BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND CDK6, MGC59692, 1021, Q00534, ENSG00000105810, PLSTIRE AND Prognosis
24 results:

  • 1. Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis.
    Bhasin SS; Thomas BE; Summers RJ; Sarkar D; Mumme H; Pilcher W; Emam M; Raikar SS; Park SI; Castellino SM; Graham DK; Bhasin MK; DeRyckere D
    Sci Rep; 2023 Aug; 13(1):12556. PubMed ID: 37532715
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Targeted inhibitors and antibody immunotherapies: Novel therapies for paediatric leukaemia and lymphoma.
    Brivio E; Baruchel A; Beishuizen A; Bourquin JP; Brown PA; Cooper T; Gore L; Kolb EA; Locatelli F; Maude SL; Mussai FJ; Vormoor-Bürger B; Vormoor J; von Stackelberg A; Zwaan CM
    Eur J Cancer; 2022 Mar; 164():1-17. PubMed ID: 35121370
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. ZC3H15 Correlates with a Poor prognosis and Tumor Progression in Melanoma.
    Li Q; Hou J; Guo C; Zhang Y; Liu L; Hu H; Shi S; Ji Y; Guo L; Shi Y; Liu Y; Cui H
    Biomed Res Int; 2021; 2021():8305299. PubMed ID: 34988227
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Somatic homozygous loss of SH2B3, and a non-Robertsonian translocation t(15;21)(q25.3;q22.1) with NTRK3 rearrangement, in an adolescent with progenitor B-cell acute lymphoblastic leukemia with the iAMP21.
    Capela de Matos RR; Othman M; Ferreira GM; Monteso K; de Souza MT; Rouxinol M; Melo JB; Carreira IM; Abdelhay E; Liehr T; Ribeiro RC; Silva M
    Cancer Genet; 2022 Apr; 262-263():16-22. PubMed ID: 34974289
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Genome-wide CRISPR screen identifies cdk6 as a therapeutic target in adult T-cell leukemia/lymphoma.
    Ishio T; Kumar S; Shimono J; Daenthanasanmak A; Dubois S; Lin Y; Bryant B; Petrus MN; Bachy E; Huang DW; Yang Y; Green PL; Hasegawa H; Maeda M; Goto H; Endo T; Yokota T; Hatanaka KC; Hatanaka Y; Tanaka S; Matsuno Y; Yang Y; Hashino S; Teshima T; Waldmann TA; Staudt LM; Nakagawa M
    Blood; 2022 Mar; 139(10):1541-1556. PubMed ID: 34818414
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Targeting the cdk6 Dependence of Ph+ Acute Lymphoblastic leukemia.
    Porazzi P; De Dominici M; Salvino J; Calabretta B
    Genes (Basel); 2021 Aug; 12(9):. PubMed ID: 34573335
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Dual PI3K/mTOR inhibitor NVP‑BEZ235 decreases the proliferation of doxorubicin‑resistant K562 cells.
    Li J; Wang X; Ma C; Xu S; Xu M; Yang J; Wang R; Xue L
    Mol Med Rep; 2021 Apr; 23(4):. PubMed ID: 34223631
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. cdk6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.
    Schmoellerl J; Barbosa IAM; Eder T; Brandstoetter T; Schmidt L; Maurer B; Troester S; Pham HTT; Sagarajit M; Ebner J; Manhart G; Aslan E; Terlecki-Zaniewicz S; Van der Veen C; Hoermann G; Duployez N; Petit A; Lapillonne H; Puissant A; Itzykson R; Moriggl R; Heuser M; Meisel R; Valent P; Sexl V; Zuber J; Grebien F
    Blood; 2020 Jul; 136(4):387-400. PubMed ID: 32344427
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Atypical 3q26/MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia.
    Ottema S; Mulet-Lazaro R; Beverloo HB; Erpelinck C; van Herk S; van der Helm R; Havermans M; Grob T; Valk PJM; Bindels E; Haferlach T; Haferlach C; Smeenk L; Delwel R
    Blood; 2020 Jul; 136(2):224-234. PubMed ID: 32219447
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome.
