Terms: = Leukemia AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884
373 results:
1. On the mechanism of wogonin against acute monocytic leukemia using network pharmacology and experimental validation.
Wang X; Wang Y; Chen J; Wang Q; Liu Z; Yin Y; Yang T; Shen T; Sa Y
Sci Rep; 2024 May; 14(1):10114. PubMed ID: 38698063
[TBL] [Abstract] [Full Text] [Related]
2. Targeted delivery of hsp90 inhibitors for efficient therapy of CD44-positive acute myeloid leukemia and solid tumor-colon cancer.
Jia L; Yang H; Liu Y; Zhou Y; Li G; Zhou Q; Xu Y; Huang Z; Ye F; Ye J; Liu A; Ji C
J Nanobiotechnology; 2024 Apr; 22(1):198. PubMed ID: 38649957
[TBL] [Abstract] [Full Text] [Related]
3. ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells.
Valdez BC; Yuan B; Murray D; Ramdial JL; Popat U; Nieto Y; Andersson BS
Oncotarget; 2024 Mar; 15():220-231. PubMed ID: 38484153
[TBL] [Abstract] [Full Text] [Related]
4. Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2
Ichikawa T; Suekane A; Nakahata S; Iha H; Shimoda K; Murakami T; Morishita K
Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38474089
[TBL] [Abstract] [Full Text] [Related]
5. Bacterial heat shock protein genes during induction chemotherapy in pediatric patients with acute lymphoblastic leukemia.
Dunn KA; MacDonald E; MacDonald T; Kulkarni K
Future Oncol; 2024 Jan; 20(1):17-23. PubMed ID: 38189148
[No Abstract] [Full Text] [Related]
6. JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers.
Lu X; Yu R; Li Z; Yang M; Dai J; Liu M
Cancer Lett; 2024 Feb; 582():216517. PubMed ID: 38101609
[TBL] [Abstract] [Full Text] [Related]
7. Co-targeting hsp90 alpha and CDK7 overcomes resistance against hsp90 inhibitors in BCR-ABL1+ leukemia cells.
Vogt M; Dienstbier N; Schliehe-Diecks J; Scharov K; Tu JW; Gebing P; Hogenkamp J; Bilen BS; Furlan S; Picard D; Remke M; Yasin L; Bickel D; Kalia M; Iacoangeli A; Lenz T; Stühler K; Pandyra AA; Hauer J; Fischer U; Wagener R; Borkhardt A; Bhatia S
Cell Death Dis; 2023 Dec; 14(12):799. PubMed ID: 38057328
[TBL] [Abstract] [Full Text] [Related]
8. A Coumarin-Imidazothiadiazole Derivative, SP11 Abrogates Tumor Growth by Targeting hsp90 and Its Client Proteins.
Nirgude S; Shahana M V ; Ravindran F; Kumar S; Sharma S; Mahadeva R; Mhatre A; Karki SS; Choudhary B
Molecules; 2023 Jul; 28(13):. PubMed ID: 37446888
[TBL] [Abstract] [Full Text] [Related]
9. Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells.
Carter BZ; Mak PY; Muftuoglu M; Tao W; Ke B; Pei J; Bedoy AD; Ostermann LB; Nishida Y; Isgandarova S; Sobieski M; Nguyen N; Powell RT; Martinez-Moczygemba M; Stephan C; Basyal M; Pemmaraju N; Boettcher S; Ebert BL; Shpall EJ; Wallner B; Morgan RA; Karras GI; Moll UM; Andreeff M
Blood; 2023 Sep; 142(12):1056-1070. PubMed ID: 37339579
[TBL] [Abstract] [Full Text] [Related]
10. Synthesis of new antiproliferative 1,3,4-substituted-pyrrolo[3,2-c]quinoline derivatives, biological and in silico insights.
