BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND FGFR1, CEK, 2260, ENSG00000077782, P11362, FLT2, CD331, H3, HBGFR, FGFBR, H5, KAL2, H2, BFGFR, N-SAM, H4
1435 results:

  • 1. Regulation of cytokine and chemokine expression by histone lysine methyltransferase MLL1 in rheumatoid arthritis synovial fibroblasts.
    Okamoto K; Araki Y; Aizaki Y; Tanaka S; Kadono Y; Mimura T
    Sci Rep; 2024 May; 14(1):10610. PubMed ID: 38719857
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody.
    Stefańczyk SA; Hagelstein I; Lutz MS; Müller S; Holzmayer SJ; Jarjour G; Zekri L; Heitmann JS; Salih HR; Märklin M
    Blood Cancer J; 2024 Apr; 14(1):67. PubMed ID: 38637557
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Unlocking adult T-cell leukemia/lymphoma's epigenetic secrets: delving into the mechanism and impact of EZH1/2 inhibition.
    Tavakoli Shirazi P; Bywater MJ
    Immunol Cell Biol; 2024; 102(5):298-301. PubMed ID: 38606590
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Discovery of the First-in-Class G9a/GLP PROTAC Degrader.
    Velez J; Han Y; Yim H; Yang P; Deng Z; Park KS; Kabir M; Kaniskan HÜ; Xiong Y; Jin J
    J Med Chem; 2024 Apr; 67(8):6397-6409. PubMed ID: 38602846
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.
    Shomali W; Gotlib J
    Am J Hematol; 2024 May; 99(5):946-968. PubMed ID: 38551368
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Discovery of novel benzimidazole derivatives as potent HDACs inhibitors against leukemia with (Thio)Hydantoin as zinc-binding moiety: Design, synthesis, enzyme inhibition, and cellular mechanistic study.
    Abdulwahab HG; Mansour RE; Farghaly TA; El-Sehrawi HM
    Bioorg Chem; 2024 May; 146():107284. PubMed ID: 38493640
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Bahcc1 is critical for the aberrant epigenetic program in a mouse model of MLL-ENL-mediated leukemia.
    Nakamura A; Masuya M; Shinmei M; Tawara I; Nosaka T; Ono R
    Blood Adv; 2024 May; 8(9):2193-2206. PubMed ID: 38452334
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts.
    Francois AK; Rohani A; Loftus M; Dochnal S; Hrit J; McFarlane S; Whitford A; Lewis A; Krakowiak P; Boutell C; Rothbart SB; Kashatus D; Cliffe AR
    mBio; 2024 Apr; 15(4):e0327823. PubMed ID: 38411116
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Mechanisms of action and resistance in histone methylation-targeted therapy.
    Yamagishi M; Kuze Y; Kobayashi S; Nakashima M; Morishima S; Kawamata T; Makiyama J; Suzuki K; Seki M; Abe K; Imamura K; Watanabe E; Tsuchiya K; Yasumatsu I; Takayama G; Hizukuri Y; Ito K; Taira Y; Nannya Y; Tojo A; Watanabe T; Tsutsumi S; Suzuki Y; Uchimaru K
    Nature; 2024 Mar; 627(8002):221-228. PubMed ID: 38383791
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Extending MeCP2 interactome: canonical nucleosomal histones interact with MeCP2.
    Ortega-Alarcon D; Claveria-Gimeno R; Vega S; Kalani L; Jorge-Torres OC; Esteller M; Ausio J; Abian O; Velazquez-Campoy A
    Nucleic Acids Res; 2024 Apr; 52(7):3636-3653. PubMed ID: 38321951
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Expression and Clinical Significance of CD30 and CD56 in Lymphoblastic Lymphoma: A Retrospective Analysis on Paraffin-Embedded Tissues by Immunohistochemistry.
    Li S; Zheng S; Huang X; Zhang W; Liu F; Cao Q
    Fetal Pediatr Pathol; 2024; 43(2):111-122. PubMed ID: 38213180
    [No Abstract]    [Full Text] [Related]  

  • 12. Myeloid and lymphoid neoplasm with novel complex translocation: unusual case report with T-lymphoblastic lymphoma, myeloid hyperplasia, eosinophilia, basophilia, and t(1;8;10)( (p31;q24;q11.2).
    Aljabry MS
    J Hematop; 2023 Mar; 16(1):27-31. PubMed ID: 38175368
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies.
    Voon HPJ; Hii L; Garvie A; Udugama M; Krug B; Russo C; Chüeh AC; Daly RJ; Morey A; Bell TDM; Turner SJ; Rosenbluh J; Daniel P; Firestein R; Mann JR; Collas P; Jabado N; Wong LH
    Genome Biol; 2023 Dec; 24(1):284. PubMed ID: 38066546
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Clinical whole-genome sequencing and FISH identify two different fusion partners for NUP98 in a patient with acute myeloid leukemia: A case report.
    Mojarad BA; Crees ZD; Schroeder MC; Xiang Z; Vader J; Sina J; Jacoby M; Frater JL; Duncavage EJ; Spencer DH; Lavine K; Neidich JA; Amarillo I
    Cancer Genet; 2024 Jan; 280-281():1-5. PubMed ID: 38056049
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Rational design and optimization of novel 4-methyl quinazoline derivatives as PI3K/HDAC dual inhibitors with benzamide as zinc binding moiety for the treatment of acute myeloid leukemia.
    Zhang K; Huang R; Ji M; Lin S; Lai F; Wu D; Tian H; Bi J; Peng S; Hu J; Sheng L; Li Y; Chen X; Xu H
    Eur J Med Chem; 2024 Jan; 264():116015. PubMed ID: 38048697
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. T cell phenotype and lack of eosinophilia are not uncommon in extramedullary myeloid/lymphoid neoplasms with ETV6::FLT3 fusion: a case report and review of the literature.
    Schoelinck J; Gervasoni J; Guillermin Y; Beillard E; Pissaloux D; Chassagne-Clement C
    Virchows Arch; 2024 May; 484(5):853-857. PubMed ID: 37985498
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. MEK/ERK and PI3K/AKT pathway inhibitors affect the transformation of myelodysplastic syndrome into acute myeloid leukemia via H3K27me3 methylases and de‑methylases.
    Zheng Z; Chen X; Zhang Y; Ren F; Ma Y
    Int J Oncol; 2023 Dec; 63(6):. PubMed ID: 37921060
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Formaldehyde regulates
    Pham VN; Bruemmer KJ; Toh JDW; Ge EJ; Tenney L; Ward CC; Dingler FA; Millington CL; Garcia-Prieto CA; Pulos-Holmes MC; Ingolia NT; Pontel LB; Esteller M; Patel KJ; Nomura DK; Chang CJ
    Science; 2023 Nov; 382(6670):eabp9201. PubMed ID: 37917677
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in preclinical models.
    Ge G; Zhang P; Sui P; Chen S; Yang H; Guo Y; Rubalcava IP; Noor A; Delma CR; Agosto-Peña J; Geng H; Medina EA; Liang Y; Nimer SD; Mesa R; Abdel-Wahab O; Xu M; Yang FC
    J Clin Invest; 2024 Jan; 134(1):. PubMed ID: 37917239
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells.
    Reisbeck L; Linder B; Tascher G; Bozkurt S; Weber KJ; Herold-Mende C; van Wijk SJL; Marschalek R; Schaefer L; Münch C; Kögel D
    Am J Physiol Cell Physiol; 2023 Dec; 325(6):C1451-C1469. PubMed ID: 37899749
    [TBL] [Abstract] [Full Text] [Related]  


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