BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND BAP1, DKFZp686N04275, 8314, ENSG00000163930, Q92560, KIAA0272, hucep-6, HUCEP-13, FLJ37180, FLJ35406
33 results:

  • 1. The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle.
    Aristodemou AEN; Rueda DS; Taylor GP; Bangham CRM
    PLoS Pathog; 2023 Jul; 19(7):e1011494. PubMed ID: 37523412
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Epigenetic targeted therapy of stabilized bap1 in ASXL1 gain-of-function mutated leukemia.
    Wang L; Birch NW; Zhao Z; Nestler CM; Kazmer A; Shilati A; Blake A; Ozark PA; Rendleman EJ; Zha D; Ryan CA; Morgan MAJ; Shilatifard A
    Nat Cancer; 2021 May; 2(5):515-526. PubMed ID: 35122023
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Reducing hyperactivated bap1 attenuates mutant ASXL1-driven myeloid malignancies in human haematopoietic cells.
    Bai J; Chen Z; Chen C; Zhang M; Zhang Y; Song J; Yuan J; Jiang X; Xing W; Yang J; Bai J; Zhou Y
    Cancer Lett; 2021 Oct; 519():78-90. PubMed ID: 34186160
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Gene Expression Analysis of Pediatric Acute Myeloid leukemia Identified a Hyperactive ASXL1/bap1 Axis Linked with Poor Prognosis and over Expressed Epigenetic Modifiers.
    Elyamany G; Akhter A; Kamran H; Rizwan H; Shabani-Rad MT; Alkhayat N; Al Sharif O; Elborai Y; Al Shahrani M; Mansoor A
    Pediatr Hematol Oncol; 2021 Sep; 38(6):581-592. PubMed ID: 33764257
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Tumor-derived neomorphic mutations in ASXL1 impairs the bap1-ASXL1-FOXK1/K2 transcription network.
    Xia YK; Zeng YR; Zhang ML; Liu P; Liu F; Zhang H; He CX; Sun YP; Zhang JY; Zhang C; Song L; Ding C; Tang YJ; Yang Z; Yang C; Wang P; Guan KL; Xiong Y; Ye D
    Protein Cell; 2021 Jul; 12(7):557-577. PubMed ID: 32683582
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors.
    Kroeger C; Roesler R; Wiese S; Hainzl A; Gatzka MV
    Int J Mol Sci; 2020 May; 21(11):. PubMed ID: 32466590
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. [Molecular mechanisms by which the mutant ASXL1/bap1 complex aggravates myeloid leukemia].
    Asada S
    Rinsho Ketsueki; 2020; 61(4):392-405. PubMed ID: 32378586
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Deregulation of tumor suppressive ASXL1-PTEN/AKT axis in myeloid malignancies.
    Cao L; Xia X; Kong Y; Jia F; Yuan B; Li R; Li Q; Wang Y; Cui M; Dai Z; Zheng H; Christensen J; Zhou Y; Wu X
    J Mol Cell Biol; 2020 Sep; 12(9):688-699. PubMed ID: 32236560
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.
    Yamagishi M; Hori M; Fujikawa D; Ohsugi T; Honma D; Adachi N; Katano H; Hishima T; Kobayashi S; Nakano K; Nakashima M; Iwanaga M; Utsunomiya A; Tanaka Y; Okada S; Tsukasaki K; Tobinai K; Araki K; Watanabe T; Uchimaru K
    Cell Rep; 2019 Nov; 29(8):2321-2337.e7. PubMed ID: 31747604
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials.
    Montal R; Andreu-Oller C; Bassaganyas L; Esteban-Fabró R; Moran S; Montironi C; Moeini A; Pinyol R; Peix J; Cabellos L; Villanueva A; Sia D; Mazzaferro V; Esteller M; Llovet JM
    Br J Cancer; 2019 Aug; 121(4):340-343. PubMed ID: 31285588
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase bap1.
