BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND CDKN2A, CDK4I, 1029, ENSG00000147889, P42771, p14, CMM2, ARF, TP16, p16, MTS1, p19, p16INK4a, INK4a, CDKN2, p16INK4, p14ARF, MLM, INK4 AND Clinical Outcome
27 results:

  • 1. Aberrant hydroxymethylation in promoter CpG regions of genes related to the cell cycle and apoptosis characterizes advanced chronic myeloid leukemia disease, poor imatinib respondents and poor survival.
    Guru SA; Sumi MP; Mir R; Beg MMA; Koner BC; Saxena A
    BMC Cancer; 2022 Apr; 22(1):405. PubMed ID: 35421941
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Frequency and Correlation of Common Genes Copy Number Alterations in Childhood Acute Lymphoblastic leukemia with Prognosis.
    Hosein Pour Feizi A; Zeinali S; Toporski J; Sheervalilou R; Mehranfar S
    Asian Pac J Cancer Prev; 2020 Dec; 21(12):3493-3500. PubMed ID: 33369444
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Prognostic gene alterations and clonal changes in childhood B-ALL.
    Erbilgin Y; Firtina S; Mercan S; Hatirnaz Ng O; Karaman S; Tasar O; Karakas Z; Celkan TT; Zengin E; Sarper N; Yildirmak ZY; Sisko S; Ozbek U; Sayitoglu M
    Leuk Res; 2019 Aug; 83():106159. PubMed ID: 31228652
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Copy number alterations in B-cell development genes, drug resistance, and clinical outcome in pediatric B-cell precursor acute lymphoblastic leukemia.
    Steeghs EMP; Boer JM; Hoogkamer AQ; Boeree A; de Haas V; de Groot-Kruseman HA; Horstmann MA; Escherich G; Pieters R; den Boer ML
    Sci Rep; 2019 Mar; 9(1):4634. PubMed ID: 30874617
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.
    Bastian L; Schroeder MP; Eckert C; Schlee C; Tanchez JO; Kämpf S; Wagner DL; Schulze V; Isaakidis K; Lázaro-Navarro J; Hänzelmann S; James AR; Ekici A; Burmeister T; Schwartz S; Schrappe M; Horstmann M; Vosberg S; Krebs S; Blum H; Hecht J; Greif PA; Rieger MA; Brüggemann M; Gökbuget N; Neumann M; Baldus CD
    Leukemia; 2019 Aug; 33(8):1895-1909. PubMed ID: 30842609
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Non-leukemic pediatric mixed phenotype acute leukemia/lymphoma: Genomic characterization and clinical outcome in a prospective trial for pediatric lymphoblastic lymphoma.
    Martin-Guerrero I; Salaverria I; Burkhardt B; Chassagne-Clement C; Szczepanowski M; Bens S; Klapper W; Zimmermann M; Kabickova E; Bertrand Y; Reiter A; Siebert R; Oschlies I
    Genes Chromosomes Cancer; 2019 Jun; 58(6):365-372. PubMed ID: 30578714
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Senescence-associated reprogramming promotes cancer stemness.
    Milanovic M; Fan DNY; Belenki D; Däbritz JHM; Zhao Z; Yu Y; Dörr JR; Dimitrova L; Lenze D; Monteiro Barbosa IA; Mendoza-Parra MA; Kanashova T; Metzner M; Pardon K; Reimann M; Trumpp A; Dörken B; Zuber J; Gronemeyer H; Hummel M; Dittmar G; Lee S; Schmitt CA
    Nature; 2018 Jan; 553(7686):96-100. PubMed ID: 29258294
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide polymorphism analysis.
    Bullinger L; Krönke J; Schön C; Radtke I; Urlbauer K; Botzenhardt U; Gaidzik V; Carió A; Senger C; Schlenk RF; Downing JR; Holzmann K; Döhner K; Döhner H
    Leukemia; 2010 Feb; 24(2):438-49. PubMed ID: 20016533
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Nucleophosmin gene mutations in acute myeloid leukemia.
    Chen W; Rassidakis GZ; Medeiros LJ
    Arch Pathol Lab Med; 2006 Nov; 130(11):1687-92. PubMed ID: 17076533
