Terms: = Leukemia AND ATR, Q13535, 545, ENSG00000175054, MEC1, SCKL, SCKL1, FRP1 AND Prognosis
24 results:
1. Prognostic value and therapeutic targeting of XPO1 in chronic lymphocytic leukemia.
Xu Z; Pan B; Miao Y; Li Y; Qin S; Liang J; Kong Y; Zhang X; Tang J; Xia Y; Zhu H; Wang L; Li J; Wu J; Xu W
Clin Exp Med; 2023 Oct; 23(6):2651-2662. PubMed ID: 36738306
[TBL] [Abstract] [Full Text] [Related]
2. Hes1 Controls Proliferation and Apoptosis in Chronic Lymphoblastic leukemia Cells by Modulating PTEN Expression.
Zhang Q; Zhu Z; Guan J; Hu Y; Zhou W; Ye W; Lin B; Weng S; Chen Y; Zheng C
Mol Biotechnol; 2022 Dec; 64(12):1419-1430. PubMed ID: 35704163
[TBL] [Abstract] [Full Text] [Related]
3. Therapeutic and prognostic insights from the analysis of cancer mutational signatures.
Brady SW; Gout AM; Zhang J
Trends Genet; 2022 Feb; 38(2):194-208. PubMed ID: 34483003
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4. Dissecting the role of TP53 alterations in del(11q) chronic lymphocytic leukemia.
Quijada-Álamo M; Pérez-Carretero C; Hernández-Sánchez M; Rodríguez-Vicente AE; Herrero AB; Hernández-Sánchez JM; Martín-Izquierdo M; Santos-Mínguez S; Del Rey M; González T; Rubio-Martínez A; García de Coca A; Dávila-Valls J; Hernández-Rivas JÁ; Parker H; Strefford JC; Benito R; Ordóñez JL; Hernández-Rivas JM
Clin Transl Med; 2021 Feb; 11(2):e304. PubMed ID: 33634999
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5. DAP Kinase-Related Apoptosis-Inducing Protein Kinase 2 (DRAK2) Is a Key Regulator and Molecular Marker in Chronic Lymphocytic leukemia.
Szoltysek K; Ciardullo C; Zhou P; Walaszczyk A; Willmore E; Rand V; Marshall S; Hall A; J Harrison C; Eswaran J; Soundararajan M
Int J Mol Sci; 2020 Oct; 21(20):. PubMed ID: 33081245
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6. A personalized approach to guide allogeneic stem cell transplantation in younger adults with acute myeloid leukemia.
Fenwarth L; Thomas X; de Botton S; Duployez N; Bourhis JH; Lesieur A; Fortin G; Meslin PA; Yakoub-Agha I; Sujobert P; Dumas PY; Récher C; Lebon D; Berthon C; Michallet M; Pigneux A; Nguyen S; Chantepie S; Vey N; Raffoux E; Celli-Lebras K; Gardin C; Lambert J; Malfuson JV; Caillot D; Maury S; Ducourneau B; Turlure P; Lemasle E; Pautas C; Chevret S; Terré C; Boissel N; Socié G; Dombret H; Preudhomme C; Itzykson R
Blood; 2021 Jan; 137(4):524-532. PubMed ID: 32871585
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7. Anti-Tumour Activity of Glycodendrimer Nanoparticles in a Subcutaneous MEC-1 Xenograft Model of Human Chronic Lymphocytic leukemia.
Ziemba B; Sikorska H; Jander M; Kuncman W; Danilewicz M; Appelhans D; Bryszewska M; Borowiec M; Franiak-Pietryga I
Anticancer Agents Med Chem; 2020; 20(3):325-334. PubMed ID: 31738155
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8. Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair.
Ye J; Zha J; Shi Y; Li Y; Yuan D; Chen Q; Lin F; Fang Z; Yu Y; Dai Y; Xu B
Clin Epigenetics; 2019 Oct; 11(1):137. PubMed ID: 31590682
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9. Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery.
Simonetti G; Padella A; do Valle IF; Fontana MC; Fonzi E; Bruno S; Baldazzi C; Guadagnuolo V; Manfrini M; Ferrari A; Paolini S; Papayannidis C; Marconi G; Franchini E; Zuffa E; Laginestra MA; Zanotti F; Astolfi A; Iacobucci I; Bernardi S; Sazzini M; Ficarra E; Hernandez JM; Vandenberghe P; Cools J; Bullinger L; Ottaviani E; Testoni N; Cavo M; Haferlach T; Castellani G; Remondini D; Martinelli G
Cancer; 2019 Mar; 125(5):712-725. PubMed ID: 30480765
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10. Inhibition of MEK and atr is effective in a B-cell acute lymphoblastic leukemia model driven by
Chu SH; Song EJ; Chabon JR; Minehart J; Matovina CN; Makofske JL; Frank ES; Ross K; Koche RP; Feng Z; Xu H; Krivtsov A; Nussenzweig A; Armstrong SA
Blood Adv; 2018 Oct; 2(19):2478-2490. PubMed ID: 30266823
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11. GLP overexpression is associated with poor prognosis in Chronic Lymphocytic leukemia and its inhibition induces leukemic cell death.
