Terms: = Leukemia AND AFF4, Q9UHB7, 27125, ENSG00000072364, AF5Q31, MCEF
34 results:
1. Multiple Genomic Alterations, Including a Novel
Sahin Y; Wang YL; Pei J; Mansoor N; Styler M; Testa JR; Nejati R
Int J Mol Sci; 2023 Dec; 25(1):. PubMed ID: 38203475
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2. aff4 globally affects the release of paused RNA polymerase II in HEL cells.
Yang ZM; Zhang G; Wei G; Jing LL; Yu M
Yi Chuan; 2023 Aug; 45(8):658-668. PubMed ID: 37609817
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3. PI3K/ c-Myc/aff4 axis promotes pancreatic tumorigenesis through fueling nucleotide metabolism.
Ni C; Liu W; Zheng K; Guo S; Song B; Jing W; Li G; Li B; Ni C; Shi K; Jin G; Yu G
Int J Biol Sci; 2023; 19(6):1968-1982. PubMed ID: 37063434
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4. Unexpected appearance of KMT2A::MLLT10 fusion transcript in acute myeloid leukemia with t(5;11)(q31;q23.3).
Yamamoto K; Matsumoto H; Matsumoto S; Sakai R; Kitao A; Watanabe M; Goto H; Sugimoto T; Yano Y; Yakushijin K; Minami H
Cancer Genet; 2023 Apr; 272-273():41-46. PubMed ID: 36774707
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5. A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth.
Li X; Yao Y; Wu F; Song Y
J Hematol Oncol; 2022 Apr; 15(1):41. PubMed ID: 35395864
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6. aff4 facilitates melanoma cell progression by regulating c-Jun activity.
Hu H; Zhang Y; Zhao L; Zhao W; Wang X; Ye E; Dong Y; Zhang L; Ran F; Zhou Y; Huang Y
Exp Cell Res; 2021 Feb; 399(2):112445. PubMed ID: 33417923
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7. aff4 enhances odontogenic differentiation of human dental pulp cells.
Zhang Y; Xiao Q; Wu Z; Xu R; Zou S; Zhou C
Biochem Biophys Res Commun; 2020 May; 525(3):687-692. PubMed ID: 32139123
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8. Genetic Disorders in Prenatal Onset Syndromic Short Stature Identified by Exome Sequencing.
Homma TK; Freire BL; Honjo Kawahira RS; Dauber A; Funari MFA; Lerario AM; Nishi MY; Albuquerque EV; Vasques GA; Collett-Solberg PF; Miura Sugayama SM; Bertola DR; Kim CA; Arnhold IJP; Malaquias AC; Jorge AAL
J Pediatr; 2019 Dec; 215():192-198. PubMed ID: 31630891
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9. aff4 promotes tumorigenesis and tumor-initiation capacity of head and neck squamous cell carcinoma cells by regulating SOX2.
Deng P; Wang J; Zhang X; Wu X; Ji N; Li J; Zhou M; Jiang L; Zeng X; Chen Q
Carcinogenesis; 2018 Jul; 39(7):937-947. PubMed ID: 29741610
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10. All-trans retinoic acid combined with 5-Aza-2'-deoxycitidine induces C/EBPα expression and growth inhibition in MLL-AF9-positive leukemic cells.
Fujiki A; Imamura T; Sakamoto K; Kawashima S; Yoshida H; Hirashima Y; Miyachi M; Yagyu S; Nakatani T; Sugita K; Hosoi H
Biochem Biophys Res Commun; 2012 Nov; 428(2):216-23. PubMed ID: 23063977
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11. Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation factor VII gene expression.
Suzuki A; Miyawaki Y; Okuyama E; Murata M; Ando Y; Kato I; Takagi Y; Takagi A; Murate T; Saito H; Kojima T
Biochem J; 2013 Jan; 449(1):231-9. PubMed ID: 23050902
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12. The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output.
Luo Z; Lin C; Guest E; Garrett AS; Mohaghegh N; Swanson S; Marshall S; Florens L; Washburn MP; Shilatifard A
Mol Cell Biol; 2012 Jul; 32(13):2608-17. PubMed ID: 22547686
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13. ELL facilitates RNA polymerase II pause site entry and release.
Byun JS; Fufa TD; Wakano C; Fernandez A; Haggerty CM; Sung MH; Gardner K
Nat Commun; 2012 Jan; 3():633. PubMed ID: 22252557
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14. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Biswas D; Milne TA; Basrur V; Kim J; Elenitoba-Johnson KS; Allis CD; Roeder RG
Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15751-6. PubMed ID: 21896721
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15. Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.
He N; Chan CK; Sobhian B; Chou S; Xue Y; Liu M; Alber T; Benkirane M; Zhou Q
Proc Natl Acad Sci U S A; 2011 Sep; 108(36):E636-45. PubMed ID: 21873227
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16. Identification of copy number alterations by array comparative genomic hybridization in patients with late chronic or accelerated phase chronic myeloid leukemia treated with imatinib mesylate.
Nadarajan VS; Phan CL; Ang CH; Liang KL; Gan GG; Bee PC; Zakaria Z
Int J Hematol; 2011 Apr; 93(4):465-473. PubMed ID: 21387093
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17. Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.
Melko M; Douguet D; Bensaid M; Zongaro S; Verheggen C; Gecz J; Bardoni B
Hum Mol Genet; 2011 May; 20(10):1873-85. PubMed ID: 21330300
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18. MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
Monroe SC; Jo SY; Sanders DS; Basrur V; Elenitoba-Johnson KS; Slany RK; Hess JL
Exp Hematol; 2011 Jan; 39(1):77-86.e1-5. PubMed ID: 20854876
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19. HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.
Sobhian B; Laguette N; Yatim A; Nakamura M; Levy Y; Kiernan R; Benkirane M
Mol Cell; 2010 May; 38(3):439-51. PubMed ID: 20471949
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20. Activation of Ras-dependent Elk-1 activity by MLL-AF4 family fusion oncoproteins.
Ng MH; Ng RK; Kong CT; Jin DY; Chan LC
Exp Hematol; 2010 Jun; 38(6):481-8. PubMed ID: 20362031
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