BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Head and neck cancer AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS
109 results:

  • 1. Oridonin inhibited epithelial-mesenchymal transition of laryngeal carcinoma by positively regulating lkb1/AMPK signaling.
    Kou B; Shi Y; Zhou Z; Yun Y; Wu Q; Zhou J; Liu W
    Int J Med Sci; 2024; 21(4):623-632. PubMed ID: 38464825
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase 2 umbrella trial.
    Besse B; Pons-Tostivint E; Park K; Hartl S; Forde PM; Hochmair MJ; Awad MM; Thomas M; Goss G; Wheatley-Price P; Shepherd FA; Florescu M; Cheema P; Chu QSC; Kim SW; Morgensztern D; Johnson ML; Cousin S; Kim DW; Moskovitz MT; Vicente D; Aronson B; Hobson R; Ambrose HJ; Khosla S; Reddy A; Russell DL; Keddar MR; Conway JP; Barrett JC; Dean E; Kumar R; Dressman M; Jewsbury PJ; Iyer S; Barry ST; Cosaert J; Heymach JV
    Nat Med; 2024 Mar; 30(3):716-729. PubMed ID: 38351187
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Genetic predisposition to differentiated thyroid cancer in the Polish population.
    Borowczyk M; Sypniewski M; Szyda J; Braszka M; Ziemnicka K; Ruchała M; Oszywa M; Król ZJ; Dobosz P
    Pol Arch Intern Med; 2024 Mar; 134(3):. PubMed ID: 38165228
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
    Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
    Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The impact of indirect notification of a cancer diagnosis and a risk model based on it to predict the prognosis of postoperative stage T3 esophageal cancer patients.
    Cheng Y; Yu M; Yao Q; He T; Zhang R; Long Z
    Medicine (Baltimore); 2023 Nov; 102(44):e35895. PubMed ID: 37932980
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. KRAS G12C in advanced NSCLC: Prevalence, co-mutations, and testing.
    Lim TKH; Skoulidis F; Kerr KM; Ahn MJ; Kapp JR; Soares FA; Yatabe Y
    Lung Cancer; 2023 Oct; 184():107293. PubMed ID: 37683526
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Molecular markers of metastatic disease in KRAS-mutant lung adenocarcinoma.
    Boiarsky D; Lydon CA; Chambers ES; Sholl LM; Nishino M; Skoulidis F; Heymach JV; Luo J; Awad MA; Janne PA; Van Allen EM; Barbie DA; Vokes NI
    Ann Oncol; 2023 Jul; 34(7):589-604. PubMed ID: 37121400
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting lkb1-AMPK-axis.
    Chen L; Zhang W; Chen D; Yang Q; Sun S; Dai Z; Li Z; Liang X; Chen C; Jiao Y; Zhi L; Zhao L; Zhang J; Liu X; Zhao J; Li M; Wang Y; Qi Y
    Signal Transduct Target Ther; 2023 Apr; 8(1):159. PubMed ID: 37080995
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.
    Hong L; Aminu M; Li S; Lu X; Petranovic M; Saad MB; Chen P; Qin K; Varghese S; Rinsurongkawong W; Rinsurongkawong V; Spelman A; Elamin YY; Negrao MV; Skoulidis F; Gay CM; Cascone T; Gandhi SJ; Lin SH; Lee PP; Carter BW; Wu CC; Antonoff MB; Sepesi B; Lewis J; Gibbons DL; Vaporciyan AA; Le X; Jack Lee J; Roy-Chowdhuri S; Routbort MJ; Gainor JF; Heymach JV; Lou Y; Wu J; Zhang J; Vokes NI
    Nat Commun; 2023 Feb; 14(1):695. PubMed ID: 36755027
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Benchmarking Outcomes for Molecularly Characterized Synchronous Oligometastatic Non-Small-Cell Lung cancer Reveals
    De B; Farooqi AS; Mitchell KG; Ludmir EB; Lewis J; Rinsurongkawong W; Rinsurongkawong V; Lee JJ; Swisher SG; Gibbons DL; Zhang J; Le X; Elamin YY; Gomez DR; Ning MS; Lin SH; Liao Z; Chang JY; Vaporciyan AA; Heymach JV; Antonoff MB; Gandhi SJ
    JCO Precis Oncol; 2023 Jan; 7():e2200540. PubMed ID: 36716413
