Terms: = Leukemia AND CDK6, MGC59692, 1021, Q00534, ENSG00000105810, PLSTIRE
286 results:
1. Systems Biology for Drug Target Discovery in Acute Myeloid leukemia.
Novikova S; Tolstova T; Kurbatov L; Farafonova T; Tikhonova O; Soloveva N; Rusanov A; Zgoda V
Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38731835
[TBL] [Abstract] [Full Text] [Related]
2. Narazaciclib, a novel multi-kinase inhibitor with potent activity against CSF1R, FLT3 and cdk6, shows strong anti-AML activity in defined preclinical models.
Yang T; Ke H; Liu J; An X; Xue J; Ning J; Hao F; Xiong L; Chen C; Wang Y; Zheng J; Gao B; Bao Z; Gong K; Zhang L; Zhang F; Guo S; Li QX
Sci Rep; 2024 Apr; 14(1):9032. PubMed ID: 38641704
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3. Long noncoding RNA LINC00675 drives malignancy in acute myeloid leukemia via the miR-6809 -cdk6 axis.
Long X; Jiang H; Liu Z; Liu J; Hu R
Pathol Res Pract; 2024 Mar; 255():155221. PubMed ID: 38422911
[TBL] [Abstract] [Full Text] [Related]
4. Transcriptome Analysis in Mexican Adults with Acute Lymphoblastic leukemia.
Cruz-Miranda GM; Olarte-Carrillo I; Bárcenas-López DA; Martínez-Tovar A; Ramírez-Bello J; Ramos-Peñafiel CO; García-Laguna AI; Cerón-Maldonado R; May-Hau D; Jiménez-Morales S
Int J Mol Sci; 2024 Feb; 25(3):. PubMed ID: 38339034
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5. Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM).
Mill CP; Fiskus WC; DiNardo CD; Reville P; Davis JA; Birdwell CE; Das K; Hou H; Takahashi K; Flores L; Ruan X; Su X; Loghavi S; Khoury JD; Bhalla KN
Blood Cancer J; 2024 Feb; 14(1):25. PubMed ID: 38316746
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6. 8-Hydroxydaidzein Induces Apoptosis and Inhibits AML-Associated Gene Expression in U-937 Cells: Potential Phytochemical for AML Treatment.
Wu PS; Wang CY; Hsu HJ; Yen JH; Wu MJ
Biomolecules; 2023 Oct; 13(11):. PubMed ID: 38002257
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7. Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation.
Yu S; Zhang Y; Yang J; Xu H; Lan S; Zhao B; Luo M; Ma X; Zhang H; Wang S; Shen H; Zhang Y; Xu Y; Li R
Eur J Med Chem; 2024 Jan; 263():115924. PubMed ID: 37992518
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8. cdk6: an attractive therapeutic target for T-ALL/LBL.
Li W; Hu JK; Hu MG
Expert Opin Ther Targets; 2023; 27(11):1087-1096. PubMed ID: 37975616
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9. Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia.
Aoki K; Hyuga M; Tarumoto Y; Nishibuchi G; Ueda A; Ochi Y; Sugino S; Mikami T; Kobushi H; Kato I; Akahane K; Inukai T; Takaori-Kondo A; Takita J; Ogawa S; Yusa K
Blood; 2024 Feb; 143(7):604-618. PubMed ID: 37922452
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10. Conferone, a coumarin from
Rafatpanah H; Golizadeh M; Mahdifar M; Mahdavi S; Iranshahi M; Rassouli FB
Int J Immunopathol Pharmacol; 2023; 37():3946320231197592. PubMed ID: 37688389
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11. Phase I Results of Bromodomain and Extra-Terminal Inhibitor PLX51107 in Combination with Azacitidine in Patients with Relapsed/Refractory Myeloid Malignancies.
Senapati J; Fiskus WC; Daver N; Wilson NR; Ravandi F; Garcia-Manero G; Kadia T; DiNardo CD; Jabbour E; Burger J; Short NJ; Alvarado Y; Jain N; Masarova L; Issa GC; Qiao W; Khoury JD; Pierce S; Miller D; Sasaki K; Konopleva M; Bhalla KN; Borthakur G; Pemmaraju N
Clin Cancer Res; 2023 Nov; 29(21):4352-4360. PubMed ID: 37585491
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12. Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis.
Bhasin SS; Thomas BE; Summers RJ; Sarkar D; Mumme H; Pilcher W; Emam M; Raikar SS; Park SI; Castellino SM; Graham DK; Bhasin MK; DeRyckere D
Sci Rep; 2023 Aug; 13(1):12556. PubMed ID: 37532715
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13. MicroRNA analysis of Natural Killer cell-derived exosomes: the microRNA let-7b-5p is enriched in exosomes and participates in their anti-tumor effects against pancreatic cancer cells.
Di Pace AL; Pelosi A; Fiore PF; Tumino N; Besi F; Quatrini L; Santopolo S; Vacca P; Moretta L
Oncoimmunology; 2023; 12(1):2221081. PubMed ID: 37304055
[TBL] [Abstract] [Full Text] [Related]
14. Dasatinib in combination with BMS-754807 induce synergistic cytotoxicity in lung cancer cells through inhibiting lung cancer cell growth, and inducing autophagy as well as cell cycle arrest at the G1 phase.
Zhang C; Zhao X; Wang Z; Gong T; Zhao H; Zhang D; Niu Y; Li X; Zhao X; Li G; Dong X; Zhang L; Liu C; Xu J; Yu B
Invest New Drugs; 2023 Jun; 41(3):438-452. PubMed ID: 37097369
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15. Palbociclib (PD 0332991) Interaction with Kinases. Theoretical and Comparative Molecular Docking Study.
Aceves-Hernández JM; Inés Nicolás Vázquez M; Luis Garza Rivera J; Espinoza Godínez A; Mateo Flores J; de Jesús Cruz Guzmán J; Castaño VM
Chem Biodivers; 2023 Mar; 20(3):e202200554. PubMed ID: 36799136
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16. NOTCH1 mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle G1/S transition and specific cyclin overexpression: Preclinical ground for targeted inhibition.
Carrillo-Tornel S; Chen-Liang TH; Zurdo M; Puiggros A; Gómez-Llonín A; García-Malo MD; Cuenca-Zamora EJ; Ortuño FJ; López AMH; Espinet B; Jerez A
Br J Haematol; 2023 May; 201(3):470-479. PubMed ID: 36573331
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17. EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment.
Masamoto Y; Chiba A; Mizuno H; Hino T; Hayashida H; Sato T; Bando M; Shirahige K; Kurokawa M
Blood Adv; 2023 Apr; 7(8):1577-1593. PubMed ID: 36269819
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18. Inhibition of DEK Enhances Doxorubicin-Induced Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic leukemia Cells.
Tian X; Zhu Z; Wang G; Xu J; Liang A; Zhang W
Dis Markers; 2022; 2022():9312971. PubMed ID: 35769815
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19. Population-based targeted RNA sequencing reveals novel disease-related gene fusions in pediatric and adult T-ALL.
Norvilas R; Batiuskaite R; Dirse V; Semaskeviciene R; Gineikiene E; Stoskus M; Vaitkeviciene G; Rascon J; Griskevicius L
Leuk Res; 2022 May; 116():106825. PubMed ID: 35339799
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20. Understanding the Molecular Mechanisms of Betel miRNAs on Human Health.
Manvar T; Mangukia N; Patel S; Rawal R
Microrna; 2022; 11(1):45-56. PubMed ID: 35307000
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