Terms: = Leukemia AND FOXO1, Q12778, FOXO1A, 2308, ENSG00000150907, FKH1, FKHR AND Treatment
39 results:
1. foxo1 enhances CAR T cell stemness, metabolic fitness and efficacy.
Chan JD; Scheffler CM; Munoz I; Sek K; Lee JN; Huang YK; Yap KM; Saw NYL; Li J; Chen AXY; Chan CW; Derrick EB; Todd KL; Tong J; Dunbar PA; Li J; Hoang TX; de Menezes MN; Petley EV; Kim JS; Nguyen D; Leung PSK; So J; Deguit C; Zhu J; House IG; Kats LM; Scott AM; Solomon BJ; Harrison SJ; Oliaro J; Parish IA; Quinn KM; Neeson PJ; Slaney CY; Lai J; Beavis PA; Darcy PK
Nature; 2024 May; 629(8010):201-210. PubMed ID: 38600376
[TBL] [Abstract] [Full Text] [Related]
2. Down-regulation of Musashi-2 exerts antileukemic effects on acute lymphoblastic leukemia cells and increases sensitivity to dexamethasone.
Zou D; Lv M; Chen Y; Niu T; Ma C; Shi C; Huang Z; Wu Y; Yang S; Wang Y; Wu N; Zhang Y; Ouyang G; Mu Q
Ann Hematol; 2024 Jan; 103(1):141-151. PubMed ID: 37749318
[TBL] [Abstract] [Full Text] [Related]
3. foxo1 promotes the expression of canonical WNT target genes in examined basal-like breast and glioblastoma multiforme cancer cells.
Pintor S; Lopez A; Flores D; Lozoya B; Soti B; Pokhrel R; Negrete J; Persans MW; Gilkerson R; Gunn B; Keniry M
FEBS Open Bio; 2023 Nov; 13(11):2108-2123. PubMed ID: 37584250
[TBL] [Abstract] [Full Text] [Related]
4. The discrete roles of individual FOXO transcription factor family members in B-cell malignancies.
Lees J; Hay J; Moles MW; Michie AM
Front Immunol; 2023; 14():1179101. PubMed ID: 37275916
[TBL] [Abstract] [Full Text] [Related]
5. Identification of oxidative stress-related genes differentially expressed in Alzheimer's disease and construction of a hub gene-based diagnostic model.
Zhang Y; Kiryu H
Sci Rep; 2023 Apr; 13(1):6817. PubMed ID: 37100862
[TBL] [Abstract] [Full Text] [Related]
6. A foxo1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.
Jang JY; Hwang I; Pan H; Yao J; Alinari L; Imada E; Zanettini C; Kluk MJ; Wang Y; Lee Y; Lin HV; Huang X; Di Liberto M; Chen Z; Ballman KV; Cantley LC; Marchionni L; Inghirami G; Elemento O; Baiocchi RA; Chen-Kiang S; Belvedere S; Zheng H; Paik J
J Clin Invest; 2022 Dec; 132(24):. PubMed ID: 36282572
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7. Inhibition of acylglycerol kinase sensitizes DLBCL to venetoclax via upregulation of foxo1-mediated BCL-2 expression.
Ning N; Zhang S; Wu Q; Li X; Kuang D; Duan Y; Xia M; Liu H; Weng J; Ba H; Tang Z; Cheng X; Mei H; Huang L; Ao Q; Wang G; Hu Y; Laurence A; Wang J; Wang G; Yang XP
Theranostics; 2022; 12(12):5537-5550. PubMed ID: 35910796
[No Abstract] [Full Text] [Related]
8. Exportin-1 is critical for cell proliferation and survival in adult T cell leukemia.
Ishikawa C; Mori N
Invest New Drugs; 2022 Aug; 40(4):718-727. PubMed ID: 35477814
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9. Resveratrol Induces the Fasting State and Alters Circadian Metabolism in Hepatocytes.
Chatam O; Chapnik N; Froy O
Plant Foods Hum Nutr; 2022 Mar; 77(1):128-134. PubMed ID: 35178649
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10. Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells.
Zhang H; Yin SL; Wang LH; Jia LN; Su GY; Liu XQ; Zhou F; Breslin P; Meng R; Li QY; Yang JY; Wu CF
Chin J Nat Med; 2021 Aug; 19(8):608-620. PubMed ID: 34419260
[TBL] [Abstract] [Full Text] [Related]
11. FLT3 inhibition upregulates HDAC8 via FOXO to inactivate p53 and promote maintenance of FLT3-ITD+ acute myeloid leukemia.
