Terms: = Leukemia AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Clinical Outcome
31 results:
1. [clinical and molecular characteristics and prognosis of classical hairy cell leukemia and hairy cell leukemia variant].
Wei C; Jin XX; Cai H; Wang X; Zhuang JL; Zhou DB
Zhonghua Nei Ke Za Zhi; 2023 Apr; 62(4):416-421. PubMed ID: 37032137
[No Abstract] [Full Text] [Related]
2. Simvastatin potentiates the cell-killing activity of imatinib in imatinib-resistant chronic myeloid leukemia cells mainly through PI3K/akt pathway attenuation and Myc downregulation.
Ding L; Chen Q; Chen K; Jiang Y; Li G; Chen Q; Bai D; Gao D; Deng M; Zhang H; Xu B
Eur J Pharmacol; 2021 Dec; 913():174633. PubMed ID: 34843676
[TBL] [Abstract] [Full Text] [Related]
3. The protein landscape of chronic lymphocytic leukemia.
Meier-Abt F; Lu J; Cannizzaro E; Pohly MF; Kummer S; Pfammatter S; Kunz L; Collins BC; Nadeu F; Lee KS; Xue P; Gwerder M; Roiss M; Hüllein J; Scheinost S; Dietrich S; Campo E; Huber W; Aebersold R; Zenz T
Blood; 2021 Dec; 138(24):2514-2525. PubMed ID: 34189564
[TBL] [Abstract] [Full Text] [Related]
4. Targeted inhibition of cooperative mutation- and therapy-induced akt activation in AML effectively enhances response to chemotherapy.
Estruch M; Reckzeh K; Vittori C; Centio A; Ali M; Engelhard S; Zhao L; Won KJ; Liu P; Porse BT; Theilgaard-Mönch K
Leukemia; 2021 Jul; 35(7):2030-2042. PubMed ID: 33299144
[TBL] [Abstract] [Full Text] [Related]
5. NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia.
Thomé CH; Ferreira GA; Pereira-Martins DA; Dos Santos GA; Ortiz CA; de Souza LEB; Sobral LM; Silva CLA; Scheucher PS; Gil CD; Leopoldino AM; Silveira DRA; Coelho-Silva JL; Traina F; Koury LC; Melo RAM; Bittencourt R; Pagnano K; Pasquini R; Nunes EC; Fagundes EM; Gloria ABF; Kerbauy FR; Chauffaille ML; Keating A; Tallman MS; Ribeiro RC; Dillon R; Ganser A; Löwenberg B; Valk P; Lo-Coco F; Sanz MA; Berliner N; Faça VM; Rego EM
Sci Rep; 2020 Jun; 10(1):10315. PubMed ID: 32587277
[TBL] [Abstract] [Full Text] [Related]
6. Targeting steroid resistance in T-cell acute lymphoblastic leukemia.
De Smedt R; Morscio J; Goossens S; Van Vlierberghe P
Blood Rev; 2019 Nov; 38():100591. PubMed ID: 31353059
[TBL] [Abstract] [Full Text] [Related]
7.
Zhou JD; Li XX; Zhang TJ; Xu ZJ; Zhang ZH; Gu Y; Wen XM; Zhang W; Ji RB; Deng ZQ; Lin J; Qian J
Aging (Albany NY); 2019 May; 11(10):3376-3391. PubMed ID: 31147526
[No Abstract] [Full Text] [Related]
8. Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML.
Saenz DT; Fiskus W; Manshouri T; Mill CP; Qian Y; Raina K; Rajapakshe K; Coarfa C; Soldi R; Bose P; Borthakur G; Kadia TM; Khoury JD; Masarova L; Nowak AJ; Sun B; Saenz DN; Kornblau SM; Horrigan S; Sharma S; Qiu P; Crews CM; Verstovsek S; Bhalla KN
Leukemia; 2019 Jun; 33(6):1373-1386. PubMed ID: 30575820
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9. Inhibition of maternal embryonic leucine zipper kinase with OTSSP167 displays potent anti-leukemic effects in chronic lymphocytic leukemia.
Zhang Y; Zhou X; Li Y; Xu Y; Lu K; Li P; Wang X
Oncogene; 2018 Oct; 37(41):5520-5533. PubMed ID: 29895969
[TBL] [Abstract] [Full Text] [Related]
10. Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia.
