BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND FANCD2, FANCD, 2177, ENSG00000144554, FLJ23826, FAD, FACD, FA4, FA-D2, FAD2, DKFZp762A223 AND Treatment
23 results:

  • 1. A Ferroptosis Molecular Subtype-Related Signature for Predicting Prognosis and Response to Chemotherapy in Patients with Chronic Lymphocytic leukemia.
    Gong H; Li H; Yang Q; Zhang G; Liu H; Ma Z; Peng H; Nie L; Xiao X; Liu J
    Biomed Res Int; 2022; 2022():5646275. PubMed ID: 35845961
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors.
    Li C; Su M; Zhu W; Kan W; Ge T; Xu G; Wang S; Sheng L; Gao F; Ye Y; Wang J; Zhou Y; Li J; Liu H
    J Med Chem; 2022 Mar; 65(5):4335-4349. PubMed ID: 35200034
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Hybrid chemotherapy regimen (FLAG-IDA-vincristine-prednisone) for acute leukemia with mixed-phenotype blasts.
    Reid JH; Perissinotti AJ; Benitez LL; Boyer D; Lee W; Burke PW; Pettit K; Bixby DL; Marini BL
    Leuk Res; 2021 Apr; 103():106539. PubMed ID: 33647818
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Fluorescence spectral detection of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML): A novel photodiagnosis strategy.
    Masilamani V; Devanesan S; AlSalhi MS; AlQahtany FS; Farhat KH
    Photodiagnosis Photodyn Ther; 2020 Mar; 29():101634. PubMed ID: 31870897
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia.
    Román-Rodríguez FJ; Ugalde L; Álvarez L; Díez B; Ramírez MJ; Risueño C; Cortón M; Bogliolo M; Bernal S; March F; Ayuso C; Hanenberg H; Sevilla J; Rodríguez-Perales S; Torres-Ruiz R; Surrallés J; Bueren JA; Río P
    Cell Stem Cell; 2019 Nov; 25(5):607-621.e7. PubMed ID: 31543367
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance.
    Tacconi EM; Badie S; De Gregoriis G; Reisländer T; Lai X; Porru M; Folio C; Moore J; Kopp A; Baguña Torres J; Sneddon D; Green M; Dedic S; Lee JW; Batra AS; Rueda OM; Bruna A; Leonetti C; Caldas C; Cornelissen B; Brino L; Ryan A; Biroccio A; Tarsounas M
    EMBO Mol Med; 2019 Jul; 11(7):e9982. PubMed ID: 31273933
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.
    Schulz-Fincke J; Hau M; Barth J; Robaa D; Willmann D; Kürner A; Haas J; Greve G; Haydn T; Fulda S; Lübbert M; Lüdeke S; Berg T; Sippl W; Schüle R; Jung M
    Eur J Med Chem; 2018 Jan; 144():52-67. PubMed ID: 29247860
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Potent induction of apoptosis by givinostat in BCR-ABL1-positive and BCR-ABL1-negative precursor B-cell acute lymphoblastic leukemia cell lines.
    Yao C; Zhang G; Walker A; Zhao KY; Li Y; Lyu L; Tang Y; Ru P; Jones D; Zhao W
    Leuk Res; 2017 Sep; 60():129-134. PubMed ID: 28818808
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331.
    Mitchell HR; Lu X; Myers RM; Sung L; Balsamo LM; Carroll WL; Raetz E; Loh ML; Mattano LA; Winick NJ; Devidas M; Hunger SP; Maloney K; Kadan-Lottick NS
    Int J Cancer; 2016 Jan; 138(2):332-9. PubMed ID: 26235006
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease.
    Maes T; Mascaró C; Ortega A; Lunardi S; Ciceri F; Somervaille TC; Buesa C
    Epigenomics; 2015; 7(4):609-26. PubMed ID: 26111032
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Mechanisms of resistance to BCR-ABL TKIs and the therapeutic strategies: A review.
    Yang K; Fu LW
    Crit Rev Oncol Hematol; 2015 Mar; 93(3):277-92. PubMed ID: 25500000
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Proteomic analysis reveals a FANCA-modulated neddylation pathway involved in CXCR5 membrane targeting and cell mobility.
    Renaudin X; Guervilly JH; Aoufouchi S; Rosselli F
    J Cell Sci; 2014 Aug; 127(Pt 16):3546-54. PubMed ID: 25015289
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The impact of fancd2 deficiency on formaldehyde-induced toxicity in human lymphoblastoid cell lines.
    Ren X; Ji Z; McHale CM; Yuh J; Bersonda J; Tang M; Smith MT; Zhang L
    Arch Toxicol; 2013 Jan; 87(1):189-96. PubMed ID: 22872141
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Fanconi anemia.
    Soulier J
    Hematology Am Soc Hematol Educ Program; 2011; 2011():492-7. PubMed ID: 22160080
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines.
    Bernard ME; Kim H; Berhane H; Epperly MW; Franicola D; Zhang X; Houghton F; Shields D; Wang H; Bakkenist CJ; Frantz MC; Forbeck EM; Goff JP; Wipf P; Greenberger JS
    Radiat Res; 2011 Nov; 176(5):603-12. PubMed ID: 21939290
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Functional and physical interaction between the mismatch repair and FA-BRCA pathways.
    Williams SA; Wilson JB; Clark AP; Mitson-Salazar A; Tomashevski A; Ananth S; Glazer PM; Semmes OJ; Bale AE; Jones NJ; Kupfer GM
    Hum Mol Genet; 2011 Nov; 20(22):4395-410. PubMed ID: 21865299
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.
    Binda C; Valente S; Romanenghi M; Pilotto S; Cirilli R; Karytinos A; Ciossani G; Botrugno OA; Forneris F; Tardugno M; Edmondson DE; Minucci S; Mattevi A; Mai A
    J Am Chem Soc; 2010 May; 132(19):6827-33. PubMed ID: 20415477
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The Fanconi anemia pathway and ubiquitin.
    Jacquemont C; Taniguchi T
    BMC Biochem; 2007 Nov; 8 Suppl 1(Suppl 1):S10. PubMed ID: 18047734
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. A novel Leu153Ser mutation of the Fanconi anemia fancd2 gene is associated with severe chemotherapy toxicity in a pediatric T-cell acute lymphoblastic leukemia.
    Borriello A; Locasciulli A; Bianco AM; Criscuolo M; Conti V; Grammatico P; Cappellacci S; Zatterale A; Morgese F; Cucciolla V; Delia D; Della Ragione F; Savoia A
    Leukemia; 2007 Jan; 21(1):72-8. PubMed ID: 17096012
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Relevance of DT-diaphorase activity to mitomycin C (MMC) efficacy on human cancer cells: differences in in vitro and in vivo systems.
    Nishiyama M; Saeki S; Aogi K; Hirabayashi N; Toge T
    Int J Cancer; 1993 Apr; 53(6):1013-6. PubMed ID: 8473041
    [TBL] [Abstract] [Full Text] [Related]  


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