase
    Chen X; Keller SJ; Hafner P; Alrawashdeh AY; Avery TY; Norona J; Zhou J; Ruess DA
    Front Immunol; 2024; 15():1340726. PubMed ID: 38504984
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Toripalimab, a therapeutic monoclonal anti-PD-1 antibody with high binding affinity to PD-1 and enhanced potency to activate human T cells.
    Rajasekaran N; Wang X; Ravindranathan S; Chin DJ; Tseng SY; Klakamp SL; Widmann K; Kapoor VN; Vexler V; Keegan P; Yao S; LaVallee T; Khare SD
    Cancer Immunol Immunother; 2024 Feb; 73(3):60. PubMed ID: 38400933
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Rescue of NLRC5 expression restores antigen processing machinery in head and neck cancer cells lacking functional STAT1 and p53.
    Kinney BLC; Gunti S; Kansal V; Parrish CJ; Saba NF; Teng Y; Henry MK; Su FY; Kwong GA; Schmitt NC
    Cancer Immunol Immunother; 2024 Jan; 73(1):10. PubMed ID: 38231444
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Immune escape of head and neck cancer mediated by the impaired MHC-I antigen presentation pathway.
    Luo X; Qiu Y; Fitzsimonds ZR; Wang Q; Chen Q; Lei YL
    Oncogene; 2024 Feb; 43(6):388-394. PubMed ID: 38177410
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Gene mutation analysis of oral submucous fibrosis cancerization in Hainan Island.
    Li B; Chen X; Xian H; Wen Q; Wang T
    PeerJ; 2023; 11():e16392. PubMed ID: 38050610
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Protein Tyrosine Phosphatase Non-Receptor 11 (
    Richards CE; Elamin YY; Carr A; Gately K; Rafee S; Cremona M; Hanrahan E; Smyth R; Ryan D; Morgan RK; Kennedy S; Hudson L; Fay J; O'Byrne K; Hennessy BT; Toomey S
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37445722
    [No Abstract]    [Full Text] [Related]  

  • 7. The inaccuracies of gastric adenocarcinoma clinical staging and its predictive factors.
    Janczewski LM; Shah D; Wells A; Bentrem DJ; Abad JD; Chawla A
    J Surg Oncol; 2023 Jun; 127(7):1116-1124. PubMed ID: 36905333
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Long non-coding RNA FAM239A promotes tumor cell proliferation and migration by regulating tyrosine phosphatase Src homology 2 domain-containing phosphatase 2 in head and neck squamous cell carcinoma.
    Li Y; Guo Y; Liu Z; Mou Y; Fang H; Yang Y; Zhao X; Zhang H; Song X
    Arch Oral Biol; 2023 Mar; 147():105615. PubMed ID: 36630765
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Pharmacologic Inhibition of shp2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1.
    Kurupi R; Floros KV; Jacob S; Chawla AT; Cai J; Hu B; Puchalapalli M; Coon CM; Khatri R; Crowther GS; Egan RK; Murchie E; Greninger P; Dalton KM; Ghotra MS; Boikos SA; Koblinski JE; Harada H; Sun Y; Morgan IM; Basu D; Dozmorov MG; Benes CH; Faber AC
    Cancer Res Commun; 2022 Sep; 2(9):1061-1074. PubMed ID: 36506869
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Bioinformatics analysis identifies potential biomarkers involved in the metastasis of locoregionally advanced nasopharyngeal carcinoma.
    Hu R; Xu X; Mo L; Chen M; Liu Y
    Medicine (Baltimore); 2022 Sep; 101(35):e30126. PubMed ID: 36107539
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. A pan-cancer analysis confirms ptpn11's potential as a prognostic and immunological biomarker.
    Cao Y; Duan H; Su A; Xu L; Lai B
    Aging (Albany NY); 2022 Jul; 14(13):5590-5610. PubMed ID: 35802774
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Deregulation of hsa_circ_0001971/miR-186 and hsa_circ_0001874/miR-296 signaling pathways promotes the proliferation of oral squamous carcinoma cells by synergistically activating shp2/PLK1 signals.
    Jun W; Shaobo O; Xianhua Z; Siyu Z; Mingyang C; Xin F; Ying C; Lan L
    Sci Rep; 2021 Oct; 11(1):20561. PubMed ID: 34663837
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Stiffness of tongue squamous cell carcinoma measured using strain elastography correlates with the amount of collagen fibers in the tumor.
    Shibata M; Ishikawa A; Ishii J; Anzai E; Yagishita H; Izumo T; Sumino J; Katsurano M; Kim Y; Kanda H; Ushijima M; Yagihara K; Yoda T
    Oral Radiol; 2022 Apr; 38(2):278-287. PubMed ID: 34302572
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Comparison of Outcomes of Conventional Septoplasty Versus Endoscopic Septoplasty using Freer's Incision in Symptomatic Deviated Nasal Septum.
    Khadgi S; Gurung U; Pradhan B; Tripathi P
    Kathmandu Univ Med J (KUMJ); 2021 Jul-Sept.; 19(75):339-344. PubMed ID: 36254421
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. PD-1 blockade delays tumor growth by inhibiting an intrinsic shp2/Ras/MAPK signalling in thyroid cancer cells.
    Liotti F; Kumar N; Prevete N; Marotta M; Sorriento D; IeranĂ² C; Ronchi A; Marino FZ; Moretti S; Colella R; Puxeddu E; Paladino S; Kano Y; Ohh M; Scala S; Melillo RM
    J Exp Clin Cancer Res; 2021 Jan; 40(1):22. PubMed ID: 33413561
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Y772 phosphorylation of EphA2 is responsible for EphA2-dependent NPC nasopharyngeal carcinoma growth by shp2/Erk-1/2 signaling pathway.
    Xiang YP; Xiao T; Li QG; Lu SS; Zhu W; Liu YY; Qiu JY; Song ZH; Huang W; Yi H; Tang YY; Xiao ZQ
    Cell Death Dis; 2020 Aug; 11(8):709. PubMed ID: 32848131
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Comparative efficacy and safety of tyrosine kinase inhibitors for thyroid cancer: a systematic review and meta-analysis.
    Oba T; Chino T; Soma A; Shimizu T; Ono M; Ito T; Kanai T; Maeno K; Ito KI
    Endocr J; 2020 Dec; 67(12):1215-1226. PubMed ID: 32814730
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. ptpn11 Knockdown Prevents Changes in the Expression of Genes Controlling Cell Cycle, Chemotherapy Resistance, and Oncogene-Induced Senescence in Human Thyroid Cells Overexpressing BRAF V600E Oncogenic Protein.
    Putlyaeva LV; Demin DE; Uvarova AN; Zinevich LS; Prokofjeva MM; Gazizova GR; Shagimardanova EI; Schwartz AM
    Biochemistry (Mosc); 2020 Jan; 85(1):108-118. PubMed ID: 32079522
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Thyroid cancer MR molecular imaging via shp2-targeted nanoparticles.
    Hu Z; Qin J; Li T; Guo J
    Int J Nanomedicine; 2019; 14():7365-7373. PubMed ID: 31686812
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Clinicopathological and prognostic significance of shp2 and Hook1 expression in patients with thyroid carcinoma.
    Cao J; Huang YQ; Jiao-Sun ; Lan XB; Ge MH
    Hum Pathol; 2018 Nov; 81():105-112. PubMed ID: 29953894
    [TBL] [Abstract] [Full Text] [Related]  


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