Terms: = Leukemia AND FANCD2, FANCD, 2177, ENSG00000144554, FLJ23826, FAD, FACD, FA4, FA-D2, FAD2, DKFZp762A223
97 results:
1. Simulating Space Conditions Evokes Different DNA Damage Responses in Immature and Mature Cells of the Human Hematopoietic System.
Handwerk L; Schreier HK; Kraft D; Shreder K; Hemmersbach R; Hauslage J; Bonig H; Wiesmüller L; Fournier C; Rall-Scharpf M
Int J Mol Sci; 2023 Sep; 24(18):. PubMed ID: 37762064
[TBL] [Abstract] [Full Text] [Related]
2. Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner.
Wang M; Brandt LTL; Wang X; Russell H; Mitchell E; Kamimae-Lanning AN; Brown JM; Dingler FA; Garaycoechea JI; Isobe T; Kinston SJ; Gu M; Vassiliou GS; Wilson NK; Göttgens B; Patel KJ
Mol Cell; 2023 Jul; 83(14):2417-2433.e7. PubMed ID: 37348497
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3. Phenotypic and genotypic correlation evaluation of 148 pediatric patients with Fanconi anemia in a Chinese rare disease cohort.
Chang L; Zhang L; An W; Wan Y; Cai Y; Lan Y; Zhang A; Liu L; Ruan M; Liu X; Guo Y; Yang W; Chen X; Chen Y; Wang S; Zou Y; Yuan W; Zhu X
Clin Chim Acta; 2023 Jan; 539():41-49. PubMed ID: 36463940
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4. Genetic analysis of a Fanconi anemia case revealed the presence of FANCF mutation (exon 1;469>C-T) with implications to develop acute myeloid leukemia.
Behera CK; Gyandeep G; Mishra R; Mohanty RP; Pal A; Behera J; Samal S; Das B
Mol Biol Rep; 2023 Jan; 50(1):931-936. PubMed ID: 36369330
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5. A Ferroptosis Molecular Subtype-Related Signature for Predicting Prognosis and Response to Chemotherapy in Patients with Chronic Lymphocytic leukemia.
Gong H; Li H; Yang Q; Zhang G; Liu H; Ma Z; Peng H; Nie L; Xiao X; Liu J
Biomed Res Int; 2022; 2022():5646275. PubMed ID: 35845961
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6. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors.
Li C; Su M; Zhu W; Kan W; Ge T; Xu G; Wang S; Sheng L; Gao F; Ye Y; Wang J; Zhou Y; Li J; Liu H
J Med Chem; 2022 Mar; 65(5):4335-4349. PubMed ID: 35200034
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7. Fanconi anemia gene-associated germline predisposition in aplastic anemia and hematologic malignancies.
Nie D; Zhang J; Wang F; Li X; Liu L; Zhang W; Cao P; Chen X; Zhang Y; Chen J; Ma X; Zhou X; Wu Q; Liu M; Liu M; Tian W; Liu H
Front Med; 2022 Jun; 16(3):459-466. PubMed ID: 34741701
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8. Promyelocytic leukemia Proteins Regulate Fanconi Anemia Gene Expression.
Munkhjargal A; Kim MJ; Kim DY; Jeon YJ; Kee YH; Kim LK; Kim YH
Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360546
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9. Hybrid chemotherapy regimen (FLAG-IDA-vincristine-prednisone) for acute leukemia with mixed-phenotype blasts.
Reid JH; Perissinotti AJ; Benitez LL; Boyer D; Lee W; Burke PW; Pettit K; Bixby DL; Marini BL
Leuk Res; 2021 Apr; 103():106539. PubMed ID: 33647818
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10. Synthesis of Carboxamide-Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid leukemia.
Teresa Borrello M; Benelkebir H; Lee A; Hin Tam C; Shafat M; Rushworth SA; Bowles KM; Douglas L; Duriez PJ; Bailey S; Crabb SJ; Packham G; Ganesan A
ChemMedChem; 2021 Apr; 16(8):1316-1324. PubMed ID: 33533576
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11. Whole exome sequencing identifies a novel fancd2 gene splice site mutation associated with disease progression in chronic myeloid leukemia: Implication in targeted therapy of advanced phase CML.
