BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Kidney tumors AND EPAS1, MOP2, 2034, ENSG00000116016, PASD2, HIF2A, Q99814
54 results:

  • 1. Boosting Clear Cell Renal Carcinoma-Specific Drug Discovery Using a Deep Learning Algorithm and Single-Cell Analysis.
    Wang Y; Chen X; Tang N; Guo M; Ai D
    Int J Mol Sci; 2024 Apr; 25(7):. PubMed ID: 38612943
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway.
    Huang B; Ren J; Ma Q; Yang F; Pan X; Zhang Y; Liu Y; Wang C; Zhang D; Wei L; Ran L; Zhao H; Liang C; Wang X; Wang S; Li H; Ning H; Ran A; Li W; Wang Y; Xiao B
    Mol Cancer; 2024 Feb; 23(1):34. PubMed ID: 38360682
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Genitourinary cancers updates: highlights from ASCO 2023.
    Qin Q; Sheffield H; Taasan SM; Wang AZ; Zhang T
    J Hematol Oncol; 2023 Nov; 16(1):112. PubMed ID: 37990343
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  • 4. Hypoxia-inducible factor 2α protein and mRNA expression correlate with histomorphological features in clear cell renal cell carcinoma.
    Pham T; Ohe C; Yoshida T; Nakamoto T; Kinoshita H; Tsuta K
    Pathol Res Pract; 2023 Nov; 251():154841. PubMed ID: 37826874
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Selective hif2a Inhibitors in the Management of Clear Cell Renal Cancer and Von Hippel-Lindau-Disease-Associated tumors.
    Suárez C; Vieito M; Valdivia A; González M; Carles J
    Med Sci (Basel); 2023 Jun; 11(3):. PubMed ID: 37489462
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2α to prolyl hydroxylase domain 2.
    Figg WD; Fiorini G; Chowdhury R; Nakashima Y; Tumber A; McDonough MA; Schofield CJ
    Proteins; 2023 Nov; 91(11):1510-1524. PubMed ID: 37449559
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. [Precision oncology options in urological cancers].
    Franz A; Plage H; Fendler A; Schlomm T; Kornienko K
    Urologie; 2023 Jul; 62(7):696-704. PubMed ID: 37294331
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Comprehensive
    Karaghiannis V; Maric D; Garrec C; Maaziz N; Buffet A; Schmitt L; Antunes V; Airaud F; Aral B; Le Roy A; Corbineau S; Mansour-Hendili L; Lesieur V; Rimbert A; Laporte F; Delamare M; Rab M; Bézieau S; Cassinat B; Galacteros F; Gimenez-Roqueplo AP; Burnichon N; Cario H; Van Wijk R; Bento C; Girodon F; Hoogewijs D; Gardie B
    Haematologica; 2023 Jun; 108(6):1652-1666. PubMed ID: 36700397
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Epigenomic charting and functional annotation of risk loci in renal cell carcinoma.
    Nassar AH; Abou Alaiwi S; Baca SC; Adib E; Corona RI; Seo JH; Fonseca MAS; Spisak S; El Zarif T; Tisza V; Braun DA; Du H; He M; Flaifel A; Alchoueiry M; Denize T; Matar SG; Acosta A; Shukla S; Hou Y; Steinharter J; Bouchard G; Berchuck JE; O'Connor E; Bell C; Nuzzo PV; Mary Lee GS; Signoretti S; Hirsch MS; Pomerantz M; Henske E; Gusev A; Lawrenson K; Choueiri TK; Kwiatkowski DJ; Freedman ML
    Nat Commun; 2023 Jan; 14(1):346. PubMed ID: 36681680
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. CD70-Targeted Micelles Enhance HIF2α siRNA Delivery and Inhibit Oncogenic Functions in Patient-Derived Clear Cell Renal Carcinoma Cells.
    Trac N; Oh HS; Jones LI; Caliliw R; Ohtake S; Shuch B; Chung EJ
    Molecules; 2022 Dec; 27(23):. PubMed ID: 36500549
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Hypoxia-Inducible Factor 2 Alpha (HIF2α) Inhibitors: Targeting Genetically Driven Tumor Hypoxia.
    Toledo RA; Jimenez C; Armaiz-Pena G; Arenillas C; Capdevila J; Dahia PLM
    Endocr Rev; 2023 Mar; 44(2):312-322. PubMed ID: 36301191
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Molecular analysis and favorable clinical outcomes in real-world patients with metastatic renal cell carcinoma.
    Donskov F; Pinto CA; Predoiu R; Fox C; Georgsen JB; Skaarup K; Burcu M; Perini R; Steiniche T
    Acta Oncol; 2022 Oct; 61(10):1268-1277. PubMed ID: 36112410
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer.
    Sugimoto Y; Ratcliffe PJ
    Nat Struct Mol Biol; 2022 Sep; 29(9):871-880. PubMed ID: 36097292
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Hypoxia-inducible factor pathway genes predict survival in metastatic clear cell renal cell carcinoma.
    Tamukong PK; Kuhlmann P; You S; Su S; Wang Y; Yoon S; Gong J; Figlin RA; Janes JL; Freedland SJ; Halabi S; Small EJ; Rini BI; Kim HL
    Urol Oncol; 2022 Nov; 40(11):495.e1-495.e10. PubMed ID: 35973929
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Organophosphate flame retardant TDCPP: A risk factor for renal cancer?
    Zhou X; Zhou X; Yao L; Zhang X; Cong R; Luan J; Zhang T; Song N
    Chemosphere; 2022 Oct; 305():135485. PubMed ID: 35764118
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer.
    Patel SA; Hirosue S; Rodrigues P; Vojtasova E; Richardson EK; Ge J; Syafruddin SE; Speed A; Papachristou EK; Baker D; Clarke D; Purvis S; Wesolowski L; Dyas A; Castillon L; Caraffini V; Bihary D; Yong C; Harrison DJ; Stewart GD; Machiela MJ; Purdue MP; Chanock SJ; Warren AY; Samarajiwa SA; Carroll JS; Vanharanta S
    Nature; 2022 Jun; 606(7916):999-1006. PubMed ID: 35676472
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Immunohistochemical expression of carbonic anhydrase 9, glucose transporter 1, and paired box 8 in von Hippel-Lindau disease-related lesions.
    Chatzopoulos K; Aubry MC; Gupta S
    Hum Pathol; 2022 May; 123():93-101. PubMed ID: 35196526
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner.
    Zhou M; Leung JY; Gessner KH; Hepperla AJ; Simon JM; Davis IJ; Kim WY
    Cancer Immunol Res; 2022 Mar; 10(3):285-290. PubMed ID: 35013001
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Expression and prognostic significance of EPAS-1 in renal clear cell carcinoma.
    Chen B; Wang L; Zhao J; Tan C; Zhao P
    Ann Ital Chir; 2021; 92():671-675. PubMed ID: 34807005
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. A drug repositioning success: The repositioned therapeutic applications and mechanisms of action of thalidomide.
    Amare GG; Meharie BG; Belayneh YM
    J Oncol Pharm Pract; 2021 Apr; 27(3):673-678. PubMed ID: 33249990
    [TBL] [Abstract] [Full Text] [Related]  


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