    He M; Chaurushiya MS; Webster JD; Kummerfeld S; Reja R; Chaudhuri S; Chen YJ; Modrusan Z; Haley B; Dugger DL; Eastham-Anderson J; Lau S; Dey A; Caothien R; Roose-Girma M; Newton K; Dixit VM
    Science; 2019 Apr; 364(6437):283-285. PubMed ID: 31000662
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The role of ASXL1 in hematopoiesis and myeloid malignancies.
    Asada S; Fujino T; Goyama S; Kitamura T
    Cell Mol Life Sci; 2019 Jul; 76(13):2511-2523. PubMed ID: 30927018
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Aberrant histone modifications induced by mutant ASXL1 in myeloid neoplasms.
    Asada S; Kitamura T
    Int J Hematol; 2019 Aug; 110(2):179-186. PubMed ID: 30515738
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Diverse roles of the E2/E3 hybrid enzyme UBE2O in the regulation of protein ubiquitination, cellular functions, and disease onset.
    Ullah K; Zubia E; Narayan M; Yang J; Xu G
    FEBS J; 2019 Jun; 286(11):2018-2034. PubMed ID: 30468556
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Mutant ASXL1 cooperates with bap1 to promote myeloid leukaemogenesis.
    Asada S; Goyama S; Inoue D; Shikata S; Takeda R; Fukushima T; Yonezawa T; Fujino T; Hayashi Y; Kawabata KC; Fukuyama T; Tanaka Y; Yokoyama A; Yamazaki S; Kozuka-Hata H; Oyama M; Kojima S; Kawazu M; Mano H; Kitamura T
    Nat Commun; 2018 Jul; 9(1):2733. PubMed ID: 30013160
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Transcriptomic rationale for synthetic lethality-targeting ERCC1 and CDKN1A in chronic myelomonocytic leukaemia.
    Hurtado AM; Luengo-Gil G; Chen-Liang TH; Amaral F; Batta K; Palomo L; Lumbreras E; Przychodzen B; Caparros E; Amigo ML; Dıez-Campelo M; Zamora L; Salido Fierrez EJ; Maciejewski JP; Ortuño FJ; Vicente V; Del Canizo M; Sole F; Ferrer-Marin F; Wiseman DH; Jerez A
    Br J Haematol; 2018 Aug; 182(3):373-383. PubMed ID: 29797327
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
    Ricketts CJ; De Cubas AA; Fan H; Smith CC; Lang M; Reznik E; Bowlby R; Gibb EA; Akbani R; Beroukhim R; Bottaro DP; Choueiri TK; Gibbs RA; Godwin AK; Haake S; Hakimi AA; Henske EP; Hsieh JJ; Ho TH; Kanchi RS; Krishnan B; Kwiatkowski DJ; Liu W; Merino MJ; Mills GB; Myers J; Nickerson ML; Reuter VE; Schmidt LS; Shelley CS; Shen H; Shuch B; Signoretti S; Srinivasan R; Tamboli P; Thomas G; Vincent BG; Vocke CD; Wheeler DA; Yang L; Kim WY; Robertson AG; ; Spellman PT; Rathmell WK; Linehan WM
    Cell Rep; 2018 Apr; 23(1):313-326.e5. PubMed ID: 29617669
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Malignant Mesothelioma in Individuals With Nonmesothelial Neoplasms.
    Butnor KJ; Pavlisko EN; Sporn TA; Roggli VL
    Arch Pathol Lab Med; 2018 Jun; 142(6):730-734. PubMed ID: 29528717
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Remodeling of Ca
    Ando H; Kawaai K; Bonneau B; Mikoshiba K
    Adv Biol Regul; 2018 May; 68():64-76. PubMed ID: 29287955
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The Role of Additional Sex Combs-Like Proteins in Cancer.
    Micol JB; Abdel-Wahab O
    Cold Spring Harb Perspect Med; 2016 Oct; 6(10):. PubMed ID: 27527698
    [TBL] [Abstract] [Full Text] [Related]  


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