BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND EZH2, ENX-1, 2146, ENSG00000106462, Q15910, MGC9169 AND Treatment
136 results:

  • 1. Construction and experimental validation of a novel ferroptosis-related gene signature for myelodysplastic syndromes.
    Zhu Y; He J; Wei R; Liu J
    Immun Inflamm Dis; 2024 Apr; 12(4):e1221. PubMed ID: 38578040
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Mechanisms of action and resistance in histone methylation-targeted therapy.
    Yamagishi M; Kuze Y; Kobayashi S; Nakashima M; Morishima S; Kawamata T; Makiyama J; Suzuki K; Seki M; Abe K; Imamura K; Watanabe E; Tsuchiya K; Yasumatsu I; Takayama G; Hizukuri Y; Ito K; Taira Y; Nannya Y; Tojo A; Watanabe T; Tsutsumi S; Suzuki Y; Uchimaru K
    Nature; 2024 Mar; 627(8002):221-228. PubMed ID: 38383791
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Hypomethylating agents plus venetoclax compared with intensive induction chemotherapy regimens in molecularly defined secondary AML.
    Shimony S; Bewersdorf JP; Shallis RM; Liu Y; Schaefer EJ; Zeidan AM; Goldberg AD; Stein EM; Marcucci G; Lindsley RC; Chen EC; Ramos Perez J; Stein A; DeAngelo DJ; Neuberg DS; Stone RM; Ball B; Stahl M
    Leukemia; 2024 Apr; 38(4):762-768. PubMed ID: 38378841
    [TBL] [Abstract] [Full Text] [Related]  