Absar M; Mahmood A; Akhtar T; Basit S; Ramzan K; Jameel A; Afzal S; Ullah A; Qureshi K; Alanazi N; Iqbal Z
Pak J Pharm Sci; 2020 May; 33(3(Special)):1419-1426. PubMed ID: 33361032
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12. An unexpected butadiene diolepoxide-mediated genotoxicity implies alternative mechanism for 1,3-butadiene carcinogenicity.
Nakamura J; Carro S; Gold A; Zhang Z
Chemosphere; 2021 Mar; 266():129149. PubMed ID: 33310515
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13. Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1).
Kanouni T; Severin C; Cho RW; Yuen NY; Xu J; Shi L; Lai C; Del Rosario JR; Stansfield RK; Lawton LN; Hosfield D; O'Connell S; Kreilein MM; Tavares-Greco P; Nie Z; Kaldor SW; Veal JM; Stafford JA; Chen YK
J Med Chem; 2020 Dec; 63(23):14522-14529. PubMed ID: 33034194
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14. High content drug screening for Fanconi anemia therapeutics.
Montanuy H; Camps-Fajol C; Carreras-Puigvert J; Häggblad M; Lundgren B; Aza-Carmona M; Helleday T; Minguillón J; Surrallés J
Orphanet J Rare Dis; 2020 Jun; 15(1):170. PubMed ID: 32605631
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15. Engraftment kinetics after transplantation of double unit cord blood grafts combined with haplo-identical CD34+ cells without antithymocyte globulin.
Politikos I; Devlin SM; Arcila ME; Barone JC; Maloy MA; Naputo KA; Ruiz JD; Mazis CM; Scaradavou A; Avecilla ST; Dahi PB; Giralt SA; Hsu KC; Jakubowski AA; Papadopoulos EB; Perales MA; Sauter CS; Tamari R; Ponce DM; O'Reilly RJ; Barker JN
Leukemia; 2021 Mar; 35(3):850-862. PubMed ID: 32555371
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16. Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors.
Niwa H; Sato S; Handa N; Sengoku T; Umehara T; Yokoyama S
ChemMedChem; 2020 May; 15(9):787-793. PubMed ID: 32166890
[TBL] [Abstract] [Full Text] [Related]
17. Fluorescence spectral detection of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML): A novel photodiagnosis strategy.
Masilamani V; Devanesan S; AlSalhi MS; AlQahtany FS; Farhat KH
Photodiagnosis Photodyn Ther; 2020 Mar; 29():101634. PubMed ID: 31870897
[TBL] [Abstract] [Full Text] [Related]
18. NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia.
Román-Rodríguez FJ; Ugalde L; Álvarez L; Díez B; Ramírez MJ; Risueño C; Cortón M; Bogliolo M; Bernal S; March F; Ayuso C; Hanenberg H; Sevilla J; Rodríguez-Perales S; Torres-Ruiz R; Surrallés J; Bueren JA; Río P
Cell Stem Cell; 2019 Nov; 25(5):607-621.e7. PubMed ID: 31543367
[TBL] [Abstract] [Full Text] [Related]
19. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance.
Tacconi EM; Badie S; De Gregoriis G; Reisländer T; Lai X; Porru M; Folio C; Moore J; Kopp A; Baguña Torres J; Sneddon D; Green M; Dedic S; Lee JW; Batra AS; Rueda OM; Bruna A; Leonetti C; Caldas C; Cornelissen B; Brino L; Ryan A; Biroccio A; Tarsounas M
EMBO Mol Med; 2019 Jul; 11(7):e9982. PubMed ID: 31273933
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20. Regulation of R-loops and genome instability in Fanconi anemia.
Okamoto Y; Hejna J; Takata M
J Biochem; 2019 Jun; 165(6):465-470. PubMed ID: 30821334
[TBL] [Abstract] [Full Text] [Related]
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