Terms: = Leukemia AND HOXA9, HOX1, 3205, ENSG00000078399, HOX1G, P31269
394 results:
1. A novel t(X;21)(p11.4;q22.12) translocation adds to the role of BCOR and RUNX1 in myelodysplastic syndromes and acute myeloid leukemias.
Mavridou E; Lema Fernandez AG; Nardelli C; Pierini V; Quintini M; Arniani S; Di Giacomo D; Crescenzi B; Matteucci C; Sambani C; Mecucci C
Genes Chromosomes Cancer; 2024 Apr; 63(4):e23235. PubMed ID: 38656651
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2. Discovery of novel pyrrolo[2,3-d]pyrimidines as potent menin-mixed lineage leukemia interaction inhibitors.
Bai H; Yang Z; Lei H; Wu Y; Liu J; Yuan B; Ma M; Gao L; Zhang SQ; Xin M
Eur J Med Chem; 2024 Mar; 268():116226. PubMed ID: 38367493
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3. RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein hoxa9.
Zhang M; Hyle J; Chen X; Xin Y; Jin Y; Zhang J; Yang X; Chen X; Wright S; Liu Z; Rosikiewicz W; Xu B; He L; Liu H; Ping N; Wu D; Wen F; Li C; Xu P
Genome Biol; 2024 Jan; 25(1):16. PubMed ID: 38216972
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4. [Effects of
Li Y; Shi LH; Xie X; Fan PK
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2023 Dec; 31(6):1599-1607. PubMed ID: 38071034
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5. MEIS inhibitors reduce the viability of primary leukemia cells and Stem cells by inducing apoptosis.
Meriç N; Albayrak E; Gülbaş Z; Kocabaş F
Leuk Lymphoma; 2024 Feb; 65(2):187-198. PubMed ID: 37902585
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6. SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML.
Di Mambro A; Arroyo-Berdugo Y; Fioretti T; Randles M; Cozzuto L; Rajeeve V; Cevenini A; Austin MJ; Esposito G; Ponomarenko J; Lucas CM; Cutillas P; Gribben J; Williams O; Calle Y; Patel B; Esposito MT
Oncogene; 2023 Dec; 42(50):3670-3683. PubMed ID: 37891368
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7. Identification and analysis of methylation signature genes and association with immune infiltration in pediatric acute myeloid leukemia.
Zhu H; Xu Y; Xia J; Guo X; Fang Y; Fan J; Li F; Wu J; Zheng G; Liu Y
J Cancer Res Clin Oncol; 2023 Nov; 149(16):14965-14982. PubMed ID: 37606761
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8. Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert T; Hsu CJ; Becker AL; Graessle S; Horne A; Bemmann F; Zhang Q; Heuser M; Vasioukhin V; Scholl S; Hochhaus A; Siegerist F; Endlich N; Bullinger L; Lane SW; Haas S; Schnoeder TM; Heidel FH
Leukemia; 2023 Oct; 37(10):2027-2035. PubMed ID: 37587260
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9. Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.
Oka M; Otani M; Miyamoto Y; Oshima R; Adachi J; Tomonaga T; Asally M; Nagaoka Y; Tanaka K; Toyoda A; Ichikawa K; Morishita S; Isono K; Koseki H; Nakato R; Ohkawa Y; Yoneda Y
Cell Rep; 2023 Aug; 42(8):112884. PubMed ID: 37516964
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10. Clinical implication and potential function of ARHGEF6 in acute myeloid leukemia: An in vitro study.
Li K; Wang H; Yang C; Li C; Xue B; Zhou J
PLoS One; 2023; 18(4):e0283934. PubMed ID: 37027440
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11. Validation of the prognostic significance of the 2022 European leukemiaNet risk stratification system in intensive chemotherapy treated aged 18 to 65 years patients with de novo acute myeloid leukemia.
Lo MY; Tsai XC; Lin CC; Tien FM; Kuo YY; Lee WH; Peng YL; Liu MC; Tseng MH; Hsu CA; Chen JC; Lin LI; Sun HI; Chuang YK; Ko BS; Tang JL; Yao M; Chou WC; Hou HA; Tien HF
Am J Hematol; 2023 May; 98(5):760-769. PubMed ID: 36861732
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12. A comprehensive landscape of transcription profiles and data resources for human leukemia.
Luo M; Miao YR; Ke YJ; Guo AY; Zhang Q
Blood Adv; 2023 Jul; 7(14):3435-3449. PubMed ID: 36595475
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13. hoxa9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia.
Agrawal-Singh S; Bagri J; Giotopoulos G; Azazi DMA; Horton SJ; Lopez CK; Anand S; Bach AS; Stedham F; Antrobus R; Houghton JW; Vassiliou GS; Sasca D; Yun H; Whetton AD; Huntly BJP
Blood; 2023 Apr; 141(14):1737-1754. PubMed ID: 36577137
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14.
Wang W; Li H; Huang M; Wang X; Li W; Qian X; Jing L
Open Biol; 2022 Oct; 12(10):220172. PubMed ID: 36285442
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15. 17β-neriifolin from unripe fruits of Cerbera manghas suppressed cell proliferation via the inhibition of hoxa9-dependent transcription and the induction of apoptosis in the human AML cell line THP-1.
Takase S; Yun YS; Moriya F; Sekine S; Yotsumoto S; Miyake K; Yahagi T; Ito A; Inoue H
J Nat Med; 2023 Jan; 77(1):180-187. PubMed ID: 36266527
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16. LncRNA MAFG-AS1-induced acute myeloid leukemia development via modulating miR-147b/hoxa9.
Yao Q; Zhang L; Liu Z; Yu L; Wang Y; Liu J; Wang Y
Environ Sci Pollut Res Int; 2023 Feb; 30(7):19250-19258. PubMed ID: 36229729
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17. hoxa9 has the hallmarks of a biological switch with implications in blood cancers.
Talarmain L; Clarke MA; Shorthouse D; Cabrera-Cosme L; Kent DG; Fisher J; Hall BA
Nat Commun; 2022 Oct; 13(1):5829. PubMed ID: 36192425
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18. Panobinostat (LBH589) increase survival in adult xenografic model of acute lymphoblastic leukemia with t(4;11) but promotes antagonistic effects in combination with MTX and 6MP.
Moreno DA; Junior HLR; Laranjeira ABA; Cruzeiro GAV; Borges KS; Salomão KB; Ramalho FS; Yunes JA; Silva CLA; Rego EM; Scrideli CA; Tone LG
Med Oncol; 2022 Sep; 39(12):216. PubMed ID: 36175721
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19. Bioinformatic Analyses of Broad H3K79me2 Domains in Different leukemia Cell Line Data Sets.
Sharma P; Sattarifard H; Fatemiyan N; Lakowski TM; Davie JR
Cells; 2022 Sep; 11(18):. PubMed ID: 36139405
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20. MiR-27a downregulates 14-3-3θ, RUNX1, AF4, and MLL-AF4, crucial drivers of blast transformation in t(4;11) leukemia cells.
Fioretti T; Zanobio M; Raia M; Errichiello S; Izzo B; Cattaneo F; Ammendola R; Cevenini A; Esposito G
Cell Biochem Funct; 2022 Oct; 40(7):706-717. PubMed ID: 35981137
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