BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Kidney tumors AND uPA
66 results:

  • 1. The expression of urokinase-type plasminogen activator system in upper tract urothelial carcinoma and its prognostic value after radical nephroureterectomy.
    Abufaraj M; Kimura S; Haitel A; Iwata T; Isleem U; D'Andrea D; Soria F; Mori K; Rink M; Bensalah K; Rouprêt M; Margulis V; Briganti A; Karakiewicz PI; Shariat SF
    Urol Oncol; 2020 Aug; 38(8):685.e17-685.e25. PubMed ID: 32381392
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Calcitriol inhibits migration and invasion of renal cell carcinoma cells by suppressing Smad2/3-, STAT3- and β-catenin-mediated epithelial-mesenchymal transition.
    Xu S; Zhang ZH; Fu L; Song J; Xie DD; Yu DX; Xu DX; Sun GP
    Cancer Sci; 2020 Jan; 111(1):59-71. PubMed ID: 31729097
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.
    Liou YF; Hsieh YS; Hung TW; Chen PN; Chang YZ; Kao SH; Lin SW; Chang HR
    Int J Med Sci; 2019; 16(5):686-695. PubMed ID: 31217736
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Bismaleimide cross-linked anthrax toxin forms functional octamers with high specificity in tumor targeting.
    Fischer ES; Campbell WA; Liu S; Ghirlando R; Fattah RJ; Bugge TH; Leppla SH
    Protein Sci; 2019 Jun; 28(6):1059-1070. PubMed ID: 30942916
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in Madin-Darby canine kidney cells.
    Oyanadel C; Holmes C; Pardo E; Retamal C; Shaughnessy R; Smith P; Cortés P; Bravo-Zehnder M; Metz C; Feuerhake T; Romero D; Roa JC; Montecinos V; Soza A; González A
    Mol Biol Cell; 2018 Mar; 29(5):557-574. PubMed ID: 29298841
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231.
    Liu X; Liu X; Sunchen S; Liu M; Shen C; Wu J; Zhao W; Yu B; Liu J
    Drug Deliv; 2017 Nov; 24(1):1811-1817. PubMed ID: 29172777
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Urokinase-type plasminogen activator (upa) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
    Stepanova V; Dergilev KV; Holman KR; Parfyonova YV; Tsokolaeva ZI; Teter M; Atochina-Vasserman EN; Volgina A; Zaitsev SV; Lewis SP; Zabozlaev FG; Obraztsova K; Krymskaya VP; Cines DB
    J Biol Chem; 2017 Dec; 292(50):20528-20543. PubMed ID: 28972182
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Identification of pancreatic tumors in vivo with ligand-targeted, pH responsive mesoporous silica nanoparticles by multispectral optoacoustic tomography.
    Gurka MK; Pender D; Chuong P; Fouts BL; Sobelov A; McNally MW; Mezera M; Woo SY; McNally LR
    J Control Release; 2016 Jun; 231():60-7. PubMed ID: 26763377
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Components of the Plasminogen-Plasmin System as Biologic Markers for Cancer.
    McMahon BJ; Kwaan HC
    Adv Exp Med Biol; 2015; 867():145-56. PubMed ID: 26530365
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Protease-activated receptor 2 enhances renal cell carcinoma cell invasion and migration via PI3K/AKT signaling pathway.
    Sun Z; Cao B; Wu J
    Exp Mol Pathol; 2015 Jun; 98(3):382-9. PubMed ID: 25773677
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Antitumor effect and mechanism of action of a tumor-targeting recombinant human tumor necrosis factor-α fusion protein mediated by urokinase.
    Dai YC; Yang SM; Wang X; Zhou YJ; Hou G; Huang DN
    Mol Med Rep; 2015 Jun; 11(6):4333-40. PubMed ID: 25672264
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Prognostic impact of urokinase-type plasminogen activator system components in clear cell renal cell carcinoma patients without distant metastasis.
    Fuessel S; Erdmann K; Taubert H; Lohse-Fischer A; Zastrow S; Meinhardt M; Bluemke K; Hofbauer L; Fornara P; Wullich B; Baretton G; Magdolen V; Wirth MP; Kotzsch M
    BMC Cancer; 2014 Dec; 14():974. PubMed ID: 25519168
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo.
    Sun Y; Wang X; Zhou Q; Lu Y; Zhang H; Chen Q; Zhao M; Su S
    Oncol Rep; 2015 Jan; 33(1):338-46. PubMed ID: 25370743
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Reduced gene expression of bikunin as a prognostic marker for renal cell carcinoma.
    Bayraktar E; Igci M; Erturhan S; Igci YZ; Karakok M; Gogebakan B; Ulasli M; Cakmak EA; Arslan A
    Exp Oncol; 2014 Jun; 36(2):107-11. PubMed ID: 24980765
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Urokinase gene 3'-UTR T/C polymorphism is associated with malignancy and ESRD in idiopathic membranous nephropathy.
    Chen CH; Chen SY; Shu KH; Wen MC; Cheng CH; Wu MJ; Yu TM; Chuang YW; Tsai FJ
    Biomed Res Int; 2014; 2014():425095. PubMed ID: 24822208
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma.
    Weissinger D; Tagscherer KE; Macher-Göppinger S; Haferkamp A; Wagener N; Roth W
    Mol Cancer; 2013 Oct; 12(1):120. PubMed ID: 24107265
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The apparent upa/PAI-1 paradox in cancer: more than meets the eye.
    Kwaan HC; Mazar AP; McMahon BJ
    Semin Thromb Hemost; 2013 Jun; 39(4):382-91. PubMed ID: 23532574
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Baicalin suppresses migration, invasion and metastasis of breast cancer via p38MAPK signaling pathway.
    Wang XF; Zhou QM; Du J; Zhang H; Lu YY; Su SB
    Anticancer Agents Med Chem; 2013 Jul; 13(6):923-31. PubMed ID: 23387975
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. BreastDefend™ prevents breast-to-lung cancer metastases in an orthotopic animal model of triple-negative human breast cancer.
    Jiang J; Thyagarajan-Sahu A; Loganathan J; Eliaz I; Terry C; Sandusky GE; Sliva D
    Oncol Rep; 2012 Oct; 28(4):1139-45. PubMed ID: 22842551
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. PKD2 and PKD3 promote prostate cancer cell invasion by modulating NF-κB- and HDAC1-mediated expression and activation of upa.
    Zou Z; Zeng F; Xu W; Wang C; Ke Z; Wang QJ; Deng F
    J Cell Sci; 2012 Oct; 125(Pt 20):4800-11. PubMed ID: 22797919
    [TBL] [Abstract] [Full Text] [Related]  


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