Terms: = Leukemia AND CCDC6, D10S170, 8030, ENSG00000108091, Q16204, TPC, H4, TST1
267 results:
1. Discovery of novel benzimidazole derivatives as potent HDACs inhibitors against leukemia with (Thio)Hydantoin as zinc-binding moiety: Design, synthesis, enzyme inhibition, and cellular mechanistic study.
Abdulwahab HG; Mansour RE; Farghaly TA; El-Sehrawi HM
Bioorg Chem; 2024 May; 146():107284. PubMed ID: 38493640
[TBL] [Abstract] [Full Text] [Related]
2. Extending MeCP2 interactome: canonical nucleosomal histones interact with MeCP2.
Ortega-Alarcon D; Claveria-Gimeno R; Vega S; Kalani L; Jorge-Torres OC; Esteller M; Ausio J; Abian O; Velazquez-Campoy A
Nucleic Acids Res; 2024 Apr; 52(7):3636-3653. PubMed ID: 38321951
[TBL] [Abstract] [Full Text] [Related]
3. The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells.
Reisbeck L; Linder B; Tascher G; Bozkurt S; Weber KJ; Herold-Mende C; van Wijk SJL; Marschalek R; Schaefer L; Münch C; Kögel D
Am J Physiol Cell Physiol; 2023 Dec; 325(6):C1451-C1469. PubMed ID: 37899749
[TBL] [Abstract] [Full Text] [Related]
4. Spatial Immunoprofiling of Adenoid Cystic Carcinoma Reveals B7-H4 Is a Therapeutic Target for Aggressive Tumors.
Sousa LG; McGrail DJ; Lazar Neto F; Li K; Marques-Piubelli ML; Ferri-Borgogno S; Dai H; Mitani Y; Spardy Burr N; Cooper ZA; Kinneer K; Cortez MA; Lin SY; Bell D; El Naggar A; Burks J; Ferrarotto R
Clin Cancer Res; 2023 Aug; 29(16):3162-3171. PubMed ID: 37256648
[TBL] [Abstract] [Full Text] [Related]
5. First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8.
Fiorentino F; Sementilli S; Menna M; Turrisi F; Tomassi S; Pellegrini FR; Iuzzolino A; D'Acunzo F; Feoli A; Wapenaar H; Taraglio S; Fraschetti C; Del Bufalo D; Sbardella G; Dekker FJ; Paiardini A; Trisciuoglio D; Mai A; Rotili D
J Med Chem; 2023 May; 66(10):6591-6616. PubMed ID: 37155735
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6. [The establishment and multicenter application of internal quality control system for real-time quantitative PCR detection of BCR-ABL (P210) transcript level].
He N; Gu CY; Li QP; Zhou H; Chu LN; Ma DX
Zhonghua Xue Ye Xue Za Zhi; 2022 Jul; 43(7):562-567. PubMed ID: 36709133
[No Abstract] [Full Text] [Related]
7. Circulating mitochondrial DNA is associated with anemia in newly diagnosed hematologic malignancies.
Yue L; Li YH; Ma RL; Niu JW; Cui HT; Sun Y; Yun ZM; Zhuo HL; Wan LM; Li SB; Zhang X; Wu CJ; Hu LD; Tan YX
Leuk Lymphoma; 2023 Jan; 64(1):178-187. PubMed ID: 36260485
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8. Dual inhibition of BCL2L1 and MCL1 is highly effective against RET fusion-positive or MET exon 14 skipping mutation-positive lung adenocarcinoma cells.
Hirai S; Idogawa M; Sumi T; Yamaguchi M; Niki T; Sakuma Y
Biochem Biophys Res Commun; 2022 Nov; 630():24-29. PubMed ID: 36126466
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9. Differential Histone Posttranslational Modifications Induced by DNA Hypomethylating Agents.
Malkaram SA; Shatnawi A; Fan J; Carraway H; Denvir J; Primerano DA; Abd Elmageed ZY; Fandy TE
Cancer Control; 2022; 29():10732748221074051. PubMed ID: 35067084
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10. Drug resistance to nelarabine in leukemia cell lines might be caused by reduced expression of deoxycytidine kinase through epigenetic mechanisms.
