BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Kidney tumors AND JAK1, ENSG00000162434, P23458, JTK3, JAK1B, JAK1A, 3716
19 results:

  • 1. Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma.
    Lin H; Fu L; Li P; Zhu J; Xu Q; Wang Y; Mumin MA; Zhou X; Chen Y; Shu G; Yao G; Chen M; Lu J; Zhang L; Liu Y; Zhao Y; Bao J; Chen W; Luo J; Li X; Chen Z; Cao J
    J Transl Med; 2023 May; 21(1):343. PubMed ID: 37221577
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing jak1.
    Pan Y; Shu G; Fu L; Huang K; Zhou X; Gui C; Liu H; Jin X; Chen M; Li P; Cen J; Feng Z; Lu J; Chen Z; Li J; Xu Q; Wang Y; Liang H; Wang Z; Deng Q; Chen W; Luo J; Yang J; Zhang J; Wei J
    Adv Sci (Weinh); 2023 Apr; 10(11):e2206792. PubMed ID: 36775874
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study.
    Verstovsek S; Gerds AT; Vannucchi AM; Al-Ali HK; Lavie D; Kuykendall AT; Grosicki S; Iurlo A; Goh YT; Lazaroiu MC; Egyed M; Fox ML; McLornan D; Perkins A; Yoon SS; Gupta V; Kiladjian JJ; Granacher N; Lee SE; Ocroteala L; Passamonti F; Harrison CN; Klencke BJ; Ro S; Donahue R; Kawashima J; Mesa R;
    Lancet; 2023 Jan; 401(10373):269-280. PubMed ID: 36709073
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Circ_0000274 contributes to renal cell carcinoma progression by regulating miR-338-3p/NUCB2 axis and jak1/STAT3 pathway.
    Qi Q; Sun Y; Yang Y; Liu Y
    Transpl Immunol; 2022 Oct; 74():101626. PubMed ID: 35569717
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Circular RNA circFNDC3B protects renal carcinoma by miR-99a downregulation.
    Chen T; Yu Q; Shao S; Guo L
    J Cell Physiol; 2020 May; 235(5):4399-4406. PubMed ID: 31637704
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. IL-6 stimulation of DNA replication is jak1/2 mediated in cross-talk with hyperactivated ERK1/2 signaling.
    Subotički T; Mitrović Ajtić O; Beleslin-Čokić BB; Bjelica S; Djikić D; Diklić M; Leković D; Gotić M; Santibanez JF; Noguchi CT; Čokić VP
    Cell Biol Int; 2019 Feb; 43(2):192-206. PubMed ID: 30571852
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma.
    Kim C; Baek SH; Um JY; Shim BS; Ahn KS
    BMC Nephrol; 2016 Feb; 17():19. PubMed ID: 26911335
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Conditional inactivation of the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney.
    Pritchett TL; Bader HL; Henderson J; Hsu T
    Oncogene; 2015 May; 34(20):2631-9. PubMed ID: 25023703
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Phosphorylated signal transducer and activator of transcription 1 is a potential predictor of interferon response in patients with advanced renal cell carcinoma.
    Li W; Wei Q; Liang J
    Mol Med Rep; 2014 May; 9(5):1929-34. PubMed ID: 24626739
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. JAK inhibitors: pharmacology and clinical activity in chronic myeloprolipherative neoplasms.
    Treliński J; Robak T
    Curr Med Chem; 2013; 20(9):1147-61. PubMed ID: 23317159
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Tyrosine kinase expression profile in clear cell renal cell carcinoma.
    Behbahani TE; Thierse C; Baumann C; Holl D; Bastian PJ; von Ruecker A; Müller SC; Ellinger J; Hauser S
    World J Urol; 2012 Aug; 30(4):559-65. PubMed ID: 21969129
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. JAK kinases promote invasiveness in VHL-mediated renal cell carcinoma by a suppressor of cytokine signaling-regulated, HIF-independent mechanism.
    Wu KL; Miao H; Khan S
    Am J Physiol Renal Physiol; 2007 Dec; 293(6):F1836-46. PubMed ID: 17898043
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Defective Jak-Stat activation in renal cell carcinoma is associated with interferon-alpha resistance.
    Shang D; Liu Y; Ito N; Kamoto T; Ogawa O
    Cancer Sci; 2007 Aug; 98(8):1259-64. PubMed ID: 17573897
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. BRCA1 transcriptionally regulates genes involved in breast tumorigenesis.
    Welcsh PL; Lee MK; Gonzalez-Hernandez RM; Black DJ; Mahadevappa M; Swisher EM; Warrington JA; King MC
    Proc Natl Acad Sci U S A; 2002 May; 99(11):7560-5. PubMed ID: 12032322
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Loss of interferon-gamma inducibility of TAP1 and LMP2 in a renal cell carcinoma cell line.
    Dovhey SE; Ghosh NS; Wright KL
    Cancer Res; 2000 Oct; 60(20):5789-96. PubMed ID: 11059775
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Identification of receptor genes in renal cell carcinoma associated with angiogenesis by differential hybridization technique.
    Takahashi A; Sasaki H; Kim SJ; Kakizoe T; Miyao N; Sugimura T; Terada M; Tsukamoto T
    Biochem Biophys Res Commun; 1999 Apr; 257(3):855-9. PubMed ID: 10208873
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Molecular analysis of the IL-2 receptor beta chain gene expressed in human tumor cells.
    Suminami Y; Kashii Y; Law JC; Lin WC; Stanson J; Reichert TE; Rabinowich H; Whiteside TL
    Oncogene; 1998 Mar; 16(10):1309-17. PubMed ID: 9546432
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Urokinase receptor is associated with the components of the jak1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598.
    Koshelnick Y; Ehart M; Hufnagl P; Heinrich PC; Binder BR
    J Biol Chem; 1997 Nov; 272(45):28563-7. PubMed ID: 9353320
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Tumor-induced suppression of T lymphocyte proliferation coincides with inhibition of Jak3 expression and IL-2 receptor signaling: role of soluble products from human renal cell carcinomas.
    Kolenko V; Wang Q; Riedy MC; O'Shea J; Ritz J; Cathcart MK; Rayman P; Tubbs R; Edinger M; Novick A; Bukowski R; Finke J
    J Immunol; 1997 Sep; 159(6):3057-67. PubMed ID: 9300731
    [TBL] [Abstract] [Full Text] [Related]  


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