    Wang H; Zhang TT; Jin S; Liu H; Zhang X; Ruan CG; Wu DP; Han Y; Wang XQ
    Clin Epigenetics; 2017; 9():91. PubMed ID: 28861128
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The role of CDKN2A/B deletions in pediatric acute lymphoblastic leukemia.
    Carrasco Salas P; Fernández L; Vela M; Bueno D; González B; Valentín J; Lapunzina P; Pérez-Martínez A
    Pediatr Hematol Oncol; 2016; 33(7-8):415-422. PubMed ID: 27960642
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Chronic myelogenous leukemia with acquired t(11;14)(q13;q32) CCND1-IGH: A case report and literature review.
    Manda-Mapalo MT; Khalili P; Quintana D; Rabinowitz I; Zhang QY
    Cancer Genet; 2016 Oct; 209(10):481-485. PubMed ID: 27810077
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by cdk6.
    Uras IZ; Walter GJ; Scheicher R; Bellutti F; Prchal-Murphy M; Tigan AS; Valent P; Heidel FH; Kubicek S; Scholl C; Fröhling S; Sexl V
    Blood; 2016 Jun; 127(23):2890-902. PubMed ID: 27099147
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation.
    Palanichamy JK; Tran TM; Howard JM; Contreras JR; Fernando TR; Sterne-Weiler T; Katzman S; Toloue M; Yan W; Basso G; Pigazzi M; Sanford JR; Rao DS
    J Clin Invest; 2016 Apr; 126(4):1495-511. PubMed ID: 26974154
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Overexpression of ATP1B1 predicts an adverse prognosis in cytogenetically normal acute myeloid leukemia.
    Shi JL; Fu L; Ang Q; Wang GJ; Zhu J; Wang WD
    Oncotarget; 2016 Jan; 7(3):2585-95. PubMed ID: 26506237
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Leukemogenesis as a new approach to investigate the correlation between up regulated gene 4/upregulator of cell proliferation (URG4/URGCP) and signal transduction genes in leukemia.
    Dodurga Y; Oymak Y; Gündüz C; Satıroglu-Tufan NL; Vergin C; Cetingül N; Biray Avci C; Topçuoğlu N
    Mol Biol Rep; 2013 Apr; 40(4):3043-8. PubMed ID: 23266667
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Three novel cytogenetically cryptic EVI1 rearrangements associated with increased EVI1 expression and poor prognosis identified in 27 acute myeloid leukemia cases.
    Haferlach C; Bacher U; Grossmann V; Schindela S; Zenger M; Kohlmann A; Kern W; Haferlach T; Schnittger S
    Genes Chromosomes Cancer; 2012 Dec; 51(12):1079-85. PubMed ID: 22887804
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates cdk6 expression and confers a poor prognosis in acute lymphoblastic leukemia.
    Agirre X; Vilas-Zornoza A; Jiménez-Velasco A; Martin-Subero JI; Cordeu L; Gárate L; San José-Eneriz E; Abizanda G; Rodríguez-Otero P; Fortes P; Rifón J; Bandrés E; Calasanz MJ; Martín V; Heiniger A; Torres A; Siebert R; Román-Gomez J; Prósper F
    Cancer Res; 2009 May; 69(10):4443-53. PubMed ID: 19435910
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosis.
    Cavazzini F; Hernandez JA; Gozzetti A; Russo Rossi A; De Angeli C; Tiseo R; Bardi A; Tammiso E; Crupi R; Lenoci MP; Forconi F; Lauria F; Marasca R; Maffei R; Torelli G; Gonzalez M; Martin-Jimenez P; Maria Hernandez J; Rigolin GM; Cuneo A
    Br J Haematol; 2008 Aug; 142(4):529-37. PubMed ID: 18547320
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Identification of differentially expressed genes in tobacco chewing-mediated oral cancer by differential display-polymerase chain reaction.
    Nagpal JK; Das BR
    Eur J Clin Invest; 2007 Aug; 37(8):658-64. PubMed ID: 17635577
    [TBL] [Abstract] [Full Text] [Related]  


    [Next]

    of 2.