BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND FGFR1, CEK, 2260, ENSG00000077782, P11362, FLT2, CD331, H3, HBGFR, FGFBR, H5, KAL2, H2, BFGFR, N-SAM, H4 AND Treatment
392 results:

  • 1. Regulation of cytokine and chemokine expression by histone lysine methyltransferase MLL1 in rheumatoid arthritis synovial fibroblasts.
    Okamoto K; Araki Y; Aizaki Y; Tanaka S; Kadono Y; Mimura T
    Sci Rep; 2024 May; 14(1):10610. PubMed ID: 38719857
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody.
    Stefańczyk SA; Hagelstein I; Lutz MS; Müller S; Holzmayer SJ; Jarjour G; Zekri L; Heitmann JS; Salih HR; Märklin M
    Blood Cancer J; 2024 Apr; 14(1):67. PubMed ID: 38637557
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.
    Shomali W; Gotlib J
    Am J Hematol; 2024 May; 99(5):946-968. PubMed ID: 38551368
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Mechanisms of action and resistance in histone methylation-targeted therapy.
    Yamagishi M; Kuze Y; Kobayashi S; Nakashima M; Morishima S; Kawamata T; Makiyama J; Suzuki K; Seki M; Abe K; Imamura K; Watanabe E; Tsuchiya K; Yasumatsu I; Takayama G; Hizukuri Y; Ito K; Taira Y; Nannya Y; Tojo A; Watanabe T; Tsutsumi S; Suzuki Y; Uchimaru K
    Nature; 2024 Mar; 627(8002):221-228. PubMed ID: 38383791
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Rational design and optimization of novel 4-methyl quinazoline derivatives as PI3K/HDAC dual inhibitors with benzamide as zinc binding moiety for the treatment of acute myeloid leukemia.
    Zhang K; Huang R; Ji M; Lin S; Lai F; Wu D; Tian H; Bi J; Peng S; Hu J; Sheng L; Li Y; Chen X; Xu H
    Eur J Med Chem; 2024 Jan; 264():116015. PubMed ID: 38048697
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. MEK/ERK and PI3K/AKT pathway inhibitors affect the transformation of myelodysplastic syndrome into acute myeloid leukemia via H3K27me3 methylases and de‑methylases.
    Zheng Z; Chen X; Zhang Y; Ren F; Ma Y
    Int J Oncol; 2023 Dec; 63(6):. PubMed ID: 37921060
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells.
    Reisbeck L; Linder B; Tascher G; Bozkurt S; Weber KJ; Herold-Mende C; van Wijk SJL; Marschalek R; Schaefer L; Münch C; Kögel D
    Am J Physiol Cell Physiol; 2023 Dec; 325(6):C1451-C1469. PubMed ID: 37899749
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Dietary γ-mangostin triggers immunogenic cell death and activates cGAS signaling in acute myeloid leukemia.
    Long ZJ; Wang JD; Qiu SX; Zhang Y; Wu SJ; Lei XX; Huang ZW; Chen JJ; Yang YL; Zhang XZ; Liu Q
    Pharmacol Res; 2023 Nov; 197():106973. PubMed ID: 37898441
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.
    Gray ZH; Chakraborty D; Duttweiler RR; Alekbaeva GD; Murphy SE; Chetal K; Ji F; Ferman BI; Honer MA; Wang Z; Myers C; Sun R; Kaniskan HÜ; Toma MM; Bondarenko EA; Santoro JN; Miranda C; Dillingham ME; Tang R; Gozani O; Jin J; Skorski T; Duy C; Lee H; Sadreyev RI; Whetstine JR
    Cell; 2023 Oct; 186(21):4528-4545.e18. PubMed ID: 37788669
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The emerging role of DOT1L in cell proliferation and differentiation: Friend or foe.
    Wu D; Zhang J; Jun Y; Liu L; Huang C; Wang W; Yang C; Xiang Z; Wu J; Huang Y; Meng D; Yang Z; Zhou X; Cheng C; Yang J
    Histol Histopathol; 2024 Apr; 39(4):425-435. PubMed ID: 37706592
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma.
