BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND HMGA1, MGC4242, 3159, ENSG00000137309, MGC12816, HMGIY, P17096, MGC4854, HMG-R
22 results:

  • 1. The acidic domain of Hmga2 and the domain's linker region are critical for driving self-renewal of hematopoietic stem cell.
    Sun Y; Kubota S; Iimori M; Hamashima A; Murakami H; Bai J; Morii M; Yokomizo-Nakano T; Osato M; Araki K; Sashida G
    Int J Hematol; 2022 Apr; 115(4):553-562. PubMed ID: 35067851
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Critical role of the high mobility group A proteins in hematological malignancies.
    De Martino M; Esposito F; Fusco A
    Hematol Oncol; 2022 Feb; 40(1):2-10. PubMed ID: 34637548
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Prediction of neuroblastoma cell response to treatment with natural or synthetic retinoids using selected protein biomarkers.
    Dobrotkova V; Chlapek P; Jezova M; Adamkova K; Mazanek P; Sterba J; Veselska R
    PLoS One; 2019; 14(6):e0218269. PubMed ID: 31188873
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. PTML Combinatorial Model of ChEMBL Compounds Assays for Multiple Types of Cancer.
    Bediaga H; Arrasate S; González-Díaz H
    ACS Comb Sci; 2018 Nov; 20(11):621-632. PubMed ID: 30240186
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Cell competition is a tumour suppressor mechanism in the thymus.
    Martins VC; Busch K; Juraeva D; Blum C; Ludwig C; Rasche V; Lasitschka F; Mastitsky SE; Brors B; Hielscher T; Fehling HJ; Rodewald HR
    Nature; 2014 May; 509(7501):465-70. PubMed ID: 24828041
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Human surfactant protein D alters oxidative stress and hmga1 expression to induce p53 apoptotic pathway in eosinophil leukemic cell line.
    Mahajan L; Pandit H; Madan T; Gautam P; Yadav AK; Warke H; Sundaram CS; Sirdeshmukh R; Sarma PU; Kishore U; Surolia A
    PLoS One; 2013; 8(12):e85046. PubMed ID: 24391984
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Inactivation of the Cdkn2a locus cooperates with hmga1 to drive T-cell leukemogenesis.
    Di Cello F; Dhara S; Hristov AC; Kowalski J; Elbahloul O; Hillion J; Roy S; Meijerink JP; Winter SS; Larson RS; Huso DL; Resar L
    Leuk Lymphoma; 2013 Aug; 54(8):1762-8. PubMed ID: 23311322
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. High mobility group A1 protein acts as a new target of Notch1 signaling and regulates cell proliferation in T leukemia cells.
    Xi Y; Li YS; Tang HB
    Mol Cell Biochem; 2013 Feb; 374(1-2):173-80. PubMed ID: 23229232
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. hmga1 is differentially expressed and mediates silencing of the CD4/CD8 loci in T cell lineages and leukemic cells.
    Xi Y; Watanabe S; Hino Y; Sakamoto C; Nakatsu Y; Okada S; Nakao M
    Cancer Sci; 2012 Mar; 103(3):439-47. PubMed ID: 22106824
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. hmga1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis.
    Schuldenfrei A; Belton A; Kowalski J; Talbot CC; Di Cello F; Poh W; Tsai HL; Shah SN; Huso TH; Huso DL; Resar LM
    BMC Genomics; 2011 Nov; 12():549. PubMed ID: 22053823
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Flavopiridol induces BCL-2 expression and represses oncogenic transcription factors in leukemic blasts from adults with refractory acute myeloid leukemia.
    Nelson DM; Joseph B; Hillion J; Segal J; Karp JE; Resar LM
    Leuk Lymphoma; 2011 Oct; 52(10):1999-2006. PubMed ID: 21728742
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. [Analysis of relationship between bcr-abl transcription level detected by real-time quantitative polymerase chain reaction and clinical status of CML patients].
    Wang GR; Yu Z; Zhao YZ; Li ZJ; Li CH; Qian LS; Qiu LG
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2009 Aug; 17(4):861-5. PubMed ID: 19698217
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?
    Hillion J; Dhara S; Sumter TF; Mukherjee M; Di Cello F; Belton A; Turkson J; Jaganathan S; Cheng L; Ye Z; Jove R; Aplan P; Lin YW; Wertzler K; Reeves R; Elbahlouh O; Kowalski J; Bhattacharya R; Resar LM
    Cancer Res; 2008 Dec; 68(24):10121-7. PubMed ID: 19074878
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The HMGA proteins: a myriad of functions (Review).
    Cleynen I; Van de Ven WJ
    Int J Oncol; 2008 Feb; 32(2):289-305. PubMed ID: 18202751
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and hmga1.
    Nagel S; Scherr M; Kel A; Hornischer K; Crawford GE; Kaufmann M; Meyer C; Drexler HG; MacLeod RA
    Cancer Res; 2007 Feb; 67(4):1461-71. PubMed ID: 17308084
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Cryptic 6p21.3 duplications and triplication involving hmga1 partially masked by add 6p in four cases of myelodysplasia.
    Andrieux J; Geffroy S; Bilhou-Nabera C; Dupriez B; Demory JL; Bauters F; Laï JL; Dastugue N
    Cancer Genet Cytogenet; 2006 Jan; 164(1):84-7. PubMed ID: 16364769
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The HMG-I oncogene causes highly penetrant, aggressive lymphoid malignancy in transgenic mice and is overexpressed in human leukemia.
    Xu Y; Sumter TF; Bhattacharya R; Tesfaye A; Fuchs EJ; Wood LJ; Huso DL; Resar LM
    Cancer Res; 2004 May; 64(10):3371-5. PubMed ID: 15150086
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. High-mobility group A1 proteins are overexpressed in human leukaemias.
    Pierantoni GM; Agosti V; Fedele M; Bond H; Caliendo I; Chiappetta G; Lo Coco F; Pane F; Turco MC; Morrone G; Venuta S; Fusco A
    Biochem J; 2003 May; 372(Pt 1):145-50. PubMed ID: 12573034
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Further considerations on the intranuclear distribution of HMGI/Y proteins.
    Tabellini G; Riccio M; Baldini G; Bareggi R; Billi AM; Grill V; Narducci P; Martelli AM
    Ital J Anat Embryol; 2001; 106(3):251-60. PubMed ID: 11767201
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Repression of interleukin-2 and interleukin-4 promoters by tumor suppressor protein p53.
    Pesch J; Brehm U; Staib C; Grummt F
    J Interferon Cytokine Res; 1996 Aug; 16(8):595-600. PubMed ID: 8877730
    [TBL] [Abstract] [Full Text] [Related]  


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