BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Kidney tumors AND CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1
15 results:

  • 1. Pharmacokinetics of gefitinib in elderly patients with EGFR-mutated advanced non-small cell lung cancer: a prospective study.
    Nio Y; Ishida H; Matsumoto N; Kusumoto S; Kubota Y; Tsunoda T; Sasaki Y; Fujita KI
    BMC Pulm Med; 2022 Nov; 22(1):454. PubMed ID: 36451169
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Preclinical pharmacokinetics, CYP phenotyping, and tissue distribution study of novel anti-breast cancer candidate S-011-1559.
    Verma SK; Biswas A; Kumar M; Mishra A; Choudhury AD; Agrawal S; Sanap SN; Bisen AC; Sharma AK; Panda G; Bhatta RS
    Xenobiotica; 2022 May; 52(5):476-487. PubMed ID: 35819259
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Dimethoxycurcumin reduces proliferation and induces apoptosis in renal tumor cells more efficiently than demethoxycurcumin and curcumin.
    Zanetti TA; Biazi BI; Coatti GC; Baranoski A; Marques LA; Corveloni AC; Mantovani MS
    Chem Biol Interact; 2021 Apr; 338():109410. PubMed ID: 33582110
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein).
    van Hoppe S; Jamalpoor A; Rood JJM; Wagenaar E; Sparidans RW; Beijnen JH; Schinkel AH
    Pharmacol Res; 2019 Aug; 146():104297. PubMed ID: 31175939
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Complex disease-, gene-, and drug-drug interactions: impacts of renal function, cyp2d6 phenotype, and OCT2 activity on veliparib pharmacokinetics.
    Li J; Kim S; Sha X; Wiegand R; Wu J; LoRusso P
    Clin Cancer Res; 2014 Aug; 20(15):3931-44. PubMed ID: 24947923
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Risk of renal cell carcinoma and polymorphism in phase I xenobiotic metabolizing CYP1A1 and cyp2d6 enzymes.
    Ahmad ST; Arjumand W; Seth A; Nafees S; Rashid S; Ali N; Hamiza OO; Sultana S
    Urol Oncol; 2013 Oct; 31(7):1350-7. PubMed ID: 22281432
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Pazopanib: the newest tyrosine kinase inhibitor for the treatment of advanced or metastatic renal cell carcinoma.
    Keisner SV; Shah SR
    Drugs; 2011 Mar; 71(4):443-54. PubMed ID: 21395357
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Superoxide dismutase and cytochrome P450 isoenzymes might be associated with higher risk of renal cell carcinoma in male patients.
    Sverko A; Sobočanec S; Kušić B; Mačak-Šafranko Z; Sarić A; Leniček T; Kraus O; Andrišić L; Korolija M; Balog T; Sunjić SB; Marotti M
    Int Immunopharmacol; 2011 Jun; 11(6):639-45. PubMed ID: 21238623
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib.
    Gardner ER; Burger H; van Schaik RH; van Oosterom AT; de Bruijn EA; Guetens G; Prenen H; de Jong FA; Baker SD; Bates SE; Figg WD; Verweij J; Sparreboom A; Nooter K
    Clin Pharmacol Ther; 2006 Aug; 80(2):192-201. PubMed ID: 16890580
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Cytochrome P450 gene polymorphism and cancer.
    Agundez JA
    Curr Drug Metab; 2004 Jun; 5(3):211-24. PubMed ID: 15180491
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Association of GSTT1 non-null and NAT1 slow/rapid genotypes with von Hippel-Lindau tumour suppressor gene transversions in sporadic renal cell carcinoma.
    Gallou C; Longuemaux S; Deloménie C; Méjean A; Martin N; Martinet S; Palais G; Bouvier R; Droz D; Krishnamoorthy R; Junien C; Béroud C; Dupret JM
    Pharmacogenetics; 2001 Aug; 11(6):521-35. PubMed ID: 11505222
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Detection of anti-LKM-1(anti-cyp2d6) by an enzyme-linked immunosorbent assay in adult patients with chronic liver diseases.
    Miyakawa H; Kikazawa E; Abe K; Kikuchi K; Fujikawa H; Matsushita M; Kawaguchi N; Morizane T; Ohya K; Kako M
    Autoimmunity; 1999; 30(2):107-14. PubMed ID: 10435724
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Candidate genetic modifiers of individual susceptibility to renal cell carcinoma: a study of polymorphic human xenobiotic-metabolizing enzymes.
    Longuemaux S; Deloménie C; Gallou C; Méjean A; Vincent-Viry M; Bouvier R; Droz D; Krishnamoorthy R; Galteau MM; Junien C; Béroud C; Dupret JM
    Cancer Res; 1999 Jun; 59(12):2903-8. PubMed ID: 10383153
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. An analysis of phenotypic variation in the familial cancer syndrome von Hippel-Lindau disease: evidence for modifier effects.
    Webster AR; Richards FM; MacRonald FE; Moore AT; Maher ER
    Am J Hum Genet; 1998 Oct; 63(4):1025-35. PubMed ID: 9758595
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Renal clearance, tissue distribution, and CA-125 responses in a phase I trial of suramin.
    Hutson PR; Tutsch KD; Rago R; Arzoomanian R; Alberti D; Pomplun M; Church D; Marnocha R; Cheng AL; Kehrli N; Wilding G
    Clin Cancer Res; 1998 Jun; 4(6):1429-36. PubMed ID: 9626459
    [TBL] [Abstract] [Full Text] [Related]  


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