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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND IL6ST, CDw130, 3572, ENSG00000134352, P40189, IL6R-beta, GP130-RAPS, GP130, CD130
504 results:

  • 1. Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in mice.
    Zhao S; Deng H; Lu Y; Tao Y; Li D; Jiang X; Wei X; Chen X; Ma F; Wang Y; Gou L; Yang J
    BMC Immunol; 2024 Aug; 25(1):56. PubMed ID: 39169307
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. IL-6 Blockade in Cytokine Storm Syndromes.
    Barrett D
    Adv Exp Med Biol; 2024; 1448():565-572. PubMed ID: 39117839
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. A mechanistic PK/PD model of AZD0171 (anti-LIF) to support Phase II dose selection.
    Shahraz A; Penney M; Candido J; Opoku-Ansah G; Neubauer M; Eyles J; Ojo O; Liu N; Luheshi NM; Phipps A; Vishwanathan K
    CPT Pharmacometrics Syst Pharmacol; 2024 Oct; 13(10):1670-1681. PubMed ID: 39041713
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Mutations in LIFR rewire the JAK/STAT signaling pathway: A study unveiling mechanistic details of Stüve-Wiedemann syndrome.
    Paul I; Roy A; Chakrabarti D; Nandi C; Ray S
    Comput Biol Med; 2024 Sep; 179():108797. PubMed ID: 38968765
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR.
    Rafii P; Cruz PR; Ettich J; Seibel C; Padrini G; Wittich C; Lang A; Petzsch P; Köhrer K; Moll JM; Floss DM; Scheller J
    J Biol Chem; 2024 May; 300(5):107251. PubMed ID: 38569939
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Interleukin-6 Family of Cytokines in Cancers.
    Zaporowska-Stachowiak I; Springer M; Stachowiak K; Oduah M; Sopata M; Wieczorowska-Tobis K; Bryl W
    J Interferon Cytokine Res; 2024 Feb; 44(2):45-59. PubMed ID: 38232478
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Oncostatin M: Dual Regulator of the Skeletal and Hematopoietic Systems.
    Sims NA; Lévesque JP
    Curr Osteoporos Rep; 2024 Feb; 22(1):80-95. PubMed ID: 38198032
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. [Clinical and molecular biological characterization of patients with accelerated chronic lymphocytic leukemia].
    Zhou ZY; Dai LMJ; Sha YQ; Qiu TL; Qin SC; Miao Y; Xia Y; Wu W; Tang HN; Xu W; Li JY; Zhu HY
    Zhonghua Xue Ye Xue Za Zhi; 2023 Nov; 44(11):917-923. PubMed ID: 38185521
    [No Abstract]    [Full Text] [Related]  

  • 9. Empagliflozin Reverses Oxidized LDL-Induced RECK Suppression, Cardiotrophin-1 Expression, MMP Activation, and Human Aortic Smooth Muscle Cell Proliferation and Migration.
    Chandrasekar B; Mummidi S; DeMarco VG; Higashi Y
    Mediators Inflamm; 2023; 2023():6112301. PubMed ID: 37830075
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes.
    Rafii P; Seibel C; Weitz HT; Ettich J; Minafra AR; Petzsch P; Lang A; Floss DM; Behnke K; Köhrer K; Moll JM; Scheller J
    Commun Biol; 2023 Apr; 6(1):418. PubMed ID: 37061565
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Evaluation of diagnostic efficacy of NRP-1/CD304 in hematological diseases.
    Liu YJ; Li XH; Song YL; Zhou YC; Cai RZ; Chi PD
    Cancer Med; 2023 May; 12(10):11284-11292. PubMed ID: 36965095
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment.
    Hallett RM; Bonfill-Teixidor E; Iurlaro R; Arias A; Raman S; Bayliss P; Egorova O; Neva-Alejo A; McGray AR; Lau E; Bosch A; Beilschmidt M; Maetzel D; Fransson J; Huber-Ruano I; Anido J; Julien JP; Giblin P; Seoane J
    Clin Cancer Res; 2023 Feb; 29(4):791-804. PubMed ID: 36441800
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Human IL-17 and TNF-α Additively or Synergistically Regulate the Expression of Proinflammatory Genes, Coagulation-Related Genes, and Tight Junction Genes in Porcine Aortic Endothelial Cells.
    Li W; Chen P; Zhao Y; Cao M; Hu W; Pan L; Sun H; Huang D; Wu H; Song Z; Zhong H; Mou L; Luan S; Chen X; Gao H
    Front Immunol; 2022; 13():857311. PubMed ID: 35844613
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights.
    Halder S; Parte S; Kshirsagar P; Muniyan S; Nair HB; Batra SK; Seshacharyulu P
    Biochim Biophys Acta Rev Cancer; 2022 Jul; 1877(4):188737. PubMed ID: 35680099
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Altered expression of leukemia inhibitory factor (LIF), LIFR, gp130, and IL11 in the embryo implantation site of rat model with prenatal androgen-induced polycystic ovary syndrome.
    Javidan M; Changaei M; Ramezani Tehrani F; Mosaffa N; Noroozzadeh M; Hosseinzadeh R; Rajaei S
    Biochem Biophys Res Commun; 2022 May; 605():24-30. PubMed ID: 35306361
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure.
    Kubin T; Gajawada P; Bramlage P; Hein S; Berge B; Cetinkaya A; Burger H; Schönburg M; Schaper W; Choi YH; Richter M
    Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163735
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. IL-6 Cytokine Family: A Putative Target for Breast Cancer Prevention and Treatment.
    Felcher CM; Bogni ES; Kordon EC
    Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163731
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells.
    Lindkvist M; Zegeye MM; Grenegård M; Ljungberg LU
    Int J Mol Sci; 2022 Jan; 23(3):. PubMed ID: 35163371
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma.
    Amet R; Previtali V; Mihigo HB; Sheridan E; Brophy S; Hante NK; Santos-Martinez MJ; Hayden PJ; Browne PV; Rozas I; McElligott AM; Zisterer DM
    Life Sci; 2022 Feb; 290():120236. PubMed ID: 34953891
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. gp130 Cytokines Activate Novel Signaling Pathways and Alter Bone Dissemination in ER+ Breast Cancer Cells.
    Omokehinde T; Jotte A; Johnson RW
    J Bone Miner Res; 2022 Feb; 37(2):185-201. PubMed ID: 34477239
    [TBL] [Abstract] [Full Text] [Related]  


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