Papaioannou D; Shen C; Nicolet D; McNeil B; Bill M; Karunasiri M; Burke MH; Ozer HG; Yilmaz SA; Zitzer N; Behbehani GK; Oakes CC; Steiner DJ; Marcucci G; Powell BL; Kolitz JE; Carter TH; Wang ES; Mrózek K; Croce CM; Caligiuri MA; Bloomfield CD; Garzon R; Dorrance AM
Proc Natl Acad Sci U S A; 2017 Jun; 114(23):E4641-E4647. PubMed ID: 28533390
[TBL] [Abstract] [Full Text] [Related]
11. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic leukemia: A Genome Sequencing Study.
Li Y; Buijs-Gladdines JG; Canté-Barrett K; Stubbs AP; Vroegindeweij EM; Smits WK; van Marion R; Dinjens WN; Horstmann M; Kuiper RP; Buijsman RC; Zaman GJ; van der Spek PJ; Pieters R; Meijerink JP
PLoS Med; 2016 Dec; 13(12):e1002200. PubMed ID: 27997540
[TBL] [Abstract] [Full Text] [Related]
12. The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and clinical outcome in Acute Lymphoblastic leukemia.
Chen D; Zheng J; Gerasimcik N; Lagerstedt K; Sjögren H; Abrahamsson J; Fogelstrand L; Mårtensson IL
PLoS One; 2016; 11(9):e0162638. PubMed ID: 27611867
[TBL] [Abstract] [Full Text] [Related]
13. EZH2 is increased in paediatric T-cell acute lymphoblastic leukemia and is a suitable molecular target in combination treatment approaches.
D'Angelo V; Iannotta A; Ramaglia M; Lombardi A; Zarone MR; Desiderio V; Affinita MC; Pecoraro G; Di Martino M; Indolfi P; Casale F; Caraglia M
J Exp Clin Cancer Res; 2015 Aug; 34(1):83. PubMed ID: 26268310
[TBL] [Abstract] [Full Text] [Related]
14. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms.
Yang L; Zhang S; George SK; Teng R; You X; Xu M; Liu H; Sun X; Amin HM; Shi W
Oncotarget; 2015 Jun; 6(17):14953-69. PubMed ID: 25879451
[TBL] [Abstract] [Full Text] [Related]
15. HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion.
Feng Y; Xu X; Zhang Y; Ding J; Wang Y; Zhang X; Wu Z; Kang L; Liang Y; Zhou L; Song S; Zhao K; Ye Q
Sci Rep; 2015 Mar; 5():9429. PubMed ID: 25800793
[TBL] [Abstract] [Full Text] [Related]
16. INPP4B overexpression is associated with poor clinical outcome and therapy resistance in acute myeloid leukemia.
Dzneladze I; He R; Woolley JF; Son MH; Sharobim MH; Greenberg SA; Gabra M; Langlois C; Rashid A; Hakem A; Ibrahimova N; Arruda A; Löwenberg B; Valk PJ; Minden MD; Salmena L
Leukemia; 2015 Jul; 29(7):1485-95. PubMed ID: 25736236
[TBL] [Abstract] [Full Text] [Related]
17. Inhibition of 32Dp210 cells harboring T315I mutation by a novel derivative of emodin correlates with down-regulation of BCR-ABL and its downstream signaling pathways.
Li J; Chen Y; Chen B; Chen C; Qiu B; Zheng Z; Zheng J; Liu T; Wang W; Hu J
J Cancer Res Clin Oncol; 2015 Feb; 141(2):283-93. PubMed ID: 25217883
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18. The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts.
Zabkiewicz J; Pearn L; Hills RK; Morgan RG; Tonks A; Burnett AK; Darley RL
Haematologica; 2014 May; 99(5):858-64. PubMed ID: 24334295
[TBL] [Abstract] [Full Text] [Related]
19. Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression.
Keune WJ; Sims AH; Jones DR; Bultsma Y; Lynch JT; Jirström K; Landberg G; Divecha N
Cancer Res; 2013 Dec; 73(23):6913-25. PubMed ID: 24127122
[TBL] [Abstract] [Full Text] [Related]
20. Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma.
Dong LH; Cheng S; Zheng Z; Wang L; Shen Y; Shen ZX; Chen SJ; Zhao WL
J Hematol Oncol; 2013 Jul; 6():53. PubMed ID: 23866964
[TBL] [Abstract] [Full Text] [Related]
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