Terms: = Leukemia AND EP300, ENSG00000100393, 2033, RP1-85F18_1, p300 AND Treatment
82 results:
1. Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong
Hu J; Xu H; Wu T; Zhang C; Shen H; Dong R; Hu Q; Xiang Q; Chai S; Luo G; Chen X; Huang Y; Zhao X; Peng C; Wu X; Lin B; Zhang Y; Xu Y
J Med Chem; 2024 May; 67(9):6952-6986. PubMed ID: 38649304
[TBL] [Abstract] [Full Text] [Related]
2. Synergistic cytotoxicity of decitabine and YM155 in leukemia cells through upregulation of SLC35F2 and suppression of MCL1 and survivin expression.
Chiou JT; Chang LS
Apoptosis; 2024 Apr; 29(3-4):503-520. PubMed ID: 38066391
[TBL] [Abstract] [Full Text] [Related]
3. Therapeutic targeting of ep300/CBP by bromodomain inhibition in hematologic malignancies.
Nicosia L; Spencer GJ; Brooks N; Amaral FMR; Basma NJ; Chadwick JA; Revell B; Wingelhofer B; Maiques-Diaz A; Sinclair O; Camera F; Ciceri F; Wiseman DH; Pegg N; West W; Knurowski T; Frese K; Clegg K; Campbell VL; Cavet J; Copland M; Searle E; Somervaille TCP
Cancer Cell; 2023 Dec; 41(12):2136-2153.e13. PubMed ID: 37995682
[TBL] [Abstract] [Full Text] [Related]
4. Discovery of Exceptionally Potent, Selective, and Efficacious PROTAC Degraders of CBP and p300 Proteins.
Thomas JE; Wang M; Jiang W; Wang M; Wang L; Wen B; Sun D; Wang S
J Med Chem; 2023 Jun; 66(12):8178-8199. PubMed ID: 37276143
[TBL] [Abstract] [Full Text] [Related]
5. Efficient diagnosis of hematologic malignancies using bone marrow microscopic images: A method based on MultiPathGAN and MobileViTv2.
Yang G; Qin Z; Mu J; Mao H; Mao H; Han M
Comput Methods Programs Biomed; 2023 Jul; 237():107583. PubMed ID: 37167882
[TBL] [Abstract] [Full Text] [Related]
6. Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1.
Fiskus W; Mill CP; Birdwell C; Davis JA; Das K; Boettcher S; Kadia TM; DiNardo CD; Takahashi K; Loghavi S; Soth MJ; Heffernan T; McGeehan GM; Ruan X; Su X; Vakoc CR; Daver N; Bhalla KN
Blood Cancer J; 2023 Apr; 13(1):53. PubMed ID: 37055414
[TBL] [Abstract] [Full Text] [Related]
7. Targeted therapy using larotrectinib and venetoclax for the relapsed/refractory T-cell acute lymphoblastic leukemia harboring a cryptic ETV6-NTRK3 fusion.
Zhou K; Gong D; He C; Xiao M; Zhang M; Huang W
Mol Carcinog; 2023 Jul; 62(7):899-906. PubMed ID: 37036164
[TBL] [Abstract] [Full Text] [Related]
8. Zinc finger protein 384 (
Sudutan T; Erbilgin Y; Hatirnaz Ng O; Karaman S; Karakas Z; Kucukcankurt F; Celkan T; Timur C; Ozdemir GN; Hacısalihoglu S; Gelen SA; Sayitoğlu M
Leuk Lymphoma; 2022 Dec; 63(12):2931-2939. PubMed ID: 35921545
[TBL] [Abstract] [Full Text] [Related]
9. Phase I study of alvocidib plus cytarabine/mitoxantrone or cytarabine/daunorubicin for acute myeloid leukemia in Japan.
Ikezoe T; Ando K; Onozawa M; Yamane T; Hosono N; Morita Y; Kiguchi T; Iwasaki H; Miyamoto T; Matsubara K; Sugimoto S; Miyazaki Y; Kizaki M; Akashi K
Cancer Sci; 2022 Dec; 113(12):4258-4266. PubMed ID: 35689544
[TBL] [Abstract] [Full Text] [Related]
10. Src-Family Protein Kinase Inhibitors Suppress MYB Activity in a p300-Dependent Manner.
Biyanee A; Yusenko MV; Klempnauer KH
Cells; 2022 Mar; 11(7):. PubMed ID: 35406726
[TBL] [Abstract] [Full Text] [Related]
11. Inhibition of CBP synergizes with the RNA-dependent mechanisms of Azacitidine by limiting protein synthesis.
Diesch J; Le Pannérer MM; Winkler R; Casquero R; Muhar M; van der Garde M; Maher M; Herráez CM; Bech-Serra JJ; Fellner M; Rathert P; Brooks N; Zamora L; Gentilella A; de la Torre C; Zuber J; Götze KS; Buschbeck M
Nat Commun; 2021 Oct; 12(1):6060. PubMed ID: 34663789
[TBL] [Abstract] [Full Text] [Related]
12. ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells.