Long J; Jia MY; Fang WY; Chen XJ; Mu LL; Wang ZY; Shen Y; Xiang RF; Wang LN; Wang L; Jiang CH; Jiang JL; Zhang WJ; Sun YD; Chang L; Gao WH; Wang Y; Li JM; Hong DL; Liang AB; Hu J
Blood; 2020 Apr; 135(17):1472-1483. PubMed ID: 32315388
[TBL] [Abstract] [Full Text] [Related]
12. Potential CD34 signaling through phosphorylated-BAD in chemotherapy-resistant acute myeloid leukemia.
Yiau SK; Lee C; Mohd Tohit ER; Chang KM; Abdullah M
J Recept Signal Transduct Res; 2019 Jun; 39(3):276-282. PubMed ID: 31509041
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13. Estradiol promotes trophoblast viability and invasion by activating SGK1.
He WH; Jin MM; Liu AP; Zhou Y; Hu XL; Zhu YM; Liu AX
Biomed Pharmacother; 2019 Sep; 117():109092. PubMed ID: 31203134
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14. Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines.
Prabhu KS; Siveen KS; Kuttikrishnan S; Jochebeth A; Ali TA; Elareer NR; Iskandarani A; Quaiyoom Khan A; Merhi M; Dermime S; El-Elimat T; Oberlies NH; Alali FQ; Steinhoff M; Uddin S
Biomolecules; 2019 Mar; 9(4):. PubMed ID: 30934922
[TBL] [Abstract] [Full Text] [Related]
15. AKT/mTORC2 Inhibition Activates foxo1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival.
Cosimo E; Tarafdar A; Moles MW; Holroyd AK; Malik N; Catherwood MA; Hay J; Dunn KM; Macdonald AM; Guichard SM; O'Rourke D; Leach MT; Sansom OJ; Cosulich SC; McCaig AM; Michie AM
Clin Cancer Res; 2019 Mar; 25(5):1574-1587. PubMed ID: 30559170
[TBL] [Abstract] [Full Text] [Related]
16. Overexpression of Hes1 is involved in sensitization of K562 cells to Imatinib.
Eskandari S; Yazdanparast R
J Cell Biochem; 2019 Jun; 120(6):10128-10136. PubMed ID: 30548309
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17. Combing metabolomics with bioanalysis methods to study the antitumor mechanism of the new acridone derivative 8q on CCRF-CEM cells: 8q induced mitochondrial-mediated apoptosis and targeted the PI3K/AKT/foxo1 pathway.
Wang N; Zhang B; Jin F; Gao D; Liu F; Liu H; Jiang Y
J Pharm Biomed Anal; 2018 Oct; 160():314-322. PubMed ID: 30114609
[TBL] [Abstract] [Full Text] [Related]
18. Novel combined Ato-C treatment synergistically suppresses proliferation of Bcr-Abl-positive leukemic cells in vitro and in vivo.
Wahiduzzaman M; Ota A; Karnan S; Hanamura I; Mizuno S; Kanasugi J; Rahman ML; Hyodo T; Konishi H; Tsuzuki S; Takami A; Hosokawa Y
Cancer Lett; 2018 Oct; 433():117-130. PubMed ID: 29944906
[TBL] [Abstract] [Full Text] [Related]
19. Tight regulation of foxo1 is essential for maintenance of B-cell precursor acute lymphoblastic leukemia.
Wang F; Demir S; Gehringer F; Osswald CD; Seyfried F; Enzenmüller S; Eckhoff SM; Maier T; Holzmann K; Debatin KM; Wirth T; Meyer LH; Ushmorov A
Blood; 2018 Jun; 131(26):2929-2942. PubMed ID: 29622548
[TBL] [Abstract] [Full Text] [Related]
20. Transcriptomic analysis of the PI3K/Akt signaling pathway reveals the dual role of the c-Jun oncogene in cytotoxicity and the development of resistance in HL-60 leukemia cells in response to arsenic trioxide.
Roszak J; Smok-Pieniążek A; Stępnik M
Adv Clin Exp Med; 2017 Dec; 26(9):1335-1342. PubMed ID: 29442453
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