BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND IL7R, P16871, IL-7R-alpha, CDW127, CD127, ENSG00000168685, 3575 AND Prognosis
23 results:

  • 1. IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition.
    Courtois L; Cabannes-Hamy A; Kim R; Delecourt M; Pinton A; Charbonnier G; Feroul M; Smith C; Tueur G; Pivert C; Balducci E; Simonin M; Angel LH; Spicuglia S; Boissel N; Andrieu GP; Asnafi V; Rousselot P; Lhermitte L
    Blood; 2023 Jul; 142(2):158-171. PubMed ID: 37023368
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Low il7r Expression at Diagnosis Predicted Relapse in Adult Acute Myeloid leukemia Patients With t(8;21).
    Xu N; Sun K; Wang YZ; Chen WM; Wang J; Li LD; Wang X; Hao Y; Chang Y; Liu YR; Huang XJ; Qin YZ
    Front Immunol; 2022; 13():909104. PubMed ID: 35874754
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Adverse prognostic impact of complex karyotype (≥3 cytogenetic alterations) in adult T-cell acute lymphoblastic leukemia (T-ALL).
    Genescà E; Morgades M; González-Gil C; Fuster-Tormo F; Haferlach C; Meggendorfer M; Montesinos P; Barba P; Gil C; Coll R; Moreno MJ; Martínez-Carballeira D; García-Cadenas I; Vives S; Ribera J; González-Campos J; Díaz-Beya M; Mercadal S; Artola MT; Cladera A; Tormo M; Bermúdez A; Vall-Llovera F; Martínez-Sánchez P; Amigo ML; Monsalvo S; Novo A; Cervera M; García-Guiñon A; Ciudad J; Cervera J; Hernández-Rivas JM; Granada I; Haferlach T; Orfao A; Solé F; Ribera JM
    Leuk Res; 2021 Oct; 109():106612. PubMed ID: 34139642
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. CD4
    Pan Y; Wang H; An F; Wu F; Tao Q; Li Y; Ruan Y; Zhai Z
    Int Immunopharmacol; 2021 Jul; 96():107742. PubMed ID: 33984717
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. [Gene Mutation in Acute Lymphoblastic leukemia by DNA Sequencing].
    Zheng RY; Wang SJ; Wang C; Li T; Liao LX; Li ML; Chen SM; Guo R; Wang WQ; Zhang Y; Fan Y; Wan DM; Liu YF
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2020 Dec; 28(6):1791-1795. PubMed ID: 33283700
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. [Analysis of Clinical Characteristics and Therapeutic Efficacy of Patients with Adult Acute Lymphoblastic leukemia].
    Xu TT; Wang WM; Fu GM; Wang JM; Jiang ZX
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2020 Feb; 28(1):68-75. PubMed ID: 32027255
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Adult T-cell acute lymphoblastic leukemias with il7r pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation.
    Kim R; Boissel N; Touzart A; Leguay T; Thonier F; Thomas X; Raffoux E; Huguet F; Villarese P; Fourrage C; Passini L; Hunault M; Lepretre S; Chevallier P; Braun T; Lhéritier V; Chantepie S; Maury S; Escoffre M; Tavernier E; Chalandon Y; Graux C; Macintyre E; Ifrah N; Asnafi V; Dombret H; Lhermitte L;
    Leukemia; 2020 Jul; 34(7):1730-1740. PubMed ID: 31992840
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. IL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemia.
    González-García S; Mosquera M; Fuentes P; Palumbo T; Escudero A; Pérez-Martínez A; Ramírez M; Corcoran AE; Toribio ML
    Blood; 2019 Dec; 134(24):2171-2182. PubMed ID: 31530562
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. CD4
    Niedźwiecki M; Budziło O; Adamkiewicz-Drożyńska E; Pawlik-Gwozdecka D; Zieliński M; Maciejka-Kembłowska L; Szczepański T; Trzonkowski P
    J Immunol Res; 2019; 2019():2816498. PubMed ID: 30944830
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML.
    Björklund AT; Carlsten M; Sohlberg E; Liu LL; Clancy T; Karimi M; Cooley S; Miller JS; Klimkowska M; Schaffer M; Watz E; Wikström K; Blomberg P; Wahlin BE; Palma M; Hansson L; Ljungman P; Hellström-Lindberg E; Ljunggren HG; Malmberg KJ
    Clin Cancer Res; 2018 Apr; 24(8):1834-1844. PubMed ID: 29444931
    [No Abstract]    [Full Text] [Related]  

