Terms: = Leukemia AND CTCF, P49711, 10664, ENSG00000102974 AND Treatment
24 results:
1. An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions.
Radzisheuskaya A; Peña-Rømer I; Lorenzini E; Koche R; Zhan Y; Shliaha PV; Cooper AJ; Fan Z; Shlyueva D; Johansen JV; Hendrickson RC; Helin K
EMBO J; 2023 Dec; 42(24):e114221. PubMed ID: 37987160
[TBL] [Abstract] [Full Text] [Related]
2. Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.
Gray ZH; Chakraborty D; Duttweiler RR; Alekbaeva GD; Murphy SE; Chetal K; Ji F; Ferman BI; Honer MA; Wang Z; Myers C; Sun R; Kaniskan HÜ; Toma MM; Bondarenko EA; Santoro JN; Miranda C; Dillingham ME; Tang R; Gozani O; Jin J; Skorski T; Duy C; Lee H; Sadreyev RI; Whetstine JR
Cell; 2023 Oct; 186(21):4528-4545.e18. PubMed ID: 37788669
[TBL] [Abstract] [Full Text] [Related]
3. Isocitrate dehydrogenase 1 mutation drives leukemogenesis by PDGFRA activation due to insulator disruption in acute myeloid leukemia (AML).
Steinhäuser S; Silva P; Lenk L; Beder T; Hartmann A; Hänzelmann S; Fransecky L; Neumann M; Bastian L; Lipinski S; Richter K; Bultmann M; Hübner E; Xia S; Röllig C; Vogiatzi F; Schewe DM; Yumiceba V; Schultz K; Spielmann M; Baldus CD
Leukemia; 2023 Jan; 37(1):134-142. PubMed ID: 36411356
[TBL] [Abstract] [Full Text] [Related]
4. Subtype-specific 3D genome alteration in acute myeloid leukaemia.
Xu J; Song F; Lyu H; Kobayashi M; Zhang B; Zhao Z; Hou Y; Wang X; Luan Y; Jia B; Stasiak L; Wong JH; Wang Q; Jin Q; Jin Q; Fu Y; Yang H; Hardison RC; Dovat S; Platanias LC; Diao Y; Yang Y; Yamada T; Viny AD; Levine RL; Claxton D; Broach JR; Zheng H; Yue F
Nature; 2022 Nov; 611(7935):387-398. PubMed ID: 36289338
[TBL] [Abstract] [Full Text] [Related]
5. Tumour-derived small extracellular vesicles suppress CD8+ T cell immune function by inhibiting SLC6A8-mediated creatine import in NPM1-mutated acute myeloid leukaemia.
Peng M; Ren J; Jing Y; Jiang X; Xiao Q; Huang J; Tao Y; Lei L; Wang X; Yang Z; Yang Z; Zhan Q; Lin C; Jin G; Zhang X; Zhang L
J Extracell Vesicles; 2021 Nov; 10(13):e12168. PubMed ID: 34807526
[TBL] [Abstract] [Full Text] [Related]
6. The clinical outcomes and genomic landscapes of acute lymphoblastic leukemia patients with E2A-PBX1: A 10-year retrospective study.
Zhou B; Chu X; Tian H; Liu T; Liu H; Gao W; Chen S; Hu S; Wu D; Xu Y
Am J Hematol; 2021 Nov; 96(11):1461-1471. PubMed ID: 34406703
[TBL] [Abstract] [Full Text] [Related]
7. Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites.
Atkin ND; Raimer HM; Wang Z; Zang C; Wang YH
Genes Chromosomes Cancer; 2021 Dec; 60(12):808-821. PubMed ID: 34405474
[TBL] [Abstract] [Full Text] [Related]
8. Disruption of ctcf Boundary at HOXA Locus Promote BET Inhibitors' Therapeutic Sensitivity in Acute Myeloid leukemia.
Zha J; Lai Q; Deng M; Shi P; Zhao H; Chen Q; Wu H; Xu B
Stem Cell Rev Rep; 2020 Dec; 16(6):1280-1291. PubMed ID: 33057942
[TBL] [Abstract] [Full Text] [Related]
9. Determinants and role of chromatin organization in acute leukemia.
Fang C; Rao S; Crispino JD; Ntziachristos P
Leukemia; 2020 Oct; 34(10):2561-2575. PubMed ID: 32690881
[TBL] [Abstract] [Full Text] [Related]
10. ctcf-mediated genome organization and leukemogenesis.