  • 4.
    Choi YJ; Min YK; Lee ST; Choi JR; Shin S
    Ann Lab Med; 2024 Jul; 44(4):335-342. PubMed ID: 38145892
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms.
    Arribas AJ; Napoli S; Cascione L; Barnabei L; Sartori G; Cannas E; Gaudio E; Tarantelli C; Mensah AA; Spriano F; Zucchetto A; Rossi FM; Rinaldi A; Castro de Moura M; Jovic S; Bordone Pittau R; Stathis A; Stussi G; Gattei V; Brown JR; Esteller M; Zucca E; Rossi D; Bertoni F
    Mol Cancer Ther; 2024 Mar; 23(3):368-380. PubMed ID: 38052765
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Absence of BTK, BCL2, and PLCG2 Mutations in Chronic Lymphocytic leukemia Relapsing after First-Line treatment with Fixed-Duration Ibrutinib plus Venetoclax.
    Jain N; Croner LJ; Allan JN; Siddiqi T; Tedeschi A; Badoux XC; Eckert K; Cheung LWK; Mukherjee A; Dean JP; Szafer-Glusman E; Seymour JF
    Clin Cancer Res; 2024 Feb; 30(3):498-505. PubMed ID: 37955424
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Synchronous T-lymphoblastic lymphoma and neuroblastoma in a 3-yr-old with novel germline
    Tibout P; Livingston J; Kanwar N; Yuki KE; Shlien A; Ngan B; Irwin MS; Morgenstern DA; Hitzler J; Villani A; Cohen-Gogo S
    Cold Spring Harb Mol Case Stud; 2023 Dec; 9(4):. PubMed ID: 37932047
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. MEK/ERK and PI3K/AKT pathway inhibitors affect the transformation of myelodysplastic syndrome into acute myeloid leukemia via H3K27me3 methylases and de‑methylases.
    Zheng Z; Chen X; Zhang Y; Ren F; Ma Y
    Int J Oncol; 2023 Dec; 63(6):. PubMed ID: 37921060
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin (CALR) in exon 3.
    Bonnet S; Carillo S; Legrand B; Burroni B; Lavabre-Bertrand T; Requirand G; Robert N; Fornero L; Al Mansoori A; Moreaux J; Cartron G; Gabellier L; Herbaux C
    Eur J Haematol; 2024 Mar; 112(3):475-478. PubMed ID: 37918825
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-ezh2-CDKN1C axis-driven proliferation in Mantle cell lymphoma.
    Sircar A; Singh S; Xu-Monette ZY; Coyle KM; Hilton LK; Chavdoula E; Ranganathan P; Jain N; Hanel W; Tsichlis P; Alinari L; Peterson BR; Tao J; Muthusamy N; Baiocchi R; Epperla N; Young KH; Morin R; Sehgal L
    Leukemia; 2023 Oct; 37(10):2094-2106. PubMed ID: 37598282
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. [EZH inhibitors in lymphoma therapy].
    Ishitsuka K
    Rinsho Ketsueki; 2023; 64(7):665-669. PubMed ID: 37544728
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Integrative Multi-Omics Analysis of Oncogenic ezh2 Mutants: From Epigenetic Reprogramming to Molecular Signatures.
    Aldana J; Gardner ML; Freitas MA
    Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511137
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Clonal dynamics and copy number variants by single-cell analysis in leukemic evolution of myeloproliferative neoplasms.
    Calabresi L; Carretta C; Romagnoli S; Rotunno G; Parenti S; Bertesi M; Bartalucci N; Rontauroli S; Chiereghin C; Castellano S; Gentili G; Maccari C; Vanderwert F; Mannelli F; Della Porta M; Manfredini R; Vannucchi AM; Guglielmelli P
    Am J Hematol; 2023 Oct; 98(10):1520-1531. PubMed ID: 37399248
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia.
    McCarter JGW; Nemirovsky D; Famulare CA; Farnoud N; Mohanty AS; Stone-Molloy ZS; Chervin J; Ball BJ; Epstein-Peterson ZD; Arcila ME; Stonestrom AJ; Dunbar A; Cai SF; Glass JL; Geyer MB; Rampal RK; Berman E; Abdel-Wahab OI; Stein EM; Tallman MS; Levine RL; Goldberg AD; Papaemmanuil E; Zhang Y; Roshal M; Derkach A; Xiao W
    Blood Adv; 2023 Sep; 7(17):5000-5013. PubMed ID: 37142255
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Postazacitidine clone size predicts long-term outcome of patients with myelodysplastic syndromes and related myeloid neoplasms.
    Nannya Y; Tobiasson M; Sato S; Bernard E; Ohtake S; Takeda J; Creignou M; Zhao L; Kusakabe M; Shibata Y; Nakamura N; Watanabe M; Hiramoto N; Shiozawa Y; Shiraishi Y; Tanaka H; Yoshida K; Kakiuchi N; Makishima H; Nakagawa M; Usuki K; Watanabe M; Imada K; Handa H; Taguchi M; Kiguchi T; Ohyashiki K; Ishikawa T; Takaori-Kondo A; Tsurumi H; Kasahara S; Chiba S; Naoe T; Miyano S; Papaemanuil E; Miyazaki Y; Hellström-Lindberg E; Ogawa S
    Blood Adv; 2023 Jul; 7(14):3624-3636. PubMed ID: 36989067
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. [Analysis of epigenetic modification gene mutations among patients with acute myeloid leukemia].
    Wei J; Qiu H; Zhou H; Chen Z; Miao L; Wang Y; Zhao L; Cai Z
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2023 Apr; 40(4):435-441. PubMed ID: 36972938
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Effects of epigenetic therapy on natural killer cell function and development in hematologic malignancy.
    Lordo MR; Stiff AR; Oakes CC; Mundy-Bosse BL
    J Leukoc Biol; 2023 May; 113(5):518-524. PubMed ID: 36860165
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Atypical chronic myeloid leukemia and myelodysplastic/myeloproliferative neoplasm, not otherwise specified: 2023 update on diagnosis, risk stratification, and management.
    Patnaik MM; Tefferi A
    Am J Hematol; 2023 Apr; 98(4):681-689. PubMed ID: 36601682
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Dual targeting of aberrant DNA and histone methylation synergistically suppresses tumor cell growth in ATL.
    Kurahashi Y; Watanabe T; Yamamoto Y; Ureshino H; Kamachi K; Yoshida-Sakai N; Fukuda-Kurahashi Y; Yamashita S; Hattori N; Nakamura H; Kawaguchi A; Ushijima T; Sueoka E; Kimura S
    Blood Adv; 2023 Apr; 7(8):1545-1559. PubMed ID: 36516085
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Hitting the brakes on accelerated and blast-phase myeloproliferative neoplasms: current and emerging concepts.
    Bewersdorf JP; Rampal RK
    Hematology Am Soc Hematol Educ Program; 2022 Dec; 2022(1):218-224. PubMed ID: 36485103
    [TBL] [Abstract] [Full Text] [Related]  


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