Mingoia F; Di Sano C; D'Anna C; Fazzari M; Minafra L; Bono A; La Monica G; Martorana A; Almerico AM; Lauria A
Eur J Med Chem; 2023 Oct; 258():115537. PubMed ID: 37329715
[TBL] [Abstract] [Full Text] [Related]
11. Heat shock factor 1 is a promising therapeutic target against adult T-cell leukemia.
Ishikawa C; Mori N
Med Oncol; 2023 May; 40(6):172. PubMed ID: 37165174
[TBL] [Abstract] [Full Text] [Related]
12. Role of Ganetespib, an hsp90 Inhibitor, in Cancer Therapy: From Molecular Mechanisms to Clinical Practice.
Youssef ME; Cavalu S; Hasan AM; Yahya G; Abd-Eldayem MA; Saber S
Int J Mol Sci; 2023 Mar; 24(5):. PubMed ID: 36902446
[TBL] [Abstract] [Full Text] [Related]
13. Alvespimycin Inhibits Heat Shock Protein 90 and Overcomes Imatinib Resistance in Chronic Myeloid leukemia Cell Lines.
Alves R; Santos D; Jorge J; Gonçalves AC; Catarino S; Girão H; Melo JB; Sarmento-Ribeiro AB
Molecules; 2023 Jan; 28(3):. PubMed ID: 36770876
[TBL] [Abstract] [Full Text] [Related]
14. Heat shock protein 90 inhibitors induce cell differentiation via the ubiquitin-dependent aurora kinase A degradation in a MPLW515L mouse model of primary myelofibrosis.
Wang F; Zhang H; He B; Liu Z; Wu X; Liu Y; Xu X; Gou X; Wang H; Yang Q
Hematol Oncol; 2023 Aug; 41(3):474-486. PubMed ID: 36422297
[TBL] [Abstract] [Full Text] [Related]
15. Effects of cancer-associated point mutations on the structure, function, and stability of isocitrate dehydrogenase 2.
Chen X; Yang P; Qiao Y; Ye F; Wang Z; Xu M; Han X; Song L; Wu Y; Ou WB
Sci Rep; 2022 Nov; 12(1):18830. PubMed ID: 36335201
[TBL] [Abstract] [Full Text] [Related]
16. Mebendazole's Conformational Space and Its Predicted Binding to Human Heat-Shock Protein 90.
Fiedler W; Freisleben F; Wellbrock J; Kirschner KN
J Chem Inf Model; 2022 Aug; 62(15):3604-3617. PubMed ID: 35867562
[TBL] [Abstract] [Full Text] [Related]
17. Mutated KIT Tyrosine Kinase as a Novel Molecular Target in Acute Myeloid leukemia.
Katagiri S; Chi S; Minami Y; Fukushima K; Shibayama H; Hosono N; Yamauchi T; Morishita T; Kondo T; Yanada M; Yamamoto K; Kuroda J; Usuki K; Akahane D; Gotoh A
Int J Mol Sci; 2022 Apr; 23(9):. PubMed ID: 35563085
[TBL] [Abstract] [Full Text] [Related]
18. Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid leukemia.
Bruserud Ø; Reikvam H; Brenner AK
Molecules; 2022 Jan; 27(3):. PubMed ID: 35163998
[TBL] [Abstract] [Full Text] [Related]
19. [The Relationship between PPP2R5C and Molt-4 Cell Viability, hsp90-GR Signal in Childhood Acute T Lymphocytic leukemia].
Liu L; Li HT; Zheng HY; Dang HB
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2022 Feb; 30(1):84-91. PubMed ID: 35123608
[TBL] [Abstract] [Full Text] [Related]
20. Inhibition of adult T-cell leukemia cell proliferation by polymerized proanthocyanidin from blueberry leaves through JAK proteolysis.
Ichikawa T; Sugamoto K; Matsuura Y; Kunitake H; Shimoda K; Morishita K
Cancer Sci; 2022 Apr; 113(4):1406-1416. PubMed ID: 35100463
[TBL] [Abstract] [Full Text] [Related]
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