BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Head and neck cancer AND TSC1, KIAA0243, 7248, ENSG00000165699, TSC, MGC86987, LAM, hamartin AND Treatment
50 results:

  • 1. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
    Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
    Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. A survey of patients with facial angiofibromas associated with tuberous sclerosis complex: Short-, medium- and long-term efficacy and safety of topical rapamycin.
    Sigg N; Fouquet J; Morin D; Farges D; Vrignaud S; Martin L
    Ann Dermatol Venereol; 2023 Dec; 150(4):270-273. PubMed ID: 37821253
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Advantages of Totally Stapled Collard Over Circular Stapled Technique for Cervical Esophagectomy Anastomosis.
    Wang K; Xie Q; Wei X; Gong R; Shi Q; Leng X; Han Y; Fang Q
    Ann Thorac Surg; 2024 May; 117(5):1025-1033. PubMed ID: 37573994
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A Review of Topical Sirolimus for the treatment of Facial Angiofibromas in Tuberous Sclerosis Complex.
    Dao DD; Pixley JN; Akkurt ZM; Feldman SR
    Ann Pharmacother; 2024 Apr; 58(4):428-433. PubMed ID: 37386842
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Efficacy and safety of anlotinib-based chemotherapy for locally advanced or metastatic anaplastic thyroid carcinoma.
    Zheng X; Wang J; Ye T; Tang W; Pan X; Wang S; Liu J
    Endocrine; 2023 Sep; 81(3):540-546. PubMed ID: 37219702
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A Novel Tongue Squamous Cell Carcinoma Cell Line Escapes from Immune Recognition due to Genetic Alterations in
    Zheng X; Sun Y; Li Y; Ma J; Lv Y; Hu Y; Zhou Y; Zhang J
    Cells; 2022 Dec; 12(1):. PubMed ID: 36611830
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Analysis of current data on the use of topical mTOR inhibitors in the treatment of facial angiofibromas in tuberous sclerosis complex-An update.
    Balestri R; Rizzoli L; Pedrolli A; Urru SAM; Rech G; Neri I; Girardelli CR; Magnano M
    J Eur Acad Dermatol Venereol; 2023 Mar; 37(3):474-487. PubMed ID: 36300771
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Pulmonary lymphangioleiomyomatosis and renal angiomyolipoma in a patient with systemic lupus erythematosus: A case report.
    Koh JS; Oh S; Chung C
    Medicine (Baltimore); 2022 Sep; 101(38):e30554. PubMed ID: 36197220
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. tsc22D4 promotes TGFβ1-induced activation of hepatic stellate cells.
    Sakurai M; Weber P; Wolff G; Wieder A; Szendroedi J; Herzig S; Ekim Üstünel B
    Biochem Biophys Res Commun; 2022 Aug; 618():46-53. PubMed ID: 35714570
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Afatinib induces pro-survival autophagy and increases sensitivity to apoptosis in stem-like HNSCC cells.
    Liu X; Suo H; Zhou S; Hou Z; Bu M; Liu X; Xu W
    Cell Death Dis; 2021 Jul; 12(8):728. PubMed ID: 34294686
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. CIB2 regulates mTORC1 signaling and is essential for autophagy and visual function.
    Sethna S; Scott PA; Giese APJ; Duncan T; Jian X; Riazuddin S; Randazzo PA; Redmond TM; Bernstein SL; Riazuddin S; Ahmed ZM
    Nat Commun; 2021 Jun; 12(1):3906. PubMed ID: 34162842
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Oncogenic role of MiR-130a in oral squamous cell carcinoma.
    Mallela K; Shivananda S; Gopinath KS; Kumar A
    Sci Rep; 2021 Apr; 11(1):7787. PubMed ID: 33833339
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Combined treatment of disfiguring facial angiofibromas in tuberous sclerosis complex with surgical debulking and topical sirolimus.
    Patterson JL; Iyengar S; Catasus C; Kolodney JA; Zinn Z
    Cutis; 2020 Dec; 106(6):307-308. PubMed ID: 33471874
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Inhibition of miR-133b indicates poor prognosis and promotes progression of OSCC via SOX4.
    Yang J; Wang H; Xu W; Chen Z; Yan ZY; Zhang LJ
    Eur Rev Med Pharmacol Sci; 2020 Dec; 24(24):12717-12726. PubMed ID: 33378019
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The Efficacy of Everolimus for Facial Angiofibromas in Tuberous Sclerosis Complex Patients Treated for Renal Angiomyolipoma/Subependymal Giant Cell Astrocytoma.
    Wei CC; Hsiao YP; Gau SY; Wu YT; Wu CT; Wu MH; Tsai JD
    Dermatology; 2021; 237(3):444-449. PubMed ID: 33032292
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Enforced C-Src Activation Causes Compartmental Dysregulation of PI3K and PTEN Molecules in Lipid Rafts of Tongue Squamous Carcinoma Cells by Attenuating Rac1-Akt-GLUT-1-Mediated Sphingolipid Synthesis.
    Wu CW; Wang SG; Lee CH; Chan WL; Lin ML; Chen SS
    Int J Mol Sci; 2020 Aug; 21(16):. PubMed ID: 32823607
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Improved health-related quality of life in patients treated with topical sirolimus for facial angiofibroma associated with tuberous sclerosis complex.
    Hatano T; Ohno Y; Imai Y; Moritake J; Endo K; Tamari M; Egawa S
    Orphanet J Rare Dis; 2020 Jun; 15(1):133. PubMed ID: 32487130
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Natural history of a fibrous cephalic plaque and sustained eight decade follow-up in an 80 year old with tuberous sclerosis complex type 2.
    Kirk CW; Donnelly DE; Hardy R; Shepherd CW; Morrison PJ
    Ulster Med J; 2020 Jan; 89(1):14-16. PubMed ID: 32218621
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The efficacy and safety of topical rapamycin-calcitriol for facial angiofibromas in patients with tuberous sclerosis complex: a prospective, double-blind, randomized clinical trial.
    Chen PL; Hong JB; Shen LJ; Chen YT; Wang SJ; Liao YH
    Br J Dermatol; 2020 Oct; 183(4):655-663. PubMed ID: 32064596
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Comparative Effects of Topical 0.2% Sirolimus for Angiofibromas in Adults and Pediatric Patients with Tuberous Sclerosis Complex.
    Lee YI; Lee JH; Kim DY; Chung KY; Shin JU
    Dermatology; 2018; 234(1-2):13-22. PubMed ID: 29925060
    [TBL] [Abstract] [Full Text] [Related]  


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