Terms: = Leukemia AND IL6ST, CDw130, 3572, ENSG00000134352, P40189, IL6R-beta, GP130-RAPS, GP130, CD130
504 results:
1. Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in mice.
Zhao S; Deng H; Lu Y; Tao Y; Li D; Jiang X; Wei X; Chen X; Ma F; Wang Y; Gou L; Yang J
BMC Immunol; 2024 Aug; 25(1):56. PubMed ID: 39169307
[TBL] [Abstract] [Full Text] [Related]
2. IL-6 Blockade in Cytokine Storm Syndromes.
Barrett D
Adv Exp Med Biol; 2024; 1448():565-572. PubMed ID: 39117839
[TBL] [Abstract] [Full Text] [Related]
3. A mechanistic PK/PD model of AZD0171 (anti-LIF) to support Phase II dose selection.
Shahraz A; Penney M; Candido J; Opoku-Ansah G; Neubauer M; Eyles J; Ojo O; Liu N; Luheshi NM; Phipps A; Vishwanathan K
CPT Pharmacometrics Syst Pharmacol; 2024 Oct; 13(10):1670-1681. PubMed ID: 39041713
[TBL] [Abstract] [Full Text] [Related]
4. Mutations in LIFR rewire the JAK/STAT signaling pathway: A study unveiling mechanistic details of Stüve-Wiedemann syndrome.
Paul I; Roy A; Chakrabarti D; Nandi C; Ray S
Comput Biol Med; 2024 Sep; 179():108797. PubMed ID: 38968765
[TBL] [Abstract] [Full Text] [Related]
5. Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR.
Rafii P; Cruz PR; Ettich J; Seibel C; Padrini G; Wittich C; Lang A; Petzsch P; Köhrer K; Moll JM; Floss DM; Scheller J
J Biol Chem; 2024 May; 300(5):107251. PubMed ID: 38569939
[TBL] [Abstract] [Full Text] [Related]
6. Interleukin-6 Family of Cytokines in Cancers.
Zaporowska-Stachowiak I; Springer M; Stachowiak K; Oduah M; Sopata M; Wieczorowska-Tobis K; Bryl W
J Interferon Cytokine Res; 2024 Feb; 44(2):45-59. PubMed ID: 38232478
[TBL] [Abstract] [Full Text] [Related]
7. Oncostatin M: Dual Regulator of the Skeletal and Hematopoietic Systems.
Sims NA; Lévesque JP
Curr Osteoporos Rep; 2024 Feb; 22(1):80-95. PubMed ID: 38198032
[TBL] [Abstract] [Full Text] [Related]
8. [Clinical and molecular biological characterization of patients with accelerated chronic lymphocytic leukemia].
Zhou ZY; Dai LMJ; Sha YQ; Qiu TL; Qin SC; Miao Y; Xia Y; Wu W; Tang HN; Xu W; Li JY; Zhu HY
Zhonghua Xue Ye Xue Za Zhi; 2023 Nov; 44(11):917-923. PubMed ID: 38185521
[No Abstract] [Full Text] [Related]
9. Empagliflozin Reverses Oxidized LDL-Induced RECK Suppression, Cardiotrophin-1 Expression, MMP Activation, and Human Aortic Smooth Muscle Cell Proliferation and Migration.
Chandrasekar B; Mummidi S; DeMarco VG; Higashi Y
Mediators Inflamm; 2023; 2023():6112301. PubMed ID: 37830075
[TBL] [Abstract] [Full Text] [Related]
10. Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes.
Rafii P; Seibel C; Weitz HT; Ettich J; Minafra AR; Petzsch P; Lang A; Floss DM; Behnke K; Köhrer K; Moll JM; Scheller J
Commun Biol; 2023 Apr; 6(1):418. PubMed ID: 37061565
[TBL] [Abstract] [Full Text] [Related]
11. Evaluation of diagnostic efficacy of NRP-1/CD304 in hematological diseases.
Liu YJ; Li XH; Song YL; Zhou YC; Cai RZ; Chi PD
Cancer Med; 2023 May; 12(10):11284-11292. PubMed ID: 36965095
[TBL] [Abstract] [Full Text] [Related]
12. Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment.
Hallett RM; Bonfill-Teixidor E; Iurlaro R; Arias A; Raman S; Bayliss P; Egorova O; Neva-Alejo A; McGray AR; Lau E; Bosch A; Beilschmidt M; Maetzel D; Fransson J; Huber-Ruano I; Anido J; Julien JP; Giblin P; Seoane J
Clin Cancer Res; 2023 Feb; 29(4):791-804. PubMed ID: 36441800
[TBL] [Abstract] [Full Text] [Related]
13. Human IL-17 and TNF-α Additively or Synergistically Regulate the Expression of Proinflammatory Genes, Coagulation-Related Genes, and Tight Junction Genes in Porcine Aortic Endothelial Cells.
Li W; Chen P; Zhao Y; Cao M; Hu W; Pan L; Sun H; Huang D; Wu H; Song Z; Zhong H; Mou L; Luan S; Chen X; Gao H
Front Immunol; 2022; 13():857311. PubMed ID: 35844613
[TBL] [Abstract] [Full Text] [Related]
14. The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights.
Halder S; Parte S; Kshirsagar P; Muniyan S; Nair HB; Batra SK; Seshacharyulu P
Biochim Biophys Acta Rev Cancer; 2022 Jul; 1877(4):188737. PubMed ID: 35680099
[TBL] [Abstract] [Full Text] [Related]
15. Altered expression of leukemia inhibitory factor (LIF), LIFR, gp130, and IL11 in the embryo implantation site of rat model with prenatal androgen-induced polycystic ovary syndrome.
Javidan M; Changaei M; Ramezani Tehrani F; Mosaffa N; Noroozzadeh M; Hosseinzadeh R; Rajaei S
Biochem Biophys Res Commun; 2022 May; 605():24-30. PubMed ID: 35306361
[TBL] [Abstract] [Full Text] [Related]
16. The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure.
Kubin T; Gajawada P; Bramlage P; Hein S; Berge B; Cetinkaya A; Burger H; Schönburg M; Schaper W; Choi YH; Richter M
Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163735
[TBL] [Abstract] [Full Text] [Related]
17. IL-6 Cytokine Family: A Putative Target for Breast Cancer Prevention and Treatment.
Felcher CM; Bogni ES; Kordon EC
Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163731
[TBL] [Abstract] [Full Text] [Related]
18. Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells.
Lindkvist M; Zegeye MM; Grenegård M; Ljungberg LU
Int J Mol Sci; 2022 Jan; 23(3):. PubMed ID: 35163371
[TBL] [Abstract] [Full Text] [Related]
19. A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma.
Amet R; Previtali V; Mihigo HB; Sheridan E; Brophy S; Hante NK; Santos-Martinez MJ; Hayden PJ; Browne PV; Rozas I; McElligott AM; Zisterer DM
Life Sci; 2022 Feb; 290():120236. PubMed ID: 34953891
[TBL] [Abstract] [Full Text] [Related]
20. gp130 Cytokines Activate Novel Signaling Pathways and Alter Bone Dissemination in ER+ Breast Cancer Cells.
Omokehinde T; Jotte A; Johnson RW
J Bone Miner Res; 2022 Feb; 37(2):185-201. PubMed ID: 34477239
[TBL] [Abstract] [Full Text] [Related]
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