BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND CUX1, ENSG00000160967, P39880, p75, p200, p110, p100, Nbla10317, CUX, COY1, CDP, CASP, 1523 AND Prognosis
14 results:

  • 1. Cut-like homeobox 1 (cux1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia.
    Supper E; Rudat S; Iyer V; Droop A; Wong K; Spinella JF; Thomas P; Sauvageau G; Adams DJ; Wong CC
    Nat Commun; 2021 Apr; 12(1):2482. PubMed ID: 33931647
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. LEDGF/p75-mediated chemoresistance of mixed-lineage leukemia involves cell survival pathways and super enhancer activators.
    Canella A; Van Belle S; Brouns T; Nigita G; Carlon MS; Christ F; Debyser Z
    Cancer Gene Ther; 2022 Feb; 29(2):133-140. PubMed ID: 33795806
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. [Genetic defects of chromosome 5q and 7q in myeloid neoplasms].
    Hosono N
    Rinsho Ketsueki; 2019; 60(7):800-809. PubMed ID: 31391370
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. [Mutational Profiling of Pediatric Myeloid leukemia Subtypes without Clinically Significant Chromosomal Aberrations].
    Ghukasyan LG; Krasnov GS; Muravenko OV; Baidun LV; Ibragimova SZ; Nasedkina TV
    Mol Biol (Mosk); 2019; 53(3):402-410. PubMed ID: 31184605
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Next-generation sequencing with a 54-gene panel identified unique mutational profile and prognostic markers in Chinese patients with myelofibrosis.
    Gill H; Ip HW; Yim R; Tang WF; Pang HH; Lee P; Leung GMK; Li J; Tang K; So JCC; Leung RYY; Li J; Panagioutou G; Lam CCK; Kwong YL
    Ann Hematol; 2019 Apr; 98(4):869-879. PubMed ID: 30515541
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Protein-protein and protein-chromatin interactions of LEDGF/p75 as novel drug targets.
    Blokken J; De Rijck J; Christ F; Debyser Z
    Drug Discov Today Technol; 2017 Jun; 24():25-31. PubMed ID: 29233296
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia.
    Evangelisti C; Cappellini A; Oliveira M; Fragoso R; Barata JT; Bertaina A; Locatelli F; Simioni C; Neri LM; Chiarini F; Lonetti A; Buontempo F; Orsini E; Pession A; Manzoli L; Martelli AM; Evangelisti C
    J Cell Physiol; 2018 Mar; 233(3):1796-1811. PubMed ID: 28777460
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Frequency of rare BCR-ABL1 fusion transcripts in chronic myeloid leukemia patients.
    Arun AK; Senthamizhselvi A; Mani S; Vinodhini K; Janet NB; Lakshmi KM; Abraham A; George B; Srivastava A; Srivastava VM; Mathews V; Balasubramanian P
    Int J Lab Hematol; 2017 Jun; 39(3):235-242. PubMed ID: 28035733
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Idelalisib: First-in-Class PI3K Delta Inhibitor for the Treatment of Chronic Lymphocytic leukemia, Small Lymphocytic leukemia, and Follicular Lymphoma.
    Yang Q; Modi P; Newcomb T; Quéva C; Gandhi V
    Clin Cancer Res; 2015 Apr; 21(7):1537-42. PubMed ID: 25670221
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia.
    Cermáková K; Tesina P; Demeulemeester J; El Ashkar S; Méreau H; Schwaller J; Rezáčová P; Veverka V; De Rijck J
    Cancer Res; 2014 Sep; 74(18):5139-51. PubMed ID: 25082813
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. cux1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
    McNerney ME; Brown CD; Wang X; Bartom ET; Karmakar S; Bandlamudi C; Yu S; Ko J; Sandall BP; Stricker T; Anastasi J; Grossman RL; Cunningham JM; Le Beau MM; White KP
    Blood; 2013 Feb; 121(6):975-83. PubMed ID: 23212519
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Two distinct gene expression signatures in pediatric acute lymphoblastic leukemia with MLL rearrangements.
    Tsutsumi S; Taketani T; Nishimura K; Ge X; Taki T; Sugita K; Ishii E; Hanada R; Ohki M; Aburatani H; Hayashi Y
    Cancer Res; 2003 Aug; 63(16):4882-7. PubMed ID: 12941810
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Pilot study of recombinant human soluble tumor necrosis factor (TNF) receptor (p75) fusion protein (TNFR:Fc; Enbrel) in patients with refractory multiple myeloma: increase in plasma TNF alpha levels during treatment.
    Tsimberidou AM; Waddelow T; Kantarjian HM; Albitar M; Giles FJ
    Leuk Res; 2003 May; 27(5):375-80. PubMed ID: 12620287
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Aberrant expression of caspase cascade regulatory genes in adult T-cell leukaemia: survivin is an important determinant for prognosis.
    Kamihira S; Yamada Y; Hirakata Y; Tomonaga M; Sugahara K; Hayashi T; Dateki N; Harasawa H; Nakayama K
    Br J Haematol; 2001 Jul; 114(1):63-9. PubMed ID: 11472346
    [TBL] [Abstract] [Full Text] [Related]  


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