BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Kidney tumors AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884 AND Treatment
15 results:

  • 1. Combined BRAF, MEK, and heat-shock protein 90 inhibition in advanced BRAF V600-mutant melanoma.
    Eroglu Z; Chen YA; Smalley I; Li J; Markowitz JK; Brohl AS; Tetteh L; Taylor H; Sondak VK; Khushalani NI; Smalley KSM
    Cancer; 2024 Jan; 130(2):232-243. PubMed ID: 37776537
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Identification of an immunogenic cell death-related gene signature predicts survival and sensitivity to immunotherapy in clear cell renal carcinoma.
    Zhou S; Lu Y; Chen Y; Gan W
    Sci Rep; 2023 Mar; 13(1):4449. PubMed ID: 36932108
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Hypoxia-inducible factor pathway genes predict survival in metastatic clear cell renal cell carcinoma.
    Tamukong PK; Kuhlmann P; You S; Su S; Wang Y; Yoon S; Gong J; Figlin RA; Janes JL; Freedland SJ; Halabi S; Small EJ; Rini BI; Kim HL
    Urol Oncol; 2022 Nov; 40(11):495.e1-495.e10. PubMed ID: 35973929
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell Carcinoma.
    Pahwa R; Dubhashi J; Singh A; Jailwala P; Lobanov A; Thomas CJ; Ceribelli M; Wilson K; Ricketts CJ; Vocke CD; Wells C; Bottaro DP; Linehan WM; Neckers L; Srinivasan R
    J Exp Clin Cancer Res; 2022 Jun; 41(1):208. PubMed ID: 35754026
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Sildenafil triggers tumor lethality through altered expression of hsp90 and degradation of PKD2.
    Chen L; Liu Y; Becher A; Diepold K; Schmid E; Fehn A; Brunner C; Rouhi A; Chiosis G; Cronauer M; Seufferlein T; Azoitei N
    Carcinogenesis; 2020 Oct; 41(10):1421-1431. PubMed ID: 31917403
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma.
    Khan Z; Khan AA; Yadav H; Prasad GBKS; Bisen PS
    Cell Mol Biol Lett; 2017; 22():8. PubMed ID: 28536639
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation.
    Henrich CJ; Brooks AD; Erickson KL; Thomas CL; Bokesch HR; Tewary P; Thompson CR; Pompei RJ; Gustafson KR; McMahon JB; Sayers TJ
    Cell Death Dis; 2015 Feb; 6(2):e1666. PubMed ID: 25719250
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Combination treatment of renal cell carcinoma with belinostat and 5-fluorouracil: a role for oxidative stress induced DNA damage and hsp90 regulated thymidine synthase.
    Kim MJ; Lee JS; Park SE; Yi HJ; Jeong IG; Kang JS; Yun J; Lee JY; Ro S; Lee JS; Choi EK; Hwang JJ; Kim CS
    J Urol; 2015 May; 193(5):1660-8. PubMed ID: 25433307
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.
    Kang SA; Cho HS; Yoon JB; Chung IK; Lee ST
    Biochem J; 2012 Oct; 447(2):313-20. PubMed ID: 22849407
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. 17-Allylamino-17-demethoxygeldanamycin and ritonavir inhibit renal cancer growth by inhibiting the expression of heat shock factor-1.
    Sato A; Asano T; Ito K; Asano T
    Int J Oncol; 2012 Jul; 41(1):46-52. PubMed ID: 22470109
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Biodistribution of HPMA copolymer-aminohexylgeldanamycin-RGDfK conjugates for prostate cancer drug delivery.
    Borgman MP; Aras O; Geyser-Stoops S; Sausville EA; Ghandehari H
    Mol Pharm; 2009; 6(6):1836-47. PubMed ID: 19743884
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. A phase II trial of 17-(Allylamino)-17-demethoxygeldanamycin in patients with papillary and clear cell renal cell carcinoma.
    Ronnen EA; Kondagunta GV; Ishill N; Sweeney SM; Deluca JK; Schwartz L; Bacik J; Motzer RJ
    Invest New Drugs; 2006 Nov; 24(6):543-6. PubMed ID: 16832603
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and hsp90 complex in human colonic epithelial cells.
    Park KA; Byun HS; Won M; Yang KJ; Shin S; Piao L; Kim JM; Yoon WH; Junn E; Park J; Seok JH; Hur GM
    Carcinogenesis; 2007 Jan; 28(1):71-80. PubMed ID: 16774932
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. High expression of the Cap43 gene in infiltrating macrophages of human renal cell carcinomas.
    Nishie A; Masuda K; Otsubo M; Migita T; Tsuneyoshi M; Kohno K; Shuin T; Naito S; Ono M; Kuwano M
    Clin Cancer Res; 2001 Jul; 7(7):2145-51. PubMed ID: 11448934
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt.
    Lees MJ; Whitelaw ML
    Mol Cell Biol; 1999 Aug; 19(8):5811-22. PubMed ID: 10409767
    [TBL] [Abstract] [Full Text] [Related]  


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