Fishman H; Madiwale S; Geron I; Bari V; Van Loocke W; Kirschenbaum Y; Ganmore I; Kugler E; Rein-Gil A; Friedlander G; Schiby G; Birger Y; Strehl S; Soulier J; Knoechel B; Ferrando A; Noy-Lotan S; Nagler A; Mulloy JC; Van Vlierberghe P; Izraeli S
Blood; 2022 Jan; 139(3):399-412. PubMed ID: 34624096
[TBL] [Abstract] [Full Text] [Related]
13. Carboxyl group-modified α-lactalbumin induces TNF-α-mediated apoptosis in leukemia and breast cancer cells through the NOX4/p38 MAPK/PP2A axis.
Chiou JT; Shi YJ; Lee YC; Wang LJ; Chen YJ; Chang LS
Int J Biol Macromol; 2021 Sep; 187():513-527. PubMed ID: 34310992
[TBL] [Abstract] [Full Text] [Related]
14. Fms-like tyrosine kinase 3-internal tandem duplications epigenetically activates checkpoint kinase 1 in acute myeloid leukemia cells.
Zhang Y; Yuan L
Sci Rep; 2021 Jun; 11(1):13236. PubMed ID: 34168220
[TBL] [Abstract] [Full Text] [Related]
15. Bromodomain protein BRD4 is an epigenetic activator of B7-H6 expression in acute myeloid leukemia.
Baragaño Raneros A; Rodriguez RM; Bernardo Flórez A; Palomo P; Colado E; Minguela A; Suárez Álvarez B; López-Larrea C
Oncoimmunology; 2021 Mar; 10(1):1897294. PubMed ID: 33796404
[TBL] [Abstract] [Full Text] [Related]
16. A Multi-Institutional Cohort of Therapy-Associated Polyposis in Childhood and Young Adulthood Cancer Survivors.
Biller LH; Ukaegbu C; Dhingra TG; Burke CA; Chertock Y; Chittenden A; Church JM; Koeppe ES; Leach BH; Levinson E; Lim RM; Lutz M; Salo-Mullen E; Sheikh R; Idos G; Kastrinos F; Stoffel E; Weiss JM; Hall MJ; Kalady MF; Stadler ZK; Syngal S; Yurgelun MB
Cancer Prev Res (Phila); 2020 Mar; 13(3):291-298. PubMed ID: 32051178
[TBL] [Abstract] [Full Text] [Related]
17. Second primary cancers in people who had cancer as children: an Australian Childhood Cancer Registry population-based study.
Youlden DR; Baade PD; Green AC; Valery PC; Moore AS; Aitken JF
Med J Aust; 2020 Feb; 212(3):121-125. PubMed ID: 31743457
[TBL] [Abstract] [Full Text] [Related]
18. m7FLIPI and targeted sequencing in high-risk follicular lymphoma.
Sorigue M; Oliveira A; Mercadal S; Tapia G; Climent F; Perez-Roca L; Lorences I; Domingo-Domenech E; Cabezon M; Navarro JT; Gonzalez-Barca E; Zamora L; Ribera JM; Sureda A; Armengol MP; Sancho JM
Hematol Oncol; 2019 Dec; 37(5):564-568. PubMed ID: 31475375
[TBL] [Abstract] [Full Text] [Related]
19. Leprosy drug clofazimine activates peroxisome proliferator-activated receptor-γ and synergizes with imatinib to inhibit chronic myeloid leukemia cells.
Kumar H; Chattopadhyay S; Das N; Shree S; Patel D; Mohapatra J; Gurjar A; Kushwaha S; Singh AK; Dubey S; Lata K; Kushwaha R; Mohammed R; Dastidar KG; Yadav N; Vishwakarma AL; Gayen JR; Bandyopadhyay S; Chatterjee A; Jain MR; Tripathi AK; Trivedi AK; Chattopadhyay N; Ramachandran R; Sanyal S
Haematologica; 2020 Apr; 105(4):971-986. PubMed ID: 31371410
[TBL] [Abstract] [Full Text] [Related]
20. CVID-Associated Tumors: Czech Nationwide Study Focused on Epidemiology, Immunology, and Genetic Background in a Cohort of Patients With CVID.
Kralickova P; Milota T; Litzman J; Malkusova I; Jilek D; Petanova J; Vydlakova J; Zimulova A; Fronkova E; Svaton M; Kanderova V; Bloomfield M; Parackova Z; Klocperk A; Haviger J; Kalina T; Sediva A
Front Immunol; 2018; 9():3135. PubMed ID: 30723478
[No Abstract] [Full Text] [Related]
[Next]
