Terms: = Leukemia AND CDC73, HRPT2, 79577, ENSG00000134371, HPT-JT, Q6P1J9, FLJ23316, C1orf28
4 results:
1. The PAF1c Subunit cdc73 Is Required for Mouse Hematopoietic Stem Cell Maintenance but Displays leukemia-Specific Gene Regulation.
Saha N; Ropa J; Chen L; Hu H; Mysliwski M; Friedman A; Maillard I; Muntean AG
Stem Cell Reports; 2019 May; 12(5):1069-1083. PubMed ID: 31031188
[TBL] [Abstract] [Full Text] [Related]
2. The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia.
Serio J; Ropa J; Chen W; Mysliwski M; Saha N; Chen L; Wang J; Miao H; Cierpicki T; Grembecka J; Muntean AG
Oncogene; 2018 Jan; 37(4):450-460. PubMed ID: 28945229
[TBL] [Abstract] [Full Text] [Related]
3. Transcriptional repression of tumor suppressor cdc73, encoding an RNA polymerase II interactor, by Wilms tumor 1 protein (WT1) promotes cell proliferation: implication for cancer therapeutics.
Rather MI; Swamy S; Gopinath KS; Kumar A
J Biol Chem; 2014 Jan; 289(2):968-76. PubMed ID: 24257751
[TBL] [Abstract] [Full Text] [Related]
4. MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.
Muntean AG; Chen W; Jones M; Granowicz EM; Maillard I; Hess JL
Blood; 2013 Sep; 122(11):1914-22. PubMed ID: 23900238
[TBL] [Abstract] [Full Text] [Related]