Alves-Silva JC; de Carvalho JL; Rabello DA; Serejo TRT; Rego EM; Neves FAR; Lucena-Araujo AR; Pittella-Silva F; Saldanha-Araujo F
Invest New Drugs; 2018 Oct; 36(5):955-960. PubMed ID: 29855824
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12. The expression of inhibitor of bruton's tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis.
Albano F; Chiurazzi F; Mimmi S; Vecchio E; Pastore A; Cimmino C; Frieri C; Iaccino E; Pisano A; Golino G; Fiume G; Mallardo M; Scala G; Quinto I
Cell Death Dis; 2018 Jan; 9(1):13. PubMed ID: 29317636
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13. NOTCH1 mutations are associated with high CD49d expression in chronic lymphocytic leukemia: link between the NOTCH1 and the NF-κB pathways.
Benedetti D; Tissino E; Pozzo F; Bittolo T; Caldana C; Perini C; Martorelli D; Bravin V; D'Agaro T; Rossi FM; Bomben R; Santinelli E; Zaja F; Pozzato G; Chiarenza A; Di Raimondo F; Del Poeta G; Rossi D; Gaidano G; Dal Bo M; Gattei V; Zucchetto A
Leukemia; 2018 Mar; 32(3):654-662. PubMed ID: 28935990
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14. [The clinical and prognostic significance of acute myeloid leukemia with FLT3-ITD].
Lin D; Wei H; Wang Y; Zhou CL; Liu BC; Liu KQ; Gong BF; Wei SN; Zhang GJ; Liu YT; Gong XY; Qiu SW; Mi YC; Wang JX
Zhonghua Xue Ye Xue Za Zhi; 2016 Dec; 37(12):1017-1021. PubMed ID: 28088961
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15. Mutations in NOTCH1 PEST domain orchestrate CCL19-driven homing of chronic lymphocytic leukemia cells by modulating the tumor suppressor gene DUSP22.
Arruga F; Gizdic B; Bologna C; Cignetto S; Buonincontri R; Serra S; Vaisitti T; Gizzi K; Vitale N; Garaffo G; Mereu E; Diop F; Neri F; Incarnato D; Coscia M; Allan J; Piva R; Oliviero S; Furman RR; Rossi D; Gaidano G; Deaglio S
Leukemia; 2017 Sep; 31(9):1882-1893. PubMed ID: 28017968
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16. Targeting the kinase activities of atr and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.
Morgado-Palacin I; Day A; Murga M; Lafarga V; Anton ME; Tubbs A; Chen HT; Ergan A; Anderson R; Bhandoola A; Pike KG; Barlaam B; Cadogan E; Wang X; Pierce AJ; Hubbard C; Armstrong SA; Nussenzweig A; Fernandez-Capetillo O
Sci Signal; 2016 Sep; 9(445):ra91. PubMed ID: 27625305
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17. Bruton's tyrosine kinase inhibitor restrains Wnt signaling in chronic lymphocytic leukemia.
Li PP; Lu K; Geng LY; Zhou XX; Li XY; Wang X
Mol Med Rep; 2016 Jun; 13(6):4934-8. PubMed ID: 27082823
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18. Prognostic significance of copy number alterations in adolescent and adult patients with precursor B acute lymphoblastic leukemia enrolled in PETHEMA protocols.
Ribera J; Morgades M; Zamora L; Montesinos P; Gómez-Seguí I; Pratcorona M; Sarrà J; Guàrdia R; Nomdedeu J; Tormo M; Martínez-Lopez J; Hernández-Rivas JM; González-Campos J; Barba P; Escoda L; Genescà E; Solé F; Millá F; Feliu E; Ribera JM;
Cancer; 2015 Nov; 121(21):3809-17. PubMed ID: 26194343
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19. Overexpression of IL-9 induced by STAT6 activation promotes the pathogenesis of chronic lymphocytic leukemia.
Chen N; Lu K; Li P; Lv X; Wang X
Int J Clin Exp Pathol; 2014; 7(5):2319-23. PubMed ID: 24966942
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20. [Correlation analysis of FPGS rs10760502G>a polymorphism with prognosis and MTX-related toxicity in pediatric B-cell acute lymphoblastic leukemia].
Liu SG; Gao C; Li ZG; Li WJ; Cui L; Zhao XX; Zheng HY; Wu MY; Zhang RD
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2014 Apr; 22(2):291-7. PubMed ID: 24762994
[TBL] [Abstract] [Full Text] [Related]
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