BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND GMPS, ENSG00000163655, 8833
27 results:

  • 1. Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation.
    Zhang Y; Zhou Y; Li X; Pan X; Bai J; Chen Y; Lai Z; Chen Q; Ma F; Dong Y
    Stem Cell Res Ther; 2024 Apr; 15(1):100. PubMed ID: 38589882
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Identification of Cell Type-Specific Effects of
    Bae SG; Kim HJ; Kim MY; Kim DDH; Shin SI; Ahn JS; Park J
    Mol Cells; 2023 Oct; 46(10):611-626. PubMed ID: 37853686
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Single-cell resolution reveals RalA GTPase expanding hematopoietic stem cells and facilitating of BCR-ABL1-driven leukemogenesis in a CRISPR/Cas9 gene editing mouse model.
    Yin Z; Su R; Ge L; Wang X; Yang J; Huang G; Li C; Liu Y; Zhang K; Deng L; Fei J
    Int J Biol Sci; 2023; 19(4):1211-1227. PubMed ID: 36923939
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Progenitor Hierarchy of Chronic Myelomonocytic leukemia Identifies Inflammatory Monocytic-Biased Trajectory Linked to Worse Outcomes.
    Ferrall-Fairbanks MC; Dhawan A; Johnson B; Newman H; Volpe V; Letson C; Ball M; Hunter AM; Balasis ME; Kruer T; Ben-Crentsil NA; Kroeger JL; Balderas R; Komrokji RS; Sallman DA; Zhang J; Bejar R; Altrock PM; Padron E
    Blood Cancer Discov; 2022 Nov; 3(6):536-553. PubMed ID: 36053528
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Chromatin remodeling subunit BRM and valine regulate hematopoietic stem/progenitor cell function and self-renewal via intrinsic and extrinsic effects.
    Naidu SR; Capitano M; Ropa J; Cooper S; Huang X; Broxmeyer HE
    Leukemia; 2022 Mar; 36(3):821-833. PubMed ID: 34599272
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact.
    Schönherz AA; Bødker JS; Schmitz A; Brøndum RF; Jakobsen LH; Roug AS; Severinsen MT; El-Galaly TC; Jensen P; Johnsen HE; Bøgsted M; Dybkær K
    PLoS One; 2020; 15(4):e0229593. PubMed ID: 32324791
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Cellular and molecular architecture of hematopoietic stem cells and progenitors in genetic models of bone marrow failure.
    Heidemann S; Bursic B; Zandi S; Li H; Abelson S; Klaassen RJ; Abish S; Rayar M; Breakey VR; Moshiri H; Dhanraj S; de Borja R; Shlien A; Dick JE; Dror Y
    JCI Insight; 2020 Feb; 5(4):. PubMed ID: 31990679
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.
    Chen X; Burkhardt DB; Hartman AA; Hu X; Eastman AE; Sun C; Wang X; Zhong M; Krishnaswamy S; Guo S
    Nat Commun; 2019 Dec; 10(1):5767. PubMed ID: 31852898
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Pathway genes and metabolites in thiopurine therapy in Korean children with acute lymphoblastic leukaemia.
    Choi R; Sohn I; Kim MJ; Woo HI; Lee JW; Ma Y; Yi ES; Koo HH; Lee SY
    Br J Clin Pharmacol; 2019 Jul; 85(7):1585-1597. PubMed ID: 30927276
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity.
    Lau BW; Huh K; Madero-Marroquin R; De Marchi F; Lim Y; Wang Q; Lobo F; Marchionni L; Smith DB; DeZern A; Levis MJ; Aplan PD; Matsui W; Gondek LP
    Oncogene; 2019 Jan; 38(5):687-698. PubMed ID: 30171262
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. GMP-ing to Spatial Conclusions about Emergency and Leukemic Myelopoiesis.
    Niederkorn M; Starczynowski DT
    Cell Stem Cell; 2017 May; 20(5):579-581. PubMed ID: 28475879
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Architectural and functional heterogeneity of hematopoietic stem/progenitor cells in non-del(5q) myelodysplastic syndromes.
    Chesnais V; Arcangeli ML; Delette C; Rousseau A; Guermouche H; Lefevre C; Bondu S; Diop M; Cheok M; Chapuis N; Legros L; Raynaud S; Willems L; Bouscary D; Lauret E; Bernard OA; Kosmider O; Pflumio F; Fontenay M
    Blood; 2017 Jan; 129(4):484-496. PubMed ID: 27856460
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Targeting of the MNK-eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function.
    Lim S; Saw TY; Zhang M; Janes MR; Nacro K; Hill J; Lim AQ; Chang CT; Fruman DA; Rizzieri DA; Tan SY; Fan H; Chuah CT; Ong ST
    Proc Natl Acad Sci U S A; 2013 Jun; 110(25):E2298-307. PubMed ID: 23737503
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.
    Pang WW; Pluvinage JV; Price EA; Sridhar K; Arber DA; Greenberg PL; Schrier SL; Park CY; Weissman IL
    Proc Natl Acad Sci U S A; 2013 Feb; 110(8):3011-6. PubMed ID: 23388639
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Cell of origin determines clinically relevant subtypes of MLL-rearranged AML.
    Krivtsov AV; Figueroa ME; Sinha AU; Stubbs MC; Feng Z; Valk PJ; Delwel R; Döhner K; Bullinger L; Kung AL; Melnick AM; Armstrong SA
    Leukemia; 2013 Apr; 27(4):852-60. PubMed ID: 23235717
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.
    Bindels EM; Havermans M; Lugthart S; Erpelinck C; Wocjtowicz E; Krivtsov AV; Rombouts E; Armstrong SA; Taskesen E; Haanstra JR; Beverloo HB; Döhner H; Hudson WA; Kersey JH; Delwel R; Kumar AR
    Blood; 2012 Jun; 119(24):5838-49. PubMed ID: 22553314
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.
    Reckzeh K; Bereshchenko O; Mead A; Rehn M; Kharazi S; Jacobsen SE; Nerlov C; Cammenga J
    Leukemia; 2012 Jul; 26(7):1527-36. PubMed ID: 22318449
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex.
    Heuser M; Yun H; Berg T; Yung E; Argiropoulos B; Kuchenbauer F; Park G; Hamwi I; Palmqvist L; Lai CK; Leung M; Lin G; Chaturvedi A; Thakur BK; Iwasaki M; Bilenky M; Thiessen N; Robertson G; Hirst M; Kent D; Wilson NK; Göttgens B; Eaves C; Cleary ML; Marra M; Ganser A; Humphries RK
    Cancer Cell; 2011 Jul; 20(1):39-52. PubMed ID: 21741595
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  • 19. A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.
    Klinakis A; Lobry C; Abdel-Wahab O; Oh P; Haeno H; Buonamici S; van De Walle I; Cathelin S; Trimarchi T; Araldi E; Liu C; Ibrahim S; Beran M; Zavadil J; Efstratiadis A; Taghon T; Michor F; Levine RL; Aifantis I
    Nature; 2011 May; 473(7346):230-3. PubMed ID: 21562564
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. PML is a key component for the differentiation of myeloid progenitor cells to macrophages.
    Khalfin-Rabinovich Y; Weinstein A; Levi BZ
    Int Immunol; 2011 Apr; 23(4):287-96. PubMed ID: 21427174
    [TBL] [Abstract] [Full Text] [Related]  


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