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Methylation of ink4 and CIP/KIP families of cyclin-dependent kinase inhibitor in chronic lymphocytic leukaemia in Chinese patients.
    Chim CS; Fung TK; Wong KF; Lau JS; Law M; Liang R
    J Clin Pathol; 2006 Sep; 59(9):921-6. PubMed ID: 16565223
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Children and adults with acute lymphoblastic leukaemia have similar gene expression profiles.
    Kuchinskaya E; Heyman M; Grandér D; Linderholm M; Söderhäll S; Zaritskey A; Nordgren A; Porwit-Macdonald A; Zueva E; Pawitan Y; Corcoran M; Nordenskjöld M; Blennow E
    Eur J Haematol; 2005 Jun; 74(6):466-80. PubMed ID: 15876250
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome.
    Rubio-Moscardo F; Climent J; Siebert R; Piris MA; Martín-Subero JI; Nieländer I; Garcia-Conde J; Dyer MJ; Terol MJ; Pinkel D; Martinez-Climent JA
    Blood; 2005 Jun; 105(11):4445-54. PubMed ID: 15718413
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Inactivation of p16 gene in leukemia.
    Wenming C; Jiazhi Z; Shuzhen T; Bai X; Jingzhong L
    Chin Med Sci J; 1999 Dec; 14(4):206-10. PubMed ID: 12894892
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Partial deletions of long arm of chromosome 6: biologic and clinical implications in adult acute lymphoblastic leukemia.
    Mancini M; Vegna ML; Castoldi GL; Mecucci C; Spirito F; Elia L; Tafuri A; Annino L; Pane F; Rege-Cambrin G; Gottardi M; Leoni P; Gallo E; Camera A; Luciano L; Specchia G; Torelli G; Sborgia M; Gabbas A; Tedeschi A; Della Starza I; Cascavilla N; Di Raimondo F; Mandelli F; Foà R
    Leukemia; 2002 Oct; 16(10):2055-61. PubMed ID: 12357357
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. LAF4, an AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia.
    von Bergh AR; Beverloo HB; Rombout P; van Wering ER; van Weel MH; Beverstock GC; Kluin PM; Slater RM; Schuuring E
    Genes Chromosomes Cancer; 2002 Sep; 35(1):92-6. PubMed ID: 12203795
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Loss of heterozygosity of p16 correlates with minimal residual disease at the end of the induction therapy in non-high risk childhood B-cell precursor acute lymphoblastic leukemia.
    Tutor O; Díaz MA; Ramírez M; Algara P; Madero L; Martínez P
    Leuk Res; 2002 Sep; 26(9):817-20. PubMed ID: 12127556
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The absence of the p15ink4B gene alterations in adult patients with precursor B-cell acute lymphoblastic leukaemia is a favourable prognostic factor.
    Hoshino K; Asou N; Okubo T; Suzushima H; Kiyokawa T; Kawano F; Mitsuya H
    Br J Haematol; 2002 Jun; 117(3):531-40. PubMed ID: 12028019
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Sensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3.
    Niitsu N; Hayashi Y; Sugita K; Honma Y
    Br J Haematol; 2001 Feb; 112(2):315-26. PubMed ID: 11167824
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16ink4a.
    Møller MB; Kania PW; Ino Y; Gerdes AM; Nielsen O; Louis DN; Skjødt K; Pedersen NT
    Leukemia; 2000 May; 14(5):898-904. PubMed ID: 10803523
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Cell cycle regulatory gene abnormalities are important determinants of leukemogenesis and disease biology in adult acute lymphoblastic leukemia.
    Stock W; Tsai T; Golden C; Rankin C; Sher D; Slovak ML; Pallavicini MG; Radich JP; Boldt DH
    Blood; 2000 Apr; 95(7):2364-71. PubMed ID: 10733508
    [TBL] [Abstract] [Full Text] [Related]  


    [Next]

    of 2.