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Over than three-year follow-up results of thermal ablation for papillary thyroid carcinoma: A systematic review and meta-analysis.
    Xue J; Teng D; Wang H
    Front Endocrinol (Lausanne); 2022; 13():971038. PubMed ID: 36353232
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. A STING operation to expose KRAS and stk11 co-mutated lung cancers.
    Skoulidis F; Heymach JV; Cascone T
    Cancer Cell; 2022 Oct; 40(10):1073-1076. PubMed ID: 36220070
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. AXL targeting restores PD-1 blockade sensitivity of
    Li H; Liu Z; Liu L; Zhang H; Han C; Girard L; Park H; Zhang A; Dong C; Ye J; Rayford A; Peyton M; Li X; Avila K; Cao X; Hu S; Alam MM; Akbay EA; Solis LM; Behrens C; Hernandez-Ruiz S; Lu W; Wistuba I; Heymach JV; Chisamore M; Micklem D; Gabra H; Gausdal G; Lorens JB; Li B; Fu YX; Minna JD; Brekken RA
    Cell Rep Med; 2022 Mar; 3(3):100554. PubMed ID: 35492873
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Immunotherapy Mechanism of Esophageal Squamous Cell Carcinoma with the Effect of stk11/AMPK Signaling Pathway.
    Xia Y; Wang P; Ye Y; Zhang S; Sun G; Xu J; Han G
    Biomed Res Int; 2022; 2022():8636527. PubMed ID: 35463992
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Analysis of Immunological Characteristics and Genomic Alterations in HPV-Positive Oropharyngeal Squamous Cell Carcinoma Based on PD-L1 Expression.
    Xu SM; Shi CJ; Xia RH; Wang LZ; Tian Z; Ye WM; Liu L; Liu SL; Zhang CY; Hu YH; Zhou R; Han Y; Wang Y; Zhang ZY; Li J
    Front Immunol; 2021; 12():798424. PubMed ID: 35145511
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Diminished Efficacy of Programmed Death-(Ligand)1 Inhibition in stk11- and KEAP1-Mutant Lung Adenocarcinoma Is Affected by KRAS Mutation Status.
    Ricciuti B; Arbour KC; Lin JJ; Vajdi A; Vokes N; Hong L; Zhang J; Tolstorukov MY; Li YY; Spurr LF; Cherniack AD; Recondo G; Lamberti G; Wang X; Venkatraman D; Alessi JV; Vaz VR; Rizvi H; Egger J; Plodkowski AJ; Khosrowjerdi S; Digumarthy S; Park H; Vaz N; Nishino M; Sholl LM; Barbie D; Altan M; Heymach JV; Skoulidis F; Gainor JF; Hellmann MD; Awad MM
    J Thorac Oncol; 2022 Mar; 17(3):399-410. PubMed ID: 34740862
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Enhanced Vulnerability of lkb1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado.
    Galan-Cobo A; Stellrecht CM; Yilmaz E; Yang C; Qian Y; Qu X; Akhter I; Ayres ML; Fan Y; Tong P; Diao L; Ding J; Giri U; Gudikote J; Nilsson M; Wierda WG; Wang J; Skoulidis F; Minna JD; Gandhi V; Heymach JV
    Mol Cancer Res; 2022 Feb; 20(2):280-292. PubMed ID: 34654720
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. High Prevalence of DICER1 Mutations and Low Frequency of Gene Fusions in Pediatric Follicular-Patterned Tumors of the Thyroid.
    Bae JS; Jung SH; Hirokawa M; Bychkov A; Miyauchi A; Lee S; Chung YJ; Jung CK
    Endocr Pathol; 2021 Sep; 32(3):336-346. PubMed ID: 34313965
    [TBL] [Abstract] [Full Text] [Related]  

  • 19.
    Jiménez-Mora E; Gallego B; Díaz-Gago S; Lasa M; Baquero P; Chiloeches A
    Int J Mol Sci; 2021 Jun; 22(11):. PubMed ID: 34204950
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Mutation patterns in recurrent and/or metastatic oropharyngeal squamous cell carcinomas in relation to human papillomavirus status.
    Reder H; Wagner S; Wuerdemann N; Langer C; Sandmann S; Braeuninger A; Dugas M; Gattenloehner S; Wittekindt C; Klussmann JP
    Cancer Med; 2021 Feb; 10(4):1347-1356. PubMed ID: 33527763
    [TBL] [Abstract] [Full Text] [Related]  


    [Next]

    of 6.