Qiu Y; Huang S
Leukemia; 2020 Sep; 34(9):2295-2304. PubMed ID: 32518417
[TBL] [Abstract] [Full Text] [Related]
11. Characterization of chromosome organization in the differentiation of acute myeloid leukemia cells by all-trans retinoic acid.
Hu Y; Zhao H; Zhao Y; Zheng J; Guo Y; Ma J
Life Sci; 2020 May; 249():117479. PubMed ID: 32119959
[TBL] [Abstract] [Full Text] [Related]
12. The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data.
Fernández-Navarro P; López-Nieva P; Piñeiro-Yañez E; Carreño-Tarragona G; Martinez-López J; Sánchez Pérez R; Aroca Á; Al-Shahrour F; Cobos-Fernández MÁ; Fernández-Piqueras J
BMC Cancer; 2019 Oct; 19(1):1005. PubMed ID: 31655559
[TBL] [Abstract] [Full Text] [Related]
13. Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility.
Atkin ND; Raimer HM; Wang YH
Genes (Basel); 2019 Oct; 10(10):. PubMed ID: 31614754
[TBL] [Abstract] [Full Text] [Related]
14. Genomic and epigenomic predictors of response to guadecitabine in relapsed/refractory acute myelogenous leukemia.
Chung W; Kelly AD; Kropf P; Fung H; Jelinek J; Su XY; Roboz GJ; Kantarjian HM; Azab M; Issa JJ
Clin Epigenetics; 2019 Jul; 11(1):106. PubMed ID: 31331399
[TBL] [Abstract] [Full Text] [Related]
15. Increased methylation upstream of the MEG3 promotor is observed in acute myeloid leukemia patients with better overall survival.
Sellers ZP; Bolkun L; Kloczko J; Wojtaszewska ML; Lewandowski K; Moniuszko M; Ratajczak MZ; Schneider G
Clin Epigenetics; 2019 Mar; 11(1):50. PubMed ID: 30876483
[TBL] [Abstract] [Full Text] [Related]
16. Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic leukemia.
Jing D; Huang Y; Liu X; Sia KCS; Zhang JC; Tai X; Wang M; Toscan CE; McCalmont H; Evans K; Mayoh C; Poulos RC; Span M; Mi J; Zhang C; Wong JWH; Beck D; Pimanda JE; Lock RB
Cancer Cell; 2018 Dec; 34(6):906-921.e8. PubMed ID: 30537513
[TBL] [Abstract] [Full Text] [Related]
17. PARP1 Stabilizes ctcf Binding and Chromatin Structure To Maintain Epstein-Barr Virus Latency Type.
Lupey-Green LN; Caruso LB; Madzo J; Martin KA; Tan Y; Hulse M; Tempera I
J Virol; 2018 Sep; 92(18):. PubMed ID: 29976663
[TBL] [Abstract] [Full Text] [Related]
18. ctcf boundary remodels chromatin domain and drives aberrant
Luo H; Wang F; Zha J; Li H; Yan B; Du Q; Yang F; Sobh A; Vulpe C; Drusbosky L; Cogle C; Chepelev I; Xu B; Nimer SD; Licht J; Qiu Y; Chen B; Xu M; Huang S
Blood; 2018 Aug; 132(8):837-848. PubMed ID: 29760161
[No Abstract] [Full Text] [Related]
19. Mutational Landscape of Pediatric Acute Lymphoblastic leukemia.
Ding LW; Sun QY; Tan KT; Chien W; Mayakonda A; Yeoh AEJ; Kawamata N; Nagata Y; Xiao JF; Loh XY; Lin DC; Garg M; Jiang YY; Xu L; Lim SL; Liu LZ; Madan V; Sanada M; Fernández LT; Hema Preethi SS; Lill M; Kantarjian HM; Kornblau SM; Miyano S; Liang DC; Ogawa S; Shih LY; Yang H; Koeffler HP
Cancer Res; 2017 Jan; 77(2):390-400. PubMed ID: 27872090
[TBL] [Abstract] [Full Text] [Related]
20. Molecular and Cellular Mechanisms of Myelodysplastic Syndrome: Implications on Targeted Therapy.
Gill H; Leung AY; Kwong YL
Int J Mol Sci; 2016 Mar; 17(4):440. PubMed ID: 27023522
[TBL] [Abstract] [Full Text] [Related]
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