    Sircar A; Singh S; Xu-Monette ZY; Coyle KM; Hilton LK; Chavdoula E; Ranganathan P; Jain N; Hanel W; Tsichlis P; Alinari L; Peterson BR; Tao J; Muthusamy N; Baiocchi R; Epperla N; Young KH; Morin R; Sehgal L
    Leukemia; 2023 Oct; 37(10):2094-2106. PubMed ID: 37598282
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Preconditioning of radiotherapy enhances efficacy of B7-H3-CAR-T in treating solid tumor models.
    Wang T; Zhang K; You F; Ma R; Yang N; Tian S; An G; Yang L
    Life Sci; 2023 Oct; 331():122024. PubMed ID: 37574043
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Integrative Multi-Omics Analysis of Oncogenic EZH2 Mutants: From Epigenetic Reprogramming to Molecular Signatures.
    Aldana J; Gardner ML; Freitas MA
    Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511137
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. ATF4 renders human T-cell acute lymphoblastic leukemia cell resistance to fgfr1 inhibitors through amino acid metabolic reprogramming.
    Zhang ZJ; Wu QF; Ren AQ; Chen Q; Shi JZ; Li JP; Liu XY; Zhang ZJ; Tang YZ; Zhao Y; Yao NN; Zhang XY; Liu CP; Dong G; Zhao JX; Xu MJ; Yue YQ; Hu J; Sun F; Liu Y; Ao QL; Zhou FL; Wu H; Zhang TC; Zhu HC
    Acta Pharmacol Sin; 2023 Nov; 44(11):2282-2295. PubMed ID: 37280363
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus.
    Kleijwegt C; Bressac F; Seurre C; Bouchereau W; Cohen C; Texier P; Simonet T; Schaeffer L; Lomonte P; Corpet A
    Elife; 2023 May; 12():. PubMed ID: 37227756
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Synergetic effect of Azacitidine and Sorafenib in treatment of a case of myeloid neoplasm with sole chromosomal abnormality t(8;22)(p11.2;q11.2)/BCR-fgfr1 rearrangement.
    Dhangar S; Shanmukhaiah C; Sawant L; Ghatanatti J; Shah A; Mathan S LP; Vundinti BR
    Cancer Genet; 2023 Jun; 274-275():26-29. PubMed ID: 36965231
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Pemigatinib for the treatment of myeloid/lymphoid neoplasms with
    Freyer CW; Hughes ME; Carulli A; Bagg A; Hexner E
    Expert Rev Anticancer Ther; 2023 Apr; 23(4):351-359. PubMed ID: 36927350
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Chimeric Antigen Receptor T-cell Therapy in Cancer: A Critical Review.
    Sharma R; Suravarjhula L; Banerjee M; Kumar G; Kumar N
    Curr Drug Res Rev; 2023; 15(3):241-261. PubMed ID: 36825696
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
    Kamens JL; Nance S; Koss C; Xu B; Cotton A; Lam JW; Garfinkle EAR; Nallagatla P; Smith AMR; Mitchell S; Ma J; Currier D; Wright WC; Kavdia K; Pagala VR; Kim W; Wallace LM; Cho JH; Fan Y; Seth A; Twarog N; Choi JK; Obeng EA; Hatley ME; Metzger ML; Inaba H; Jeha S; Rubnitz JE; Peng J; Chen T; Shelat AA; Guy RK; Gruber TA
    Nat Commun; 2023 Feb; 14(1):809. PubMed ID: 36781850
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Myeloid/lymphoid neoplasm with eosinophilia and BCR/fgfr1 rearrangement with transformation to cortical T-lymphoblastic lymphoma and erythroid precursors: a case report.
    Isaza AP; Quintero SC; González LPQ; Córdoba FEA; Olivar AFA; Ocaña JCB
    J Med Case Rep; 2023 Jan; 17(1):39. PubMed ID: 36698221
    [TBL] [Abstract] [Full Text] [Related]  


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