  • 11. Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia.
    Forero-Castro M; Robledo C; Benito R; Bodega-Mayor I; Rapado I; Hernández-Sánchez M; Abáigar M; Maria Hernández-Sánchez J; Quijada-Álamo M; María Sánchez-Pina J; Sala-Valdés M; Araujo-Silva F; Kohlmann A; Luis Fuster J; Arefi M; de Las Heras N; Riesco S; Rodríguez JN; Hermosín L; Ribera J; Camos Guijosa M; Ramírez M; de Heredia Rubio CD; Barragán E; Martínez J; Ribera JM; Fernández-Ruiz E; Hernández-Rivas JM
    Br J Cancer; 2017 Jul; 117(2):256-265. PubMed ID: 28557976
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Risk stratification of adult T-cell leukemia/lymphoma using immunophenotyping.
    Kagdi HH; Demontis MA; Fields PA; Ramos JC; Bangham CR; Taylor GP
    Cancer Med; 2017 Jan; 6(1):298-309. PubMed ID: 28035765
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Increased regulatory T cells in acute lymphoblastic leukaemia patients.
    Idris SZ; Hassan N; Lee LJ; Md Noor S; Osman R; Abdul-Jalil M; Nordin AJ; Abdullah M
    Hematology; 2016 May; 21(4):206-12. PubMed ID: 26907959
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Genetic mutational profiling analysis of T cell acute lymphoblastic leukemia reveal mutant FBXW7 as a prognostic indicator for inferior survival.
    Yuan L; Lu L; Yang Y; Sun H; Chen X; Huang Y; Wang X; Zou L; Bao L
    Ann Hematol; 2015 Nov; 94(11):1817-28. PubMed ID: 26341754
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Targeted sequencing identifies associations between il7r-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia.
    Vicente C; Schwab C; Broux M; Geerdens E; Degryse S; Demeyer S; Lahortiga I; Elliott A; Chilton L; La Starza R; Mecucci C; Vandenberghe P; Goulden N; Vora A; Moorman AV; Soulier J; Harrison CJ; Clappier E; Cools J
    Haematologica; 2015 Oct; 100(10):1301-10. PubMed ID: 26206799
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Increased regulatory T cells in acute lymphoblastic leukemia patients.
    Idris SZ; Hassan N; Lee LJ; Md Noor S; Osman R; Abdul-Jalil M; Nordin AJ; Abdullah M
    Hematology; 2015 Oct; 20(9):523-9. PubMed ID: 26119924
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Clinical significance of Treg cell frequency in acute myeloid leukemia.
    Yang W; Xu Y
    Int J Hematol; 2013 Nov; 98(5):558-62. PubMed ID: 24142765
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Flow cytometric immunophenotyping of regulatory T cells in chronic lymphocytic leukemia: comparative assessment of various markers and use of novel antibody panel with cd127 as alternative to transcription factor FoxP3.
    Dasgupta A; Mahapatra M; Saxena R
    Leuk Lymphoma; 2013 Apr; 54(4):778-89. PubMed ID: 22989355
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2.
    van Bodegom D; Zhong J; Kopp N; Dutta C; Kim MS; Bird L; Weigert O; Tyner J; Pandey A; Yoda A; Weinstock DM
    Blood; 2012 Oct; 120(14):2853-63. PubMed ID: 22915648
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Elevated frequencies of CD4⁺ CD25⁺ cd127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia.
    Shenghui Z; Yixiang H; Jianbo W; Kang Y; Laixi B; Yan Z; Xi X
    Int J Cancer; 2011 Sep; 129(6):1373-81. PubMed ID: 21105040
    [TBL] [Abstract] [Full Text] [Related]  


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