Yoshida K; Fujita A; Narazaki H; Asano T; Itoh Y
Cancer Chemother Pharmacol; 2022 Jan; 89(1):83-91. PubMed ID: 34825941
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11. Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1-like (DOT1L) and partnering complexes involved in leukemogenesis.
Stodola TJ; Chi YI; De Assuncao TM; Leverence EN; Tripathi S; Dsouza NR; Mathison AJ; Volkman BF; Smith BC; Lomberk G; Zimmermann MT; Urrutia R
Proteins; 2022 Jan; 90(1):282-298. PubMed ID: 34414607
[TBL] [Abstract] [Full Text] [Related]
12. Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution.
Gao M; Wang J; Rousseaux S; Tan M; Pan L; Peng L; Wang S; Xu W; Ren J; Liu Y; Spinck M; Barral S; Wang T; Chuffart F; Bourova-Flin E; Puthier D; Curtet S; Bargier L; Cheng Z; Neumann H; Li J; Zhao Y; Mi JQ; Khochbin S
Cell Rep; 2021 Jul; 36(4):109460. PubMed ID: 34320364
[TBL] [Abstract] [Full Text] [Related]
13. Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression.
Fang K; Huang W; Sun YM; Chen TQ; Zeng ZC; Yang QQ; Pan Q; Han C; Sun LY; Luo XQ; Wang WT; Chen YQ
Genome Biol; 2020 Nov; 21(1):269. PubMed ID: 33143730
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14. The epigenetic treatment remodel genome-wide histone H4 hyper-acetylation patterns and affect signaling pathways in acute promyelocytic leukemia cells.
Valiulienė G; Vitkevičienė A; Navakauskienė R
Eur J Pharmacol; 2020 Dec; 889():173641. PubMed ID: 33045196
[TBL] [Abstract] [Full Text] [Related]
15. Long non-coding RNA DLEUI promotes papillary thyroid carcinoma progression by sponging miR-421 and increasing ROCK1 expression.
Li R; Wan T; Qu J; Yu Y; Zheng R
Aging (Albany NY); 2020 Sep; 12(20):20127-20138. PubMed ID: 32910787
[TBL] [Abstract] [Full Text] [Related]
16. Combinatorial molecule screening identified a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells.
Hultmark S; Baudet A; Schmiderer L; Prabhala P; Palma-Tortosa S; Sandén C; Fioretos T; Sasidharan R; Larsson C; Lehmann S; Juliusson G; Ek F; Magnusson M
Haematologica; 2021 Oct; 106(10):2566-2577. PubMed ID: 32855276
[TBL] [Abstract] [Full Text] [Related]
17. In situ exploring Chidamide, a histone deacetylase inhibitor, induces molecular changes of leukemic T-lymphocyte apoptosis using Raman spectroscopy.
Xie Y; Tang P; Xing X; Zhao Y; Cao S; Liu S; Lu X; Zhong L
Spectrochim Acta A Mol Biomol Spectrosc; 2020 Nov; 241():118669. PubMed ID: 32653824
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18. Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells.
Fioravanti R; Tomassi S; Di Bello E; Romanelli A; Plateroti AM; Benedetti R; Conte M; Novellino E; Altucci L; Valente S; Mai A
Molecules; 2020 Jul; 25(14):. PubMed ID: 32650558
[TBL] [Abstract] [Full Text] [Related]
19. Crucial Functions of the JMJD1/KDM3 Epigenetic Regulators in Cancer.
Sui Y; Gu R; Janknecht R
Mol Cancer Res; 2021 Jan; 19(1):3-13. PubMed ID: 32605929
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20. Preclinical anticancer studies on the ethyl acetate leaf extracts of Datura stramonium and Datura inoxia.
Nasir B; Baig MW; Majid M; Ali SM; Khan MZI; Kazmi STB; Haq IU
BMC Complement Med Ther; 2020 Jun; 20(1):188. PubMed ID: 32552791
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