BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Kidney tumors AND CDKN2A, CDK4I, 1029, ENSG00000147889, P42771, p14, CMM2, ARF, TP16, p16, MTS1, p19, p16INK4a, INK4a, CDKN2, p16INK4, p14ARF, MLM, INK4 AND Treatment
73 results:

  • 1. Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial.
    Machiels JP; Tao Y; Licitra L; Burtness B; Tahara M; Rischin D; Alves G; Lima IPF; Hughes BGM; Pointreau Y; Aksoy S; Laban S; Greil R; Burian M; Hetnał M; Delord JP; Mesía R; Taberna M; Waldron JN; Simon C; Grégoire V; Harrington KJ; Swaby RF; Zhang Y; Gumuscu B; Bidadi B; Siu LL;
    Lancet Oncol; 2024 May; 25(5):572-587. PubMed ID: 38561010
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. [Cytopathological characteristics of SMARCA4-deficient thoracic undifferentiated tumors in serous effusion].
    Wang WN; Liu XT; Liang YM
    Zhonghua Bing Li Xue Za Zhi; 2024 Feb; 53(2):143-148. PubMed ID: 38281781
    [No Abstract]    [Full Text] [Related]  

  • 3. The chemotherapeutic agent doxorubicin induces brain senescence, with modulation by APOE genotype.
    Demby T; Gross PS; Mandelblatt J; Huang JK; Rebeck GW
    Exp Neurol; 2024 Jan; 371():114609. PubMed ID: 37944881
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Identification and verification of a novel anoikis-related gene signature with prognostic significance in clear cell renal cell carcinoma.
    He Z; Gu Y; Yang H; Fu Q; Zhao M; Xie Y; Liu Y; Du W
    J Cancer Res Clin Oncol; 2023 Oct; 149(13):11661-11678. PubMed ID: 37402968
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Comprehensive analyses of cuproptosis-related gene cdkn2a on prognosis and immunologic therapy in human tumors.
    Zhang D; Wang T; Zhou Y; Zhang X
    Medicine (Baltimore); 2023 Apr; 102(14):e33468. PubMed ID: 37026918
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Spatiotemporal evolution of the clear cell renal cell carcinoma microenvironment links intra-tumoral heterogeneity to immune escape.
    Golkaram M; Kuo F; Gupta S; Carlo MI; Salmans ML; Vijayaraghavan R; Tang C; Makarov V; Rappold P; Blum KA; Zhao C; Mehio R; Zhang S; Godsey J; Pawlowski T; DiNatale RG; Morris LGT; Durack J; Russo P; Kotecha RR; Coleman J; Chen YB; Reuter VE; Motzer RJ; Voss MH; Liu L; Reznik E; Chan TA; Hakimi AA
    Genome Med; 2022 Dec; 14(1):143. PubMed ID: 36536472
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma.
    Bian Z; Fan R; Xie L
    Genes (Basel); 2022 May; 13(5):. PubMed ID: 35627236
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Genomics of Clear-cell Renal Cell Carcinoma: A Systematic Review and Meta-analysis.
    Bui TO; Dao VT; Nguyen VT; Feugeas JP; Pamoukdjian F; Bousquet G
    Eur Urol; 2022 Apr; 81(4):349-361. PubMed ID: 34991918
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. [Clinicopathological analysis of lung metastatic tumor].
    Lou N; Niu YR; Yang F; Lu ZH
    Zhonghua Bing Li Xue Za Zhi; 2021 Sep; 50(9):1039-1044. PubMed ID: 34496496
    [No Abstract]    [Full Text] [Related]  

  • 10. Molecular determinants of response to PD-L1 blockade across tumor types.
    Banchereau R; Leng N; Zill O; Sokol E; Liu G; Pavlick D; Maund S; Liu LF; Kadel E; Baldwin N; Jhunjhunwala S; Nickles D; Assaf ZJ; Bower D; Patil N; McCleland M; Shames D; Molinero L; Huseni M; Sanjabi S; Cummings C; Mellman I; Mariathasan S; Hegde P; Powles T
    Nat Commun; 2021 Jun; 12(1):3969. PubMed ID: 34172722
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Purification of a novel protein with cytotoxicity against non-small-cell lung cancer cells from Boletus bicolor.
    Zhang MH; Zhou R; Liu F; Ng TB
    Arch Pharm (Weinheim); 2021 Sep; 354(9):e2100135. PubMed ID: 34076300
    [TBL] [Abstract] [Full Text] [Related]  

  • 12.
    Adib E; Nassar AH; Akl EW; Abou Alaiwi S; Nuzzo PV; Mouhieddine TH; Sonpavde G; Haddad RI; Mouw KW; Giannakis M; Hodi FS; Shukla SA; Gusev A; Braun DA; Choueiri TK; Kwiatkowski DJ
    Clin Cancer Res; 2021 Jul; 27(14):4025-4035. PubMed ID: 34074656
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Mutant cdkn2a regulates p16/p14 expression by alternative splicing in renal cell carcinoma metastasis.
    Sun Q; Chen S; Hou Y; Wen X; Teng X; Zhang H; Lai C; Lai M
    Pathol Res Pract; 2021 Jul; 223():153453. PubMed ID: 34022680
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Characterization of genetically defined sporadic and hereditary type 1 papillary renal cell carcinoma cell lines.
    Yang Y; Ricketts CJ; Vocke CD; Killian JK; Padilla-Nash HM; Lang M; Wei D; Lee YH; Wangsa D; Sourbier C; Meltzer PS; Ried T; Merino MJ; Metwalli AR; Ball MW; Srinivasan R; Linehan WM
    Genes Chromosomes Cancer; 2021 Jun; 60(6):434-446. PubMed ID: 33527590
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Site-Specific and Targeted Therapy Based on Molecular Profiling by Next-Generation Sequencing for Cancer of Unknown Primary Site: A Nonrandomized Phase 2 Clinical Trial.
    Hayashi H; Takiguchi Y; Minami H; Akiyoshi K; Segawa Y; Ueda H; Iwamoto Y; Kondoh C; Matsumoto K; Takahashi S; Yasui H; Sawa T; Onozawa Y; Chiba Y; Togashi Y; Fujita Y; Sakai K; Tomida S; Nishio K; Nakagawa K
    JAMA Oncol; 2020 Dec; 6(12):1931-1938. PubMed ID: 33057591
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Adverse histology, homozygous loss of cdkn2a/B, and complex genomic alterations in locally advanced/metastatic renal mucinous tubular and spindle cell carcinoma.
    Yang C; Cimera RS; Aryeequaye R; Jayakumaran G; Sarungbam J; Al-Ahmadie HA; Gopalan A; Sirintrapun SJ; Fine SW; Tickoo SK; Epstein JI; Reuter VE; Zhang Y; Chen YB
    Mod Pathol; 2021 Feb; 34(2):445-456. PubMed ID: 32879414
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Comprehensive Genomic Profiling of Adult Renal Sarcomas Provides Insight into Disease Biology and Opportunities for Targeted Therapies.
    Yakirevich E; Madison R; Fridman E; Mangray S; Carneiro BA; Lu S; Cooke M; Bratslavsky G; Webster J; Ross JS; Ali SM
    Eur Urol Oncol; 2021 Apr; 4(2):282-288. PubMed ID: 31412008
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications.
    Linehan WM; Ricketts CJ
    Nat Rev Urol; 2019 Sep; 16(9):539-552. PubMed ID: 31278395
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Cabozantinib in advanced non-clear-cell renal cell carcinoma: a multicentre, retrospective, cohort study.
    Martínez Chanzá N; Xie W; Asim Bilen M; Dzimitrowicz H; Burkart J; Geynisman DM; Balakrishnan A; Bowman IA; Jain R; Stadler W; Zakharia Y; Narayan V; Beuselinck B; McKay RR; Tripathi A; Pachynski R; Hahn AW; Hsu J; Shah SA; Lam ET; Rose TL; Mega AE; Vogelzang N; Harrison MR; Mortazavi A; Plimack ER; Vaishampayan U; Hammers H; George S; Haas N; Agarwal N; Pal SK; Srinivas S; Carneiro BA; Heng DYC; Bosse D; Choueiri TK; Harshman LC
    Lancet Oncol; 2019 Apr; 20(4):581-590. PubMed ID: 30827746
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Non-α-fetoprotein-producing adrenal hepatoid adenocarcinoma: A case report and literature review.
    Lin J; Cao Y; Yu L; Lin L
    Medicine (Baltimore); 2018 Sep; 97(39):e12336. PubMed ID: 30278510
    [TBL] [Abstract] [